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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Aggression
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Aggression" in MCE Product Catalog:
8
8 Publications Verification
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L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .
2
2 Cited Publications
Synonyms: Imidazolyl-4-acetic acid
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Synonyms: Dehydroepiandrosterone 3-acetate; DHEA acetate
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Target:
1
1 Cited Publications
Cat. No.: HY-N2411
CAS No.: 60314-89-8
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Cat. No.: HY-W004305
CAS No.: 629-80-1
Synonyms: Palmitaldehyde
Cat. No.: HY-178323
CAS No.: 3048608-87-0
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MW073 is a highly selective and orally active 5-HT2BR antagonist (IC50 =70 nM). MW073 exerts its effects by concentration-dependently inhibiting receptor activity and β-arrestin-1 recruitment. MW073 ameliorates synaptic plasticity and behavioral deficits, including aggression, in Alzheimer’s disease (AD) mouse models. MW073 can be used for Alzheimer’s disease (AD) research [1][2].
Cat. No.: HY-133171A
CAS No.: 126924-38-7
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(S)-Norfluoxetine, a S enantiomer of Norfluoxetine (HY-135556), is a selective serotonin reuptake inhibitor. (S)-Norfluoxetine can increase allopregnanolone levels and reduce aggression in socially isolated mice .
Cat. No.: HY-W004305R
CAS No.: 629-80-1
Synonyms: Palmitaldehyde (Standard)
Synonyms: Dehydroepiandrosterone 3-acetate (Standard); DHEA acetate (Standard)
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Research Areas:
Dehydroisoandrosterone 3-acetate (Standard) is the analytical standard of Dehydroisoandrosterone 3-acetate. This product is intended for research and analytical applications. Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression.
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Cat. No.: HY-103403
CAS No.: 156907-84-5
Synonyms: PNU96391 hydrochloride
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(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability .
Cat. No.: HY-W673589
CAS No.: 1561-02-0
Synonyms: 2-Me-C26
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2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone. It has been found in the cuticle of M. dasystomus females, but not males, where it contributes to the mating behavior of males, as well as in D. melanogaster females where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.
Cat. No.: HY-113413R
CAS No.: 645-65-8
Synonyms: Imidazolyl-4-acetic acid (Standard)
Cat. No.: HY-W004305S
CAS No.: 2703602-66-6
Synonyms: Palmitaldehyde-d5
Cat. No.: HY-108677R
CAS No.: 160312-62-9
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L-368,899 hydrochloride (Standard) is the analytical standard of L-368,899 hydrochloride (HY-108677). This product is intended for research and analytical applications. L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .
Cat. No.: HY-L121
423 compounds
5-HT receptors, also called Serotonin receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. These receptors are now classified into seven families, 5-HT1–7, comprising a total of 14 structurally and pharmacologically distinct mammalian 5-HT receptor subtypes. The 5-HT receptors influence various biological and neurological processes such as aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, andthermoregulation. The serotonin receptors are the target of a variety of pharmaceutical drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens.
MCE 5-HT Receptor Compound Library consists of 423 5-HT receptor inhibitors and activators, which can be used for neuropsychiatric disorders drugs discovery.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
