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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
DTT
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "DTT" in MCE Product Catalog:
49
49 Publications Verification
Synonyms: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
3
3 Cited Publications
Cat. No.: HY-15917A
CAS No.: 16096-97-2
2
2 Cited Publications
Synonyms: Dithioerythritol; Cleland’s reagent
Cat. No.: HY-W106411
CAS No.: 71865-37-7
Synonyms: Dithio-bis-maleimidoethane
Target:
Research Areas:
DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT (HY-15917). DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions .
Cat. No.: HY-15917S2
CAS No.: 850153-85-4
Synonyms: DTT-d6
Cat. No.: HY-D2315
Cat. No.: HY-15917S
CAS No.: 302912-05-6
Synonyms: DTT-d10
Cat. No.: HY-W800651
CAS No.: 2098496-90-1
Target:
Research Areas:
Biotin-SS-Amine hydrochloride is a cleavable biotinylation reagent. The amine group can react with carboxylic acids, activated NHS esters and other carbonyl groups. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP.
Cat. No.: HY-15917S1
CAS No.: 203633-21-0
Synonyms: DTTl-d10-1
Cat. No.: HY-144793
Target:
Research Areas:
Deac-SS-Biotin is a potent antitumor agent with improved tumor targeting effects and reduced off-target toxicities. Deac-SS-Biotin uptakes into the cells through biotin-mediated internalization. Deac-SS-Biotin combined with DTT (Glutathione mimetic) can effectively inhibit microtubule assembly and displays greater antitumor activity .
Cat. No.: HY-W024229
CAS No.: 502764-53-6
Synonyms: DTT-2,6-dicarboxylic acid
Dithieno[3,2-b:2',3'-d]thiophene-2,6-dicarboxylic acid(DTT-2,6-dicarboxylic acid) is a metal-organic framework (MOF).
Cat. No.: HY-W190940
CAS No.: 1380166-80-2
Cat. No.: HY-134800
CAS No.: 692744-81-3
IBT21 is an endoplasmic reticulum stress inhibitor that binds to unfolded or misfolded proteins and prevents their aggregation. IBT21 inhibits UPR activation of the ATF6, IRE1 and PERK branches under ER stress, with IC50 values of 0.24 μM, 0.33 μM, and 0.46 μM, respectively. IBT21 protects cells from ER stress-induced death and mutant prion protein (protein toxin)-induced growth inhibition. IBT21 exhibits chemical chaperone activity distinct from UPR modulators, does not affect protein translation, moderately reduces DTT (HY-15917)-induced ER stress, and fails to inhibit the heat shock response. IBT21 is useful for research related to prion diseases .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
