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Isoforms Recommended: CCR3
Results for "

CCR3

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

1

Inhibitory Antibodies

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-U00331
    CCR3 antagonist 1
    1 Publications Verification

    		 CCR Inflammation/Immunology Endocrinology
    CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases.
    <em>CCR3</em> antagonist 1
  • HY-103360
    J-113863
    3 Publications Verification

    		 CCR Inflammation/Immunology
    J-113863 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect [3].
    J-113863
  • HY-RS02154
    CCR3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CCR3 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CCR3 Human Pre-designed siRNA Set A
    CCR3 Human Pre-designed siRNA Set A
  • HY-RS02155
    Ccr3 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ccr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccr3 Mouse Pre-designed siRNA Set A
    Ccr3 Mouse Pre-designed siRNA Set A
  • HY-RS02156
    Ccr3 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ccr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccr3 Rat Pre-designed siRNA Set A
    Ccr3 Rat Pre-designed siRNA Set A
  • HY-N10397
    Maceneolignan H

    		CCR Inflammation/Immunology
    Maceneolignan H (Compound 8) is a neolignane compound isolated from the arils of Myristica fragrans. Maceneolignan H is a selective CCR3 antagonist (EC50 = 1.4 μM). Maceneolignan H has the potential for the research of allergic diseases .
    Maceneolignan H
  • HY-136788
    ALK4290

    AKST4290

    		 CCR Neurological Disease Inflammation/Immunology
    ALK4290 (AKST4290) is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3 . ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism [3].
    ALK4290
  • HY-103360B
    trans-J-113863

    		CCR Inflammation/Immunology
    trans-J-113863 is a potent chemokine CCR1 and CCR3 receptor antagonist, and inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC50 of 9.57 and 93.8 nM,respectively .
    trans-J-113863
  • HY-103363
    SB-328437
    1 Publications Verification

    		 CCR Inflammation/Immunology
    SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM .
    SB-328437
  • HY-103361
    SB297006
    1 Publications Verification

    		 CCR Neurological Disease Endocrinology
    SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.
    SB297006
  • HY-160998
    YM-344031

    		CCR Inflammation/Immunology
    YM-344031 is an orally active antagonist for CCR3. YM-344031 inhibits binding of Eotaxin-1 and RANTES to CCR3, with IC50 of 3.0 and 16.3 nM. YM-344031 inhibits ligand-induced rise in intracellular Ca [2+] and the ligand-induced chemotaxis. YM-344031 inhibits eotaxin-1-induced changes in eosinophil morphology in macaques blood, and prevents allergic skin reactions in a mouse allergy model .
    YM-344031
  • HY-107051
    GW 766994
    2 Publications Verification

    GW 994

    		 CCR Inflammation/Immunology Endocrinology
    GW 766994 (GW 994) is an orally active and specific chemokine receptor-3 (CCR3) antagonist. GW 766994 has the potential for asthma and eosinophilic bronchitis research .
    GW 766994
  • HY-136788A
    ALK4290 dihydrochloride

    AKST4290 dihydrochloride

    		 CCR Inflammation/Immunology
    ALK4290 dihydrochloride (AKST4290 dihydrochlorid) is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3 . ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism [3].
    ALK4290 dihydrochloride
  • HY-P3982
    CKLF1-C19

    		CCR Inflammation/Immunology
    CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). CKLF1-C19 interacts with CCR4, and inhibits chemotaxis induced by both CKLF1 and CCL17. CKLF1-C19 can suppress allergic lung inflammation via inhibiting chemotaxis mediated by CCR3 and CCR4 .
    CKLF1-C19
  • HY-19974
    TAK-220
    2 Publications Verification

    		 CCR HIV Infection Endocrinology
    TAK-220 is a selective and orally bioavailable CCR5 antagonist, with IC50s of 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively, but shows no effect on the binding to CCR1, CCR2b, CCR3, CCR4, or CCR7; TAK-220 also selectively inhibits HIV-1, with EC50s of 1.2 nM (HIV-1 KK), 0.72 nM (HIV-1 CTV), 1.7 nM (HIV-1 HKW), 1.7 nM (HIV-1 HNK), 0.93 nM (HIV-1 HTN), and 0.55 nM (HIV-1 HHA), and EC90s of 12 nM (HIV-1 KK), 5 nM (HIV-1 CTV), 12 nM (HIV-1 HKW), 28 nM (HIV-1 HNK), 15 nM (HIV-1 HTN), and 4 nM (HIV-1 HHA) in PBMCs.
    TAK-220
  • HY-120629
    BMS-639623

    		CCR Inflammation/Immunology
    BMS-639623 is a potent and orally activeCCR3 antagonist with an IC50 of 0.3 nM. BMS-639623 picomolar inhibition potency against eosinophil chemotaxis (IC50=38 pM). BMS-639623 can be used for the research of asthma .
    BMS-639623

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