136 Results for "

Cholesteryl

" in MedChemExpress (MCE) Product Catalog:
Products (136)

136 Results for "Cholesteryl" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-D1168
CAS No.: 1320-06-5
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .
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2 Cited Publications
Cat. No.: HY-14950
CAS No.: 211513-37-0
Purity:  99.19%
Synonyms: JTT-705; RO4607381
Target:  

CETP

Research Areas:  

Cardiovascular Disease Cancer

Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
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1 Cited Publications
Cat. No.: HY-113217
CAS No.: 303-43-5
Purity:  ≥99.0%
Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
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1 Cited Publications
Cat. No.: HY-N2339
CAS No.: 61510-09-6
Synonyms: Cholesteryl docosanoate; Cholesterol behenate
Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.
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Cat. No.: HY-W010800
CAS No.: 1510-21-0
Research Areas:  

Cancer

Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .
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Cat. No.: HY-111355B
CAS No.: 2864-50-8
Purity:  98.22%
Cholesterol sulfate sodium is a naturally occurring, orally active cholesterol derivative that is widely distributed in various tissues and body fluids. Cholesterol sulfate sodium acts as a DOCK2 inhibitor, with IC50 values of 2 μM and 2.9 μM against mouse and human targets, respectively. Cholesterol sulfate sodium restricts excessive neutrophil infiltration and alleviates intestinal inflammation and damage. Cholesterol sulfate sodium serves as an activator of protein kinase C (PKC), which promotes squamous cell differentiation and inhibits skin carcinogenesis. Cholesterol sulfate sodium regulates cholesterol homeostasis and cellular metabolism by activating the AMPK-Sirt1 pathway. Cholesterol sulfate sodium can be used in research related to actinic keratitis, ulcerative colitis, skin cancer, and other conditions .
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Cat. No.: HY-18778
CAS No.: 866399-87-3
Synonyms: TA-8995; DEZ-001; AMG-899
Research Areas:  

Cardiovascular Disease

Obicetrapib (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .
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Cat. No.: HY-113463
CAS No.: 74892-97-0
Purity:  ≥99.0%
Synonyms: CE(20:5(5Z,8Z,11Z,14Z,17Z)
Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC50 values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities .
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Cat. No.: HY-107823
CAS No.: 604-35-3
Purity:  99.41%
Synonyms: Cholesterol 3-acetate; Cholesterin acetate; Cholesterol 3β-acetate
Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester that is exported from Saccharomyces cerevisiae via a Pry1-dependent mechanism. Cholesteryl acetate binds to the CAP superfamily protein Pry1 via interactions dependent on Pry1’s caveolin-binding motif .
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Cat. No.: HY-113369
CAS No.: 604-34-2
Purity:  99.20%
Cholesteryl arachidonate is an endogenous metabolite.
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Cat. No.: HY-N2338
CAS No.: 1989-52-2
Synonyms: Cholesteryl myristate; Cholesteryl tetradecanoate
Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.
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Cat. No.: HY-W010697
CAS No.: 604-33-1
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.
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Cat. No.: HY-W010708
CAS No.: 601-34-3
Cholesteryl palmitate is the main cholesterol ester found in human blephariol and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eye syndrome. Cholesteryl palmitate can be used as a predictor of fetal lung maturity. Cholesteryl palmitate can be used as a prognostic biomarker for chronic interstitial pneumonia .
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Cat. No.: HY-133961
CAS No.: 7073-61-2
Synonyms: Cholesteryl glucoside
Target:  

HSP

Research Areas:  

Metabolic Disease

Cholesterol β-D-glucoside (Cholesteryl glucoside) is a heat shock transcription factor 1 (HSF1) activator. Cholesterol β-D-glucoside induces HSP70 in fibroblast cells .
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Cat. No.: HY-P2879A
CAS No.: 9026-00-0
Research Areas:  

Metabolic Disease

Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesteryl esters into cholesterol and free fatty acids in the intestine. Cholesterol esterase, also known as bile salt-stimulated lipase or carboxyl ester lipase, functions to promote cholesterol absorption .
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Cat. No.: HY-12089
CAS No.: 262352-17-0
Purity:  99.88%
Synonyms: CP-529414
Target:  

CETP

Research Areas:  

Endocrinology

Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .
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Cat. No.: HY-W010695
CAS No.: 35602-69-8
Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.
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Cat. No.: HY-160155
CAS No.: 1391826-58-6
Research Areas:  

Others

Cholesteryl-Teg azide is a cholesterol azide and can be used as a ligand for bioconjugation. Cholesteryl-Teg azide can modify RNA strands .
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Cat. No.: HY-113170
CAS No.: 2573-03-7
Synonyms: Cholesteryl arachidate
Research Areas:  

Metabolic Disease

CE(20:0) (Cholesteryl arachidate) is an ester product.
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Cat. No.: HY-149037A
Purity:  98.60%
Synonyms: N4-Spermine Cholesteryl carbamate pentahydrochloride
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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