15 Results for "

Cysteamine

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Cysteamine" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-124476
CAS No.: 51-85-4
Purity:  99.79%
Research Areas:  

Cancer

Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .
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7
7 Publications Verification
Cat. No.: HY-W020050
CAS No.: 56-17-7
Research Areas:  

Neurological Disease Cancer

Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .
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4
4 Cited Publications
Cat. No.: HY-101794
CAS No.: 106139-15-5
Purity:  99.93%
Synonyms: (S)-2-Pyridylthio Cysteamine Hydrochloride
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.
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2
2 Cited Publications
Cat. No.: HY-77591
CAS No.: 156-57-0
Synonyms: 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride
Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
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Cat. No.: HY-77591S
CAS No.: 1219805-04-5
Synonyms: 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride
Cysteamine-d4 (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
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Cat. No.: HY-P4119
CAS No.: 863608-35-9
Research Areas:  

Others

Pep-1-Cysteamine is an amphipathic chimeric cell-penetrating peptide. Pep-1-Cysteamine can penetrate biological membranes in an energy-independent manner without forming transmembrane pores, and efficiently deliver active proteins into cells, with its translocation dominated by electrostatic interactions and membrane perturbation .
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Cat. No.: HY-153340
CAS No.: 311343-11-0
Purity:  98.78%
Target:  

Keap1-Nrf2

Research Areas:  

Metabolic Disease

I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .
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Cat. No.: HY-77591R
CAS No.: 156-57-0
Synonyms: 2-Aminoethanethiol hydrochloride (Standard); 2-Mercaptoethylamine hydrochloride (Standard)
Cysteamine (hydrochloride) (Standard) is the analytical standard of Cysteamine (hydrochloride). This product is intended for research and analytical applications. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
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Cat. No.: HY-P1341
CAS No.: 343268-91-7
Synonyms: Orexin A (17-33) (human, mouse, rat, bovine)
OXA (17-33) (Orexin A (17-33) (human, mouse, rat, bovine)) is the shortest active orexin peptide that selectively targets OX1 (EC50=8.29 nM), with 23-fold selectivity for the OX1 receptor over the OX2 receptor. The activity of OXA (17-33) depends on the Tyr17, Leu20, Asn25, His26 residues and the spatial conformation of the α-helix. OXA (17-33) activates signaling pathways involving inositol-1,4,5-trisphosphate receptor (IP3R), phospholipase D (PL-D) and choline-Sigma-1R, thereby increasing the cytoplasmic Ca 2+ level in nucleus accumbens neurons, an effect that is blocked by Sigma-1R antagonists. OXA (17-33) serves as an important biological probe for investigating the function of the OX1 receptor. OXA (17-33) can be modified via incorporation of mixed disulfide bonds of homocysteine and cysteamine, and is widely used in studies related to insomnia and narcolepsy .
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Cat. No.: HY-P4119A
Target:  

Peptides

Research Areas:  

Others

Pep-1-Cysteamine TFA is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine TFA has the ability to translocate across biological membranes and introduce active proteins inside cells .
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Cat. No.: HY-W141781
CAS No.: 3724-89-8
Synonyms: Cystaphos sodium
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant .
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Cat. No.: HY-126751
CAS No.: 331686-58-9
Target:  

Na+/K+ ATPase

Research Areas:  

Metabolic Disease

DBM-819 is a reversible inhibitor of H⁺/K⁺-ATPase (H +/K +-ATPase), with an IC50 value of 5 μM. DBM-819 can reversibly block gastric acid secretion by inhibiting the proton pump in the gastric mucosa. It shows significant protective effects against duodenal ulcers induced by Cysteamine (HY-77591), gastric ulcers induced by Indomethacin (HY-14397), and gastric ulcers induced by Aspirin (HY-14654), with EC50 values of 6, 3.1, and 4 mg/kg respectively. DBM-819 can be used in ulcer prevention research .
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Cat. No.: HY-W020050S
CAS No.: 2712126-51-5
Cystamine-d8 (dihydrochloride) is the deuterium labeled Cystamine (dihydrochloride) . Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .
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Cat. No.: HY-101794R
CAS No.: 106139-15-5
Synonyms: (S)-2-Pyridylthio Cysteamine Hydrochloride (Standard)
2-(Pyridyldithio)ethylamine hydrochloride (Standard) ((S)-2-Pyridylthio Cysteamine Hydrochloride (Standard)) is the analytical standard of 2-(Pyridyldithio)ethylamine hydrochloride (HY-101794). This product is intended for research and analytical applications. 2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.
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Cat. No.: HY-105433
CAS No.: 96413-13-7
Target:  

Drug Derivative

Research Areas:  

Cancer

Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia .
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