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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
49 Results for "
Antitumor bioactivity
" in MedChemExpress (MCE) Product Catalog:
Products (49)
49 Results for "Antitumor bioactivity" in MCE Product Catalog:
22
Category:
Neurological Disease Metabolic Disease Plants Endogenous metabolite Human Gut Microbiota Metabolites Iridoids Terpenoids Rubiaceae Gardenia jasminoides Ellis Disease Research Fields Inflammation/Immunology
Target:
10
10 Cited Publications
Cat. No.: HY-N0234
CAS No.: 19879-30-2
Synonyms: 7-O-Methylbavachin; Bavachinin A
Category:
Flavonoids Monophenols Leguminosae Flavonones Phenols Psoralea corylifolia L. Plants Disease Research Fields Inflammation/Immunology
Target:
7
Category:
Neurological Disease Rhododendron dauricum Linn. Plants Flavonoids Flavonones Phenols Polyphenols Ericaceae Disease Research Fields Inflammation/Immunology
Target:
6
Target:
Research Areas:
Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis .
5
5 Cited Publications
Cat. No.: HY-N0047
CAS No.: 50773-41-6
5
Category:
Infection Flavonoids Flavones Plants Compositae Disease Research Fields Genista maderensis (Webb & Berthel.) Lowe Inflammation/Immunology
Target:
2
2
2 Cited Publications
Target:
Research Areas:
14-3-3η Protein inhibitor 1 (Compound C11) is a 14-3-3η protein inhibitor with a KD of 35 µM. 14-3-3η Protein inhibitor 1 shows inhibitory activities against several typical human liver cancer cell lines. 14-3-3η Protein inhibitor 1 induces cell apoptosis and G1-S cell cycle arrest with good metabolic stability .
Cat. No.: HY-N6246
CAS No.: 25368-11-0
Cat. No.: HY-N1517
CAS No.: 103773-62-2
Category:
Triterpenes Microorganisms Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields Cancer
Target:
Target:
Research Areas:
DNMT/HDAC-IN-1 (Compund 15a) is a dual DNMT and HDAC inhibitor with IC50 values for HDAC1 and HDAC6 are 56.84 nM and 17.39 nM respectively. DNMT/HDAC-IN-1 can induce apoptosis and be used in tumor research.
Cat. No.: HY-P3732
CAS No.: 332179-76-7
Cat. No.: HY-P5322
CAS No.: 138849-26-0
Target:
Research Areas:
Category:
Cardiovascular Disease Metabolic Disease Plants Moraceae Flavonoids Phenols Polyphenols Maclura pomifera (Raf.) Schneid. Disease Research Fields Inflammation/Immunology Isoflavones
Target:
Cat. No.: HY-N0446
CAS No.: 19685-10-0
Category:
Alkaloids Quinoline Alkaloids Camptotheca acuminata Decne. Plants Nyssaceae Disease Research Fields Cancer
Target:
Cat. No.: HY-158346
CAS No.: 2922287-81-6
Target:
Research Areas:
RP-2119 is an orally bioactive Polymerase Theta (Polθ) inhibitor, with an IC50 of 0.7 nM against human Polθ ATPase. RP-2119 reduces Polθ activity and exerts antiproliferative effects in BRCA2-deficient cancer cells. RP-2119 exhibits antitumor activity in BRCA2-deficient cancer cell xenograft mouse models . RP-2119 can be used for the research of cancer and homologous recombination-deficient cancers, including brca1/brca2-mutant cancers and shld2-mutant cancers .
Cat. No.: HY-N7591
CAS No.: 1393922-01-4
Category:
Flavonoids Chalcones Leguminosae Millettia pachycarpa Benth. Plants Disease Research Fields Cancer
Target:
Cat. No.: HY-128871
CAS No.: 2130869-17-7
Target:
Research Areas:
VCP-Eribulin is a bioactive molecule-linker conjugate designed for ADCs (Drug-Linker Conjugates for ADC), formed by conjugating an ADC linker (VCP) with Eribulin (HY-13442). Eribulin is a unique microtubule inhibitor exhibiting antitumor activity. VCP-Eribulin can be utilized for antibody conjugation .
Category:
Human Gut Microbiota Metabolites Iridoids Terpenoids Rubiaceae Plants Gardenia jasminoides Ellis Endogenous metabolite
Target:
Cat. No.: HY-153067
CAS No.: 2578019-72-2
Research Areas:
Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan (Compound 11) is a bioactive compound-linker conjugate for ADC. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can conjugate with antibodies to form ADC (C-11) with anti-tumor activity. Exatecan is a DNA Topoisomerase I inhibitor. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can be used in the research of squamous cell carcinoma, pancreatic adenocarcinoma and colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
