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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
AH1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "AH1" in MCE Product Catalog:
49
49 Publications Verification
Synonyms: GS 4104
Target:
Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively [1].
11
11 Cited Publications
Synonyms: NP-120 tartrate; RC-61-91 tartrate
11
11 Cited Publications
Synonyms: NP-120; RC-61-91
Áreas de investigación:
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) [1]. Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
1
1 Cited Publications
Referencia número: HY-P1684
No. CAS: 1319725-20-6
Synonyms: FOXP3 inhibitor P60
Áreas de investigación:
Referencia número: HY-P4193
No. CAS: 181272-91-3
Target:
Áreas de investigación:
Referencia número: HY-13317R
No. CAS: 196618-13-0
Synonyms: GS 4104 (Standard)
Target:
Áreas de investigación:
Oseltamivir (Standard) is the analytical standard of Oseltamivir. This product is intended for research and analytical applications. Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively [1].
Target:
Áreas de investigación:
MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains [1].
Referencia número: HY-P10975
No. CAS: 2484874-12-4
Target:
Áreas de investigación:
Referencia número: HY-W713925
No. CAS: 89019-63-6
Referencia número: HY-147974
No. CAS: 1995132-67-6
Target:
Áreas de investigación:
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively [1].
Referencia número: HY-100858
No. CAS: 433238-84-7
Target:
Áreas de investigación:
PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes [1].
Referencia número: HY-175808
Target:
Áreas de investigación:
VF-57a (Compound 23) is an Influenza A virus (IAV) fusion inhibitor. VF-57 has potent antiviral activities against authentic A/H1N1 virus with EC50s of 0.92 and 0.31 μM for the A/H1N1 PR8 and A/H1N1 Virg09 strains, respectively. VF-57 significantly inhibits HA-mediated cell entry of A/H1N1- and A/H5N1-pseudoviruses, prevents the HA refolding at pH 5.2. VF-57a can be used for IAV infections research [1].
Referencia número: HY-13317S3
No. CAS: 1093851-63-8
Referencia número: HY-13317S1
Referencia número: HY-13317S4
Referencia número: HY-175796
Target:
Áreas de investigación:
Antiviral agent 70 (Compound 12b) is an antiviral agent. Antiviral agent 70 has a superior binding capacity to to NeuraminidaseA/H1N1 virus with an IC50 of 2.9 μM. Antiviral agent 70 can be used for influenza virus infections research [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
