58 Results for "

D6D

" in MedChemExpress (MCE) Product Catalog:
Products (58)

58 Results for "D6D" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-107410
CAS No.: 218136-59-5
Purity:  99.66%
Research Areas:  

Inflammation/Immunology

SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties .
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2
2 Cited Publications
Cat. No.: HY-117427
CAS No.: 1236767-85-3
Purity:  99.90%
Research Areas:  

Metabolic Disease

D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice .
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1
1 Cited Publications
Cat. No.: HY-124346
CAS No.: 1356354-09-0
Purity:  99.80%
Research Areas:  

Metabolic Disease

T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay .
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Cat. No.: HY-P3668
CAS No.: 52671-12-2
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist .
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Cat. No.: HY-W017018S
CAS No.: 347841-40-1
L-Ornithine-d6 hydrochloride is the d6-labeled L-Ornithine hydrochloride (HY-W017018). L-Ornithine hydrochloride is an orally active CaSR and p38 activator. L-Ornithine hydrochloride inhibits ROS and supports urea cycle function. L-Ornithine hydrochloride can be used to study kidney diseases involving proximal tubular cell damage caused by oxidative stress or crystallopathy, as well as research related to anxiety disorders .
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Cat. No.: HY-Y0124S
CAS No.: 50348-93-1
Synonyms: α,α-Dimethylglycine-d6; α-Aminoisobutanoic acid-d6
NSC 16590-d6 is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.
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Cat. No.: HY-110231
CAS No.: 1002347-71-8
Purity:  99.6%
Synonyms: MK 733-d6
Simvastatin-d6 (MK 733-d6) is the deuterium labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
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Cat. No.: HY-P3668A
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

[D-Lys6]-LH-RH TFA is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH TFA acts as a GnRH receptor agonist .
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Cat. No.: HY-W048995
CAS No.: 72002-30-3
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

D-6-Oxo-pipecolinic acid is the D-enantiomer of 6-Oxo-pipecolinic acid. 6-Oxo-pipecolinic acid is the biomarkers associated with pyridoxine-dependent epilepsy (PDE-ALDH7A1) .
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Cat. No.: HY-17504AS1
CAS No.: 2070009-40-2
Synonyms: ZD 4522-d6
Rosuvastatin-d6 (ZD 4522-d6) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
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Cat. No.: HY-RS04667
Research Areas:  

Others

FADS2 Human Pre-designed siRNA Set A contains three designed siRNAs for FADS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-W105506S
CAS No.: 1246274-70-3
Synonyms: s,s-Dimethyl-β-propionic acid thetine-d6
Dimethylpropiothetin hydrochloride-d6 (s,s-Dimethyl-β-propionic acid thetine-d6) is the d6-labeled Dimethylpropiothetin hydrochloride (HY-W105506). Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure .
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Cat. No.: HY-10261S
CAS No.: 1313874-96-2
Purity:  ≥99.0%
Synonyms: BIBW 2992 d6
Afatinib-d6 (BIBW 2992-d6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor .
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Cat. No.: HY-Y0504S4
CAS No.: 347840-14-6
Synonyms: Hegzadesil-d6; Trimethylamine hydrochloric acid-d6; Trimethylamine monohydrochloride-d6
Trimethylammonium chloride-d6 (Hegzadesil-d6) is the d6-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-11018S2
CAS No.: 1225444-65-4
Synonyms: R 64 766-d6
Risperidone-d6 (R 64 766-d6) is the deuterium labeled Risperidone (HY-11018). Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively .
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Cat. No.: HY-W050088S
CAS No.: 2012598-71-7
Synonyms: HP 549-d6
Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088). Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases .
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Cat. No.: HY-107410R
CAS No.: 218136-59-5
SC-26196 (Standard) is the analytical standard of SC-26196 (HY-107410). This product is intended for research and analytical applications. SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties .
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Cat. No.: HY-13511S
Synonyms: UR-12592-d6
Rupatadine-d6 (D-tartrate) is deuterated labeled Rupatadine (HY-13511). Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria .
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Cat. No.: HY-18318
CAS No.: 1125632-93-0
Target:  

Raf VEGFR PERK

Research Areas:  

Cancer

Takeda-6D (compound 6d) is an orally active and potent BRAF/VEGFR2 inhibitor, with IC50 values of 7.0 and 2.2 nM, respectively. Takeda-6D shows antiangiogenesis by suppressing the VEGFR2 pathway in 293/KDR and VEGF-stimulated HUVEC cells.Takeda-6D shows significant suppression of ERK1/2 phosphorylation. Takeda-6D shows antitumor activity .
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Cat. No.: HY-W021399S
Lidocaine impurity 5-d6 is deuterium labeled Lidocaine impurity 5.
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