Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
COMP
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "COMP" in MCE Product Catalog:
2
1
1 Cited Publications
Target:
Forschungsgebiete:
N3-PEG3-VC-PAB-MMAF (Comp T-88-5) is a drug-linker conjugate containing the ADC linker N3-PEG3-VC-PAB and the tubulin inhibitor MMAF . N3-PEG3-VC-PAB-MMAF is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
1
1 Cited Publications
Art. -Nr.: HY-N12492
CAS. Nr.: 25460-12-2
Target:
Art. -Nr.: HY-164788
CAS. Nr.: 3049886-19-0
Forschungsgebiete:
GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC. GGFG-PAB-MMAE contains the ADC linker (GGFG-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162) .
Art. -Nr.: HY-165607S
CAS. Nr.: 3058199-58-6
Target:
Forschungsgebiete:
ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research .
Art. -Nr.: HY-P10723
CAS. Nr.: 2894052-23-2
Target:
Forschungsgebiete:
HSP90-IN-23 (Comp 12-1) is an inhibitor of heat shock protein 90(HSP90) with an IC50 of 9 nM. HSP90-IN-23 induces apoptosis of tumor cells and arrests the tumor cell cycle in G0/G1 phase. HSP90-IN-23 can be used for cancer research .
Kras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566) .
FLT3-IN-19 (Comp 50) is a potent and selective FLT3 inhibitor with IC50 of 0.213 nM. FLT3-IN-19 can be used in AML disease research .
Art. -Nr.: HY-145775
CAS. Nr.: 1425051-22-4
Target:
Forschungsgebiete:
hIgG–hFc receptor-IN-1 (comp 66) is a human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein-protein interaction inhibitor, with an IC50 of 2 μM .
Art. -Nr.: HY-153930
CAS. Nr.: 478040-08-3
Target:
Forschungsgebiete:
h15-LOX-2 inhibitor 1 (Comp 105) is a human epithelial 15-lipoxygenase-2 (h15-LOX-2) inhibitor with IC50 of 0.34 μM .
Target:
Forschungsgebiete:
(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ .
Art. -Nr.: HY-RS03015
Target:
Forschungsgebiete:
COMP Human Pre-designed siRNA Set A contains three designed siRNAs for COMP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-156670
CAS. Nr.: 2873460-51-4
Target:
Forschungsgebiete:
Camptothecin analog-1 (Comp 166) is a camptothecin analog .
Art. -Nr.: HY-156875
CAS. Nr.: 2472030-28-5
Target:
Forschungsgebiete:
20-HETE inhibitor-1 (comp 83) is a 20-HETE formation inhibitor
Art. -Nr.: HY-164560
CAS. Nr.: 3047242-55-4
MALT1-IN-14 (comp 2) is a MALT1 inhibitor, with an IC50 of 0.081 μM .
Art. -Nr.: HY-145865
CAS. Nr.: 2581082-16-6
Antiproliferative against-3 (comp 33) shows a prominent activity against Hela (IC50 = 0.21 µM), A549 (IC50 = 0.39 µM), and MCF-7 (IC50 = 0.33 µM), respectively. Antiproliferative against-3 (comp 33) also dose dependently induces apoptosis by arresting A549 cells at G1 phase .
Target:
Forschungsgebiete:
p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
