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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
CHA
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "CHA" in MCE Product Catalog:
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13 Publications Verification
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α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 µM) and acetylcholinesterase (AChE; IC50=300 µM). α-NETA has anti-cancer activity .
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DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes .
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N6-Cyclohexyladenosine is a selective adenosine A1 receptor agonist (EC50 = 8.2 nM). N6-Cyclohexyladenosine enhances the activation of the PI3K/Akt/CREB/BDNF axis. N6-Cyclohexyladenosine promotes remyelination, induces sleep, and improves 3-NP-induced Huntington's disease. N6-Cyclohexyladenosine can be used in liver cancer research .
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1 Cited Publications
Cat. No.: HY-108368A
CAS No.: 2098500-94-6
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Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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1 Cited Publications
Cat. No.: HY-P70909
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Microtubule-associated proteins 1A/1B light CHAin 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light CHAin 3-like protein 2; MAP1A/MAP1B light CHAin 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light CHA
Cat. No.: HY-P5506
CAS No.: 144555-23-7
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CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa .
Cat. No.: HY-W011000
CAS No.: 135673-97-1
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Cat. No.: HY-P1390
CAS No.: 500170-27-4
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Synonyms: L-azidovaline CHA
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N3-L-Val-OH (L-azidovaline) (CHA) is a mixture of N3-L-Val-OH and Cyclohexanamine. N3-L-Val-OH is a non-natural amino acid building block specifically designed for solid-phase peptide synthesis and click chemistry. N3-L-Orn(Fmoc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM) .
Cat. No.: HY-P5372A
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Cat. No.: HY-P10043
CAS No.: 150956-93-7
Cat. No.: HY-P6027A
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Cat. No.: HY-P4040
CAS No.: 208940-40-3
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Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Cat. No.: HY-151674
CAS No.: 1286670-90-3
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N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-P1390A
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Cat. No.: HY-P3098
CAS No.: 256394-94-2
Cat. No.: HY-151763
CAS No.: 2098496-88-7
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Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-151722
CAS No.: 1858224-18-6
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Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
