9 Results for "

Combretastatin A 4

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Combretastatin A 4" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N2146
CAS No.: 117048-59-6
Synonyms: CRC 87-09
Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
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Cat. No.: HY-17449
CAS No.: 168555-66-6
Synonyms: CA 4DP; CA 4P; Combretastatin A4 disodium phosphate
Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis .
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Cat. No.: HY-15855
CAS No.: 404886-32-4
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis .
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Cat. No.: HY-N2146R
CAS No.: 117048-59-6
Synonyms: CRC 87-09 (Standard)
Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
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Cat. No.: HY-14815
CAS No.: 222030-63-9
Synonyms: Combretastatin A4 phosphate
Research Areas:  

Cancer

Fosbretabulin (Combretastatin A4 phosphate) is a vascular disruptor with antitumor activity against atypical thyroid carcinoma (ATC) cell lines and xenografts. Fosbretabulin inhibits tumor growth by inhibiting microtubule polymerization, inducing apoptosis, and suppressing angiogenesis in tumors .
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Cat. No.: HY-146506
CAS No.: 1067880-31-2
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

isoCA-4, a Combretastatin A4 derivative, is a tubulin polymerization inhibitor. isoCA-4 has anti-proliferative activities .
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Cat. No.: HY-W007614
CAS No.: 351-54-2
Synonyms: 3-Fluoro-para-anisaldehyde
3-Fluoro-4-methoxybenzaldehyde (3-Fluoro-para-anisaldehyde) is a drug intermediate that can be used to synthesize the fluorinated derivative of Combretastatin A-4 (HY-N2146), which has anti-cancer activity.
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Cat. No.: HY-149021
CAS No.: 2481404-89-9
Research Areas:  

Cancer

Tubulin polymerization-IN-28 (compound-4) is a microtubule protein polymerization inhibitor with highly selective anticancer activity. Tubulin polymerization-IN-28 can be activated by NQO1 and effectively release combretastatin A-4 to kill tumor cells. Tubulin polymerization-IN-28 can induce cell apoptosis and be used in anti-cancer research .
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Cat. No.: HY-W275793
CAS No.: 139-45-7
Synonyms: Glycerol tripropionate
Research Areas:  

Others

Tripropionin (Glycerol tripropionate) is a triglyceride that can be hydrolyzed by carboxylic esterase from carrots. Tripropionin can serve as the oil phase for constructing high-performance lipid nanoemulsion droplets, enabling efficient encapsulation of Combretastatin A4 (HY-N2146) to achieve its stable storage and controlled release .
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