44 Results for "

ACVR2

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "ACVR2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody; BYM338

Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness [2].
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2
2 Cited Publications
Cat. No.: HY-P99590
CAS No.: 1001080-50-7
Synonyms: ACE-011; MK-7962
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions [2] .
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Cat. No.: HY-P991504
LAE-102 is the selective anti-ActRIIA (activin receptor type IIA or ACVR2) monoclonal antibody. LAE-102 increases muscle mass and reduces fat mass. LAE102 can increase serum activin A levels in vivo. LAE-102 is promising for research of obesity .
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Cat. No.: HY-P99818
CAS No.: 1169766-01-1
Synonyms: ACE-031

Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy [2] .
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Cat. No.: HY-RS00246
Research Areas:  

Others

Acvr2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990327
Synonyms: humZ270 mAb

Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

The Anti-ACVR2B Antibody is a human antibody expressed in CHO cells, targeting ACVR2B. The Anti-ACVR2B Antibody has huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.42 kDa. The isotype control for the Anti-ACVR2B Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990326
Synonyms: Ab-14E1

Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

Anti-ACVR2A Antibody (Ab-14E1) is a CHO-expressed human antibody that targets ACVR2A. Anti-ACVR2A Antibody (Ab-14E1) features an IgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-ACVR2A Antibody (Ab-14E1) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS00249
Research Areas:  

Others

Acvr2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00245
Research Areas:  

Others

ACVR2A Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00247
Research Areas:  

Others

Acvr2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Acvr2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991158
CAS No.: 2996105-98-5

Target:  

TGF-β Receptor

Research Areas:  

Neurological Disease

Rinvatercept, a fusion protein, is a glycyl (1)-chimeric N-terminal (1-108)-peptide (2-109) combined from the sequences of the extracellular domains of the human ACVR2A/B, and is fused via a G3 peptide linker (110-112) to an immunoglobulin G1 (IgG1) Fc fragment. Rinvatercept can be used for research of neuromuscular disease .
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Cat. No.: HY-P703995
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-RS00248
Research Areas:  

Others

ACVR2B Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00250
Research Areas:  

Others

Acvr2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Acvr2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174782
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human ACVR2B mRNA encodes the human activin A receptor type 2B (ACVR2B) protein, a receptor that transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.
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Cat. No.: HY-P703977
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-P83050
Synonyms: ACTR2; ACTRII; ACTRIIA; ACVR2; ACVR2A

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P705726
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA (ACTR-IIA; ACTRIIA); ACVR2
Species:  
Source:  
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Cat. No.: HY-P75563
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P75537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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