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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Ellipticine
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Ellipticine" in MCE Product Catalog:
5
Category:
Apocynaceae Alkaloids Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Cancer Indole Alkaloids
Target:
5
5 Cited Publications
Synonyms: NSC 71795 hydrochloride
Category:
Apocynaceae Alkaloids Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Cancer Indole Alkaloids
Target:
Cat. No.: HY-141878
CAS No.: 2767983-76-4
Target:
Research Areas:
di-Ellipticine-RIBOTAC is a RNase recruiting chimera (RIBOTAC) degrader, capable of specifically binding and degrading expanded G4C2 RNA repeat (r(G4C2) exp). di-Ellipticine-RIBOTAC selectively binds the three-dimensional (3D) structure formed by r(G4C2) exp and that recruits an endogenous ribonuclease (RNase) to cleave r(G4C2) exp. di-Ellipticine-RIBOTAC selectively degrades the mutant chromosome 9 open reading frame 72 (C9orf72) allele and reduces quantities of toxic dipeptide repeat proteins (DPRs) translated from r(G4C2) exp. di-Ellipticine-RIBOTAC significantly improves the pathological phenotype of amyotrophic lateral sclerosis/ frontotemporal dementia (c9ALS/FTD) in cells and mouse models. di-Ellipticine-RIBOTAC can be used for the study of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) .
Cat. No.: HY-U00337
CAS No.: 105118-14-7
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Research Areas:
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.
Cat. No.: HY-177872
CAS No.: 501662-77-7
Synonyms: NSC 338258
Target:
Research Areas:
GQC-05 (NSC338258), Ellipticine (HY-15753) derivative, is potent and selective c-Myc G-quadruplex ( c-Myc G4) stabilizer with KD values of 0.1-1.43 μM. GQC-05 can reduce Myc expression and induce cancer cells apoptosis. GQC-05 can be used for the research of cancer, such as Burkitt lymphoma .
Cat. No.: HY-15753AR
CAS No.: 5081-48-1
Synonyms: NSC 71795 hydrochloride (Standard)
Category:
Apocynaceae Alkaloids Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Indole Alkaloids
Target:
Category:
Apocynaceae Alkaloids Marine natural products Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Indole Alkaloids
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Cat. No.: HY-141878A
CAS No.: 2767983-77-5
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Research Areas:
di-Ellipticine-RIBOTAC TFA is a RNase recruiting chimera (RIBOTAC) degrader, capable of specifically binding and degrading expanded G4C2 RNA repeat (r(G4C2) exp). di-Ellipticine-RIBOTAC TFA selectively binds the three-dimensional (3D) structure formed by r(G4C2) exp and that recruits an endogenous ribonuclease (RNase) to cleave r(G4C2) exp. di-Ellipticine-RIBOTAC TFA selectively degrades the mutant chromosome 9 open reading frame 72 (C9orf72) allele and reduces quantities of toxic dipeptide repeat proteins (DPRs) translated from r(G4C2) exp. di-Ellipticine-RIBOTAC TFA significantly improves the pathological phenotype of amyotrophic lateral sclerosis/ frontotemporal dementia (c9ALS/FTD) in cells and mouse models. di-Ellipticine-RIBOTAC TFA can be used for the study of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) .
Cat. No.: HY-U00337A
CAS No.: 157000-76-5
Target:
Research Areas:
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors .
Cat. No.: HY-106307
CAS No.: 72238-02-9
Synonyms: BD84
Target:
Research Areas:
Retelliptine (BD84), a derivative of ellipticine, is an inhibitor of Topoisomerase II with anticancer activity. Retelliptine can bind to DNA and inhibit Topoisomerase II during DNA replication .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
