62 Results for "

CEA

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "CEA" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99011
CAS No.: 1855925-27-7
Synonyms: RG-7802; RO-6958688; CEA-TCB

Target:  

CD3

Research Areas:  

Cancer

Cibisatamab, a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab can be used for colorectal cancer research .
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2
2 Cited Publications
Cat. No.: HY-P70675
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM5; Cell Adhesion Molecule CEACAM5; Prev. CEA; Meconium Antigen 100; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Isoform 5D; CD66e; Carcinoembryonic Antigen-Related Cell Adhesio
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-14423
CAS No.: 342577-38-2
Purity:  99.21%
Synonyms: S2367
Velneperit (S-2367) is an orally active neuropeptide Y (NPY) Y5 receptor antagonist that can penetrate the blood-brain barrier. Velneperit inhibits the appetite-stimulating and metabolism-inhibiting effects mediated by NPY. Velneperit selectively improves diet-induced obesity in mice. Velneperit enhances the expression of fear acutely by removing the inhibition of CeA Drd2 neurons. Velneperit can be used for the study of obesity .
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1
1 Cited Publications
Cat. No.: HY-P78397
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CEACAM6; Cell Adhesion Molecule CEACAM6; Prev. NCA; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6; NCA-50/90; Non-Specific Crossreacting Antigen; CD66c; Cluster Of Differentiation 66c; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99160
CAS No.: 219649-07-7
Synonyms: hMN14

Research Areas:  

Cancer

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy .
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Cat. No.: HY-P99498
CAS No.: 1509916-03-3
Synonyms: CEA-IL2v; RG 7813; RO 6895882

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities .
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Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Carcinoembryonic antigen peptide 1 (CEA peptide) is a 9-amino acid HLA-A0201-binding cytotoxic T lymphocyte (CTL) epitope peptide derived from carcinoembryonic antigen (CEA). The IC50 of Carcinoembryonic antigen peptide 1 binding to HLA-A0201 is 2 μM. Carcinoembryonic antigen peptide 1 binds to HLA-A0201 to form a peptide-MHC I complex, which is recognized by the T cell receptor (TCR) of CAP1-specific CD8 + CTLs, thereby inducing antigen-specific T cell activation, IFN-γ production, and CTL-mediated lysis of target cells. Carcinoembryonic antigen peptide 1 is used in research on CEA-specific CTL responses and colorectal cancer .
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Cat. No.: HY-P991060
CAS No.: 1622305-37-6

Research Areas:  

Cancer

Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498) .
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Cat. No.: HY-P991068

Research Areas:  

Cancer

hT84.66-M5A is a humanized IgG1 antibody that targets carcinoembryonic antigen (CEA). The isotype control for hT84.66-M5A can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-178238
CAS No.: 3040077-52-6
Research Areas:  

Cancer

LD2-3 is a cytotoxic compound derived from Exatecan (HY-13631), designed to be conjugated with anti-FGFR2b or anti-CEA antibodies to form intact antibody-drug conjugate (ADC) molecules. LD2-3 exhibits a remarkable bystander killing effect: it not only effectively kills FGFR2b-positive tumor cells, but also eliminates surrounding FGFR2b-negative cells in co-culture and mixed tumor xenograft models, thereby inducing complete tumor regression. LD2-3 can be used for anti-tumor research in relevant fields such as gastric cancer and lung cancer .
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Cat. No.: HY-P99691
CAS No.: 250242-54-7
Synonyms: IMMU-MN3
Lemalesomab (IMMU-MN3) is a Fab' fragment of a murine anti-granulocyte monoclonal antibody targeting NCA-90 (CEACAM6). Lemalesomab binds strongly to NCA-90 on the surface of granulocytes, cross-reacts with epitopes of other CEA family members, and blocks the binding between human colon adenocarcinoma cells and CEA. When labeled with 99mTc, Lemalesomab can be used for radionuclide imaging of soft tissue infections and osteomyelitis .
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Cat. No.: HY-P991469
Synonyms: MEDI-565

Research Areas:  

Cancer

AMG-211 (MEDI-565)i s a bispecific antibody targeting CD3E and CEACAM5/CEA/CD66e. AMG-211 can be used in Gastrointestinal cancer and Solid tumours research .
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Cat. No.: HY-P991563

Target:  

Inhibitory Antibodies

Research Areas:  

Others

Anti-CEACAM5 Antibody (A5B7) is a humanized antibody expressed in CHO cells, targeting CEACAM5/CEA/CD66e. Anti-CEACAM5 Antibody (A5B7) consists of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for the Anti-CEACAM5 Antibody (A5B7) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-155446
Target:  

Hapten

Research Areas:  

Inflammation/Immunology Cancer

di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients .
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Cat. No.: HY-RS02441
Research Areas:  

Others

CEACAM5 Human Pre-designed siRNA Set A contains three designed siRNAs for CEACAM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P9937
CAS No.: 154361-48-5
Synonyms: IMMU-4

Research Areas:  

Cancer

Arcitumomab is a murine anti-carcinoembryonic antigen (CEA) monoclonal antibody Fab’ fragment. Arcitumomab can be labeled with technetium-99m and can be used for single-photon emission computed tomography (SPECT) imaging .
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Cat. No.: HY-117361
CAS No.: 103828-81-5
Research Areas:  

Cancer

LY207702 is a difluorinated purine nucleoside with antitumor activity and cardiotoxicity. LY207702 is cytotoxic to CEA-positive LS174T cells (IC50=0.302 μg/mL). LY207702 can be used in the study of colon cancer .
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Cat. No.: HY-RS03333
Research Areas:  

Others

Ctse Rat Pre-designed siRNA Set A contains three designed siRNAs for Ctse gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11281
Research Areas:  

Others

PSG2 Human Pre-designed siRNA Set A contains three designed siRNAs for PSG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS02439
Research Areas:  

Others

CEACAM3 Human Pre-designed siRNA Set A contains three designed siRNAs for CEACAM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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