2. Metabolic Enzyme/Protease Immunology/Inflammation
  3. Endogenous Metabolite COX
  4. Cholesteryl eicosapentaenoate

Cholesteryl eicosapentaenoate  (Synonyms: CE(20:5(5Z,8Z,11Z,14Z,17Z))

Cat. No.: HY-113463 Purity: 99.9%
COA
SDS
Handling Instructions Technical Support

Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC50 values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities.

For research use only. We do not sell to patients.

Cholesteryl eicosapentaenoate

Cholesteryl eicosapentaenoate Chemical Structure

CAS No. : 74892-97-0

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Cholesteryl eicosapentaenoate Related Antibodies

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Description

Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC50 values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

COX-1

14.6 μg/mL (IC50)

COX-2

17.3 μg/mL (IC50)

In Vitro

At 25 μg/mL concentration, Cholesteryl eicosapentaenoate inhibits lipid peroxidation (LPO) by 72%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cholesteryl eicosapentaenoate Related Antibodies
Molecular Weight

671.09

Formula

C47H74O2
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H](CCCC(C)C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: 99.9%

SDS (251 KB)

COA (247 KB)

Handling Instructions (2659 KB)
References
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Cholesteryl eicosapentaenoate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholesteryl eicosapentaenoate74892-97-0CE(20:5(5Z,8Z,11Z,14Z,17Z)Endogenous MetaboliteCOXCyclooxygenaseCOX-1/COX-2 Inhibitoranti-inflammatoryantioxidant activitieslipid peroxidation (LPO)Inhibitorinhibitorinhibit

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