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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
EPHB1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "EPHB1" in MCE Product Catalog:
1
EphB1-IN-1 (Compound 1) is a potent EphB1 inhibitor with IC50s of 3.0, 15 and 220 nM against EphB1 G703C, EphB1 T697G and EphB1 WT, respectively [1].
Cat. No.: HY-170517
CAS No.: 3065631-84-4
Target:
Research Areas:
PKMYT1-IN-8 (Compound 137) is the inhibitor for PKMYT1 with an IC50 of 9 nM. PKMYT1-IN-8 inhibits EPHB3, EPHA1, KIT, EPHB1, EPHA2, EPHA3, and EPHB2with IC50s of 1.79, 3.17, 4.29, 6.32, 6.83, 8.10, and 10.9 μM, respectively. PKMYT1-IN-8 inhibits the proliferation of cancer cell OVCAR3 with GI50 of 2.02 μM [1].
Cat. No.: HY-RS04433
Target:
Research Areas:
EPHB1 Human Pre-designed siRNA Set A contains three designed siRNAs for EPHB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18062
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Research Areas:
Ephb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ephb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24537
Target:
Research Areas:
Ephb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ephb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183909
CAS No.: 2097512-73-5
EphB1-IN-2 is a mutant-selective kinase inhibitor of ABL and FGFR4, with an IC50 of 14 nM against ABL G321C mutant and 163 nM against FGFR4 G556C mutant. EphB1-IN-2 shows selectively over wild-type ABL and FGFR4 [1] .
Cat. No.: HY-P77360
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-B receptor 1; ELK; EK6; NET; EPHB1; EPHT2; HEK6
Species:
Source:
Cat. No.: HY-P77359
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-B receptor 1; ELK; EK6; NET; EPHB1; EPHT2; HEK6
Species:
Source:
Cat. No.: HY-P75747
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-B receptor 1; ELK; EK6; NET; EPHB1; EPHT2; HEK6
Species:
Source:
Cat. No.: HY-P72997
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ephrin type-B receptor 1; ELK; EK6; NET; EPHB1; EPHT2; HEK6
Species:
Source:
Cat. No.: HY-P702709
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: EPHB1; EPH receptor B1; EPHB1 , EPHT2; ephrin type-B receptor 1; Hek6; EK6; EPH-like kinase 6; eph tyrosine kinase 2; soluble EPHB1 variant 1; tyrosine-protein kinase receptor EPH-2; neuronally-expressed EPH-related tyrosine kinase; ELK; NET; EPHT2; FLJ37986
Cat. No.: HY-P70381
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuEphrin type-B receptor 1/EPHB1, Fc; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6
Cat. No.: HY-P705819
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: rHuEphrin Type-B Receptor 1/EPHB1, His; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6
Cat. No.: HY-179572
Target:
Research Areas:
STA-013 is a EphB tyrosine kinase inhibitor. STA-013 shows promising potency against EphB1 (IC50 = 0.69 µM), EphB2 (IC50 = 1.73 µM), and EphB4 (IC50 = 1.02 µM) tyrosine kinases. STA-013 results a inhibition of the EphB phosphorylated signal, coupled with increased p-AKT/AKT signaling, to suggest insulin signaling activation. STA-013 inhibits EphB tyrosine kinase by enhancing insulin receptor beta (IRβ) signaling, and decreasing TGF-β levels in the heart. STA-013 can be used for the study of type 2 diabetes and cardiac complications (diabetic cardiomyopathy) [1].
Cat. No.: HY-P85145
Synonyms: EPHB1; ELK; EPHT2; HEK6; NET; Ephrin type-B receptor 1; ELK; EPH tyrosine kinase 2; EPH-like kinase 6; EK6; hEK6; Neuronally-expressed EPH-related tyrosine kinase; NET; Tyrosine-protein kinase receptor EPH-2
Cat. No.: HY-P82431
Synonyms: EPHB1; ELK; EPHT2; HEK6; NET; Ephrin type-B receptor 1; ELK; EPH tyrosine kinase 2; EPH-like kinase 6; EK6; hEK6; Neuronally-expressed EPH-related tyrosine kinase; NET; Tyrosine-protein kinase receptor EPH-2
Cat. No.: HY-183103
CAS No.: 2222129-13-5
PDD-87 is an orally active, blood-brain barrier permeable kinase inhibitor, with IC50 values ranging from 0.07 nM to 0.72 nM against ABL, SRC family, BTK kinases and their key mutants. PDD-87 induces antiproliferative effects in leukemia and lymphoma cells, and inhibits tumor growth in mouse xenograft models. PDD-87 can be used for the research of leukemia and lymphoma [1].
Cat. No.: HY-10654
CAS No.: 1192216-03-7
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Research Areas:
EphB4-IN-2 is a tyrosine kinase inhibitor targeting the Eph family and Src family. EphB4-IN-2 binds to the ATP-binding site of the kinase domain of EphB4, and exhibits high affinity for tyrosine kinases with threonine as the gatekeeper residue, such as Abl, Lck and Src. EphB4-IN-2 can be used in research related to tumor-associated angiogenesis [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
