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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Adenine derivatives
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Adenine derivatives" in MCE Product Catalog:
25
25 Cited Publications
Cat. No.: HY-W015213
CAS No.: 6055-72-7
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7 Cited Publications
Synonyms: 6-FurfurylAdenine; N6-FurfurylAdenine
Category:
Natural Products other families Neurological Disease Plants Phytohormone Disease Research Fields Cytokinin Agricultural Research
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Cat. No.: HY-W018326
CAS No.: 113942-30-6
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Temozolomide acid is a carboxylic acid derivative of Temozolomide (HY-17364) with anticancer activity. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid is promising for research of glioblastoma and brain cancer .
Cat. No.: HY-W008129
CAS No.: 2584-71-6
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Amino acids Disease Research Fields
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Cat. No.: HY-W250153
CAS No.: 109434-21-1
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Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
Cat. No.: HY-W007367
CAS No.: 5451-40-1
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2,6-Dichloropurine is a purine derivative, PDE inhibitor analog, and synthetic intermediate for N 7-glycosylated purine nucleosides, nucleosides and nucleotides. 2,6-Dichloropurine is applicable to cancer-related research .
Synonyms: 6-FurfurylAdenine (Standard); N6-FurfurylAdenine (Standard)
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Cat. No.: HY-148172
CAS No.: 210474-65-0
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L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC50=1.5 μM) and anti-hepatitis B virus (HBV) (EC50=1.7 μM) activity. L-Fd4A has low cytotoxicity .
Cat. No.: HY-161712
CAS No.: 2427862-70-0
IMPDH-IN-4 is a derivative of N-pyridinylthiophene carboxamid that exhibits activity against peripheral nerve sheath carcinoma cells. IMPDH-IN-4 is metabolized by NAMPT and NMNAT1 to an adenine dinucleotide (AD) derivative, which is an NAD analog and can inhibit inosine monophosphate dehydrogenase (IMPDH), leading to the accumulation of inosine monophosphate (IMP) in cells. IMPDH-IN-4 has good blood-brain barrier permeability and can be used in the study of central and peripheral nervous system cancers .
Synonyms: Mutagenic impurity of tenofovir disoproxil
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9-Propenyladenine (Mutagenic impurity of tenofovir disoproxil) is a purine derivative mutagenic impurity of Tenofovir Disoproxil (HY-13782A), and also serves as a capping group intermediate in the synthesis of N-substituted purines .
Cat. No.: HY-W076740
CAS No.: 6974-78-3
Synonyms: 8-Bromo-9H-purin-6-amine
Cat. No.: HY-N9422
CAS No.: 936827-87-1
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Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
Cat. No.: HY-177787A
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2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
Cat. No.: HY-W250153A
Cat. No.: HY-134280
CAS No.: 477782-33-5
Synonyms: Nicotinamide 8-Br-hypoxanthine dinucleotide
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8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .
Cat. No.: HY-W015213S
Cat. No.: HY-159916
CAS No.: 3031612-90-2
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AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity .
Cat. No.: HY-100079R
CAS No.: 1446486-33-4
Synonyms: Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)
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9-Propenyladenine (Standard) (Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)) is the analytical standard of 9-Propenyladenine (HY-100079). This product is intended for research and analytical applications. 9-Propenyladenine (Mutagenic impurity of tenofovir disoproxil) is a purine derivative mutagenic impurity of Tenofovir Disoproxil (HY-13782A), and also serves as a capping group intermediate in the synthesis of N-substituted purines .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
