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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
494 Results for "
Acetylcholinesterase
" in MedChemExpress (MCE) Product Catalog:
Products (494)
494 Results for "Acetylcholinesterase" in MCE Product Catalog:
Cat. No.: HY-P2860B
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Acetylcholinesterase (EC 3.1.1.7) acts on a variety of acetic esters; also catalyses transacetylations.
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161 Publications Verification
Synonyms: Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
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PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible serine proteases inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .
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13 Cited Publications
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α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
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10 Cited Publications
Cat. No.: HY-W112938
CAS No.: 92739-63-4
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TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand. TMPyP4 tosylate inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate is a telomerase inhibitor and inhibits cancer cells proliferation. TMPyP4 tosylate is also a stabilizer of nucleic acid secondary structure and an acetylcholinesterase inhibitor. Besides, TMPyP4 tosylate has antiviral activity against SARS-CoV-2 .
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Neurological Disease Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Cancer
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Environmental Pollutants Apoptosis Cholinesterase (ChE) Insecticide Reactive Oxygen Species (ROS)
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Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .
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6 Cited Publications
Cat. No.: HY-N0826
CAS No.: 18797-79-0
Corynoline is an orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline exhibits multiple activities including anti-inflammatory, antinociceptive, antitumor and analgesic effects. Corynoline can be used in the research of diseases such as tumors and inflammatory pain .
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Alkaloids Neurological Disease Anti-aging Huperziaceae Terpenoids Sesquiterpenes Pyridine Alkaloids Huperzia serrata (Thunb. ex Murray) Trevis. Plants Disease Research Fields
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4 Cited Publications
Synonyms: Gelseminic acid; Chrysatropic acid
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Coumarins Plants Monophenols Leguminosae Rubiaceae Phenols Phenylpropanoids Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology Hedyotis diffusa Willd.
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4 Cited Publications
Cat. No.: HY-P2161B
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Alkaloids Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Disease Research Fields Inflammation/Immunology
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Apocynaceae Flavonols Flavonoids Other Diseases Phenols Polyphenols Plants Apocynum venetum Linn. Disease Research Fields
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3 Cited Publications
Cat. No.: HY-17541A
CAS No.: 2197053-49-7
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Cysteine Protease inhibitor hydrochloride, an inhibitor of Cysteine Protease, binds to acetylcholinesterase (AChE). Cysteine Protease inhibitor hydrochloride is applicable to the research of Alzheimer's disease .
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Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
