79 Results for "

Azetidine

" in MedChemExpress (MCE) Product Catalog:
Products (79)

79 Results for "Azetidine" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-W050044
CAS. Nr.: 2133-34-8
L-Azetidine-2-carboxylic acid is a proline analog. L-Azetidine-2-carboxylic acid upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway. L-Azetidine-2-carboxylic acid increases pro-apoptotic BAX protein. L-Azetidine-2-carboxylic acid induces ATF6 cleavage and upregulates phosphorylated eIF2α levels. L-Azetidine-2-carboxylic acid induces ER stress, inducing protein misfolding and aggregation. L-Azetidine-2-carboxylic acid shows teratogenic, pro-inflammatory and pro-apoptotic effects .
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1
1 Cited Publications
Art. -Nr.: HY-75308
CAS. Nr.: 2517-04-6
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent .
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Art. -Nr.: HY-Y0530
CAS. Nr.: 36476-78-5
Forschungsgebiete:  

Cancer

Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
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Art. -Nr.: HY-40141
CAS. Nr.: 142253-55-2
Forschungsgebiete:  

Cancer

1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
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Art. -Nr.: HY-33615
CAS. Nr.: 100202-39-9
Forschungsgebiete:  

Cancer

Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
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Art. -Nr.: HY-40151
CAS. Nr.: 610791-05-4
Forschungsgebiete:  

Cancer

Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1
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Art. -Nr.: HY-40145
CAS. Nr.: 254454-54-1
1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence .
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Art. -Nr.: HY-40152
CAS. Nr.: 142253-56-3
Forschungsgebiete:  

Cancer

1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Art. -Nr.: HY-W021909
CAS. Nr.: 253176-93-1
Target:  

PROTAC Linkers

Forschungsgebiete:  

Cancer

tert-Butyl 3-(bromomethyl)azetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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Art. -Nr.: HY-131349
CAS. Nr.: 2174938-70-4
Reinheit:  98.95%
Target:  

CCR

Forschungsgebiete:  

Cancer

CCR4-351 is an orally active, potent and selective CCR4 antagonist. CCR4-351, featuring a novel piperidinyl-azetidine motif, has IC50s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 has antitumor activity .
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Art. -Nr.: HY-W010628
CAS. Nr.: 36520-39-5
Synonyms: Trimethyleneimine hydrochloride
Azetidine (Trimethyleneimine) hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Azetidine hydrochloride is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .
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Art. -Nr.: HY-W017755
CAS. Nr.: 7729-30-8
Forschungsgebiete:  

Cancer

(R)-Azetidine-2-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-Azetidine-2-carboxylic acid is also a alkyl chain-based PROTAC linker that can be
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Art. -Nr.: HY-40347
CAS. Nr.: 898271-20-0
Target:  

PROTAC Linkers

Forschungsgebiete:  

Cancer

Boc-Azetidine-C2-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
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Art. -Nr.: HY-W018751
CAS. Nr.: 228857-58-7
Target:  

Drug Intermediate

Forschungsgebiete:  

Others

1-Boc-D-azetidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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Art. -Nr.: HY-W011277
CAS. Nr.: 193693-64-0
Forschungsgebiete:  

Cancer

Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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Art. -Nr.: HY-401504
CAS. Nr.: 2412058-13-8
Forschungsgebiete:  

Cancer

Thalidomide-azetidine-COOH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Art. -Nr.: HY-W998240
CAS. Nr.: 2241314-93-0
Forschungsgebiete:  

Cancer

Thalidomide-azetidine-C-OH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Art. -Nr.: HY-144870
CAS. Nr.: 2237955-91-6
Target:  

STAT

Forschungsgebiete:  

Cancer

STAT3-IN-7, an aryl sulfonamido azetidine compound, is an orally active STAT3 inhibitor. STAT3-IN-7 has anticancer activities (WO2021016333A1, H182) .
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Art. -Nr.: HY-W052600
CAS. Nr.: 405090-31-5
Forschungsgebiete:  

Cancer

Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
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Art. -Nr.: HY-W004868
CAS. Nr.: 97628-92-7
Forschungsgebiete:  

Cancer

1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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