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Arachidonic acid methyl ester

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apolipoprotein (1) Biochemical Assay Reagents (3) Drug Metabolite (1) Isotope-Labeled Compounds (4) PKC (1) Prostaglandin Receptor (1)
By Research Areas:	Inflammation/Immunology (3) Metabolic Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Isotope-Labeled Compounds

Targets Recommended: CETP Carboxylesterase (CES) Hormone-Sensitive Lipase (HSL)

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-W011297S1

Methyl arachidonate-d8 Arachidonic acid methyl ester-d₈	Isotope-Labeled Compounds	Others
Methyl arachidonate-d₈ is the deuterium labeled Arachidonic acid methyl ester .

HY-W011297

Methyl arachidonate Arachidonic acid methyl ester	PKC	Metabolic Disease
Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy .

HY-165061

5(Z),11(Z),14(Z)-Eicosatrienoic acid Sciadonic acid	Apolipoprotein	Inflammation/Immunology
5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid), a polyunsaturated fatty acid sourced from maritime pine seed oil, gymnospermae leaves and seeds, and freshwater gastropods, has been shown to reduce high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1 when included in their diet. In vitro studies indicate that it diminishes cholesterol efflux, and when applied topically in its methyl ester form, it alleviates inflammatory processes, likely by displacing arachidonic acid from phospholipid pools and lowering concentrations of downstream inflammatory mediators such as prostaglandin E2 and leukotrienes.

HY-120978

*Omega-3 arachidonic* acid methyl ester** ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester	Biochemical Assay Reagents	Others
omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

HY-112621

Leukotriene A4 methyl ester LTA4 methyl ester	Biochemical Assay Reagents	Inflammation/Immunology
Leukotriene A4 methyl ester (LTA4 methyl ester) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

HY-W011297S2

Methyl arachidonate-13C4 Arachidonic acid methyl ester-13C₄	Isotope-Labeled Compounds Others	Metabolic Disease
Methyl arachidonate- ¹³C₄ (Arachidonic acid methyl ester- ¹³C₄) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a *fatty acid methyl* ester** resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-W011297S

Methyl arachidonate-d5 Arachidonic acid methyl ester-d₅	Isotope-Labeled Compounds	Others
Methyl arachidonate-d₅ is the deuterium labeled Arachidonic acid methyl ester .

HY-126722

Lipoxin A4 methyl ester	Biochemical Assay Reagents	Inflammation/Immunology
Lipoxin A4 methyl ester is a stable synthetic analog of lipoxin with anti-inflammatory properties that can be extracted from arachidonic acid .

HY-W011297S3

Methyl arachidonate-13C5 Arachidonic acid methyl ester-¹³C₅	Isotope-Labeled Compounds Others	Metabolic Disease
Methyl arachidonate- ¹³C₅ (Arachidonic acid methyl ester- ¹³C₅) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a *fatty acid methyl* ester** resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-176074

U-46619 Glycine methyl ester	Prostaglandin Receptor	Others
U-46619 Glycine methyl ester has a modification at the C-1 position of U-46619, which uniquely alter its binding properties to the TP receptor or any of the PGH₂-metabolizing enzymes. U-46619 is a stable analog of the endoperoxide PGH₂. U-46619 is also an agonist of TP receptor. U-46619 can change the shape of platelet, aggregation and contraction of vascular smooth muscle. U-46619 Glycine methyl ester can be studied in research to explore the inhibition of various enzymes in the arachidonic acid metabolic pathway. U-46619 Glycine methyl ester can also act as a lipophilic prodrug form of U-46619 that alters its distribution and pharmacokinetic properties .

HY-165005

14S(15R)-EET methyl ester	Drug Metabolite	Metabolic Disease
14S(15R)-EET methyl ester is an oxylipin and a cytochrome P450 metabolite of Arachidonic acid (HY-109590).

Cat. No.	Nombre del producto	Type

HY-120978

*Omega-3 arachidonic* acid methyl ester** ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester	Biochemical Assay Reagents
omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

Omega-3 arachidonic acid methyl ester

ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester

Biochemical Assay Reagents

omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.

Cat. No.	Nombre del producto	Chemical Structure

HY-W011297S1

Methyl arachidonate-d8
Methyl arachidonate-d₈ is the deuterium labeled Arachidonic acid methyl ester .

HY-W011297S2

Methyl arachidonate-13C4
Methyl arachidonate- ¹³C₄ (Arachidonic acid methyl ester- ¹³C₄) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a *fatty acid methyl* ester** resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-W011297S

Methyl arachidonate-d5
Methyl arachidonate-d₅ is the deuterium labeled Arachidonic acid methyl ester .

HY-W011297S3

Methyl arachidonate-13C5
Methyl arachidonate- ¹³C₅ (Arachidonic acid methyl ester- ¹³C₅) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a *fatty acid methyl* ester** resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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