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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
GPR30
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "GPR30" in MCE Product Catalog:
143
143 Publications Verification
Synonyms: ICI 182780; ZD 9238; ZM 182780
Target:
Research Areas:
Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
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42 Cited Publications
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G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM .
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30 Cited Publications
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G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
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1
Target:
Target:
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G-36 is a cell-permeable nonsteroidal antagonist of the G protein-coupled estrogen receptor (GPER/GPR30), which selectively inhibits estrogen-mediated PI3K activation through GPER, rather than Erα. G-36 also inhibits estrogen-mediated calcium mobilization (IC50=112 nM). G-36 is promising for research in the field of cancer .
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GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects .
Synonyms: ICI 182780(Standard); ZD 9238(Standard); ZM 182780 (Standard)
Research Areas:
Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
Cat. No.: HY-13636S
Purity: 97.47%
Synonyms: ICI 182780-d3; ZD 9238-d3; ZM 182780-d3
Cat. No.: HY-13636S1
Synonyms: ICI 182780-d5; ZD 9238-d5; ZM 182780-d5
Cat. No.: HY-RS05636
Target:
Research Areas:
GPER1 Human Pre-designed siRNA Set A contains three designed siRNAs for GPER1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-107216A
CAS No.: 925419-53-0
Research Areas:
(3aS,4R,9bR)-G-1 is a highly selective G protein-coupled receptor GPR30 (GPER) agonist with a Ki value of approximately 7 nM. (3aS,4R,9bR)-G-1 activates rapid signaling pathways such as intracellular calcium mobilization and PI3K signaling through GPR30, promoting uterine epithelial cell proliferation and exerting antidepressant effects. (3aS,4R,9bR)-G-1 is promising for research of breast cancer and depression .
Cat. No.: HY-107216R
CAS No.: 881639-98-1
Research Areas:
G-1 (Standard) is the analytical standard of G-1 (HY-107216). This product is intended for research and analytical applications. G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
Cat. No.: HY-103449R
CAS No.: 1161002-05-6
Research Areas:
G15 (Standard) is the analytical standard of G15 (HY-103449). This product is intended for research and analytical applications. G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM .
Cat. No.: HY-RS25000
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Gper1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gper1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-103450R
CAS No.: 1392487-51-2
Research Areas:
G36 (Standard) is the analytical standard of G36 (HY-103450). This product is intended for research and analytical applications. G-36 is a cell-permeable nonsteroidal antagonist of the G protein-coupled estrogen receptor (GPER/GPR30), which selectively inhibits estrogen-mediated PI3K activation through GPER, rather than Erα. G-36 also inhibits estrogen-mediated calcium mobilization (IC50=112 nM). G-36 is promising for research in the field of cancer .
Cat. No.: HY-P81150
Synonyms: G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymphocyte-derived G-protein coupled receptor; LYGPR; GPCR-BR; CEPR; CMKRL2; DRY12; GPER.
Cat. No.: HY-RS18518
Target:
Research Areas:
Gper1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gper1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
