14 Results for "

HPP

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "HPP" in MCE Product Catalog:

Cat. No.: HY-108786
CAS No.: 1174277-80-5
Purity:  97.88%
Synonyms: ENB-0040

Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .
loading...
    loading...
Cat. No.: HY-112597A
CAS No.: 1604815-32-8
Purity:  99.89%
Synonyms: REN001; HPP593
Target:  

PPAR

Research Areas:  

Inflammation/Immunology

Mavodelpar (REN001) is a selective PPARδ agonist. Mavodelpar suppresses glomerular injury and renal fibrosis. Mavodelpar can be used for the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD) . Mavodelpar is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
Cat. No.: HY-156814
CAS No.: 3093738-79-2
Target:  

Hedgehog

Research Areas:  

Cancer

HPP-9 is a Proteolysis-Targeting Chimeras (PROTACs) based on Hedgehog Pathway Inhibitor-1 (HPI-1), with the pIC50 of 6.71, that can degrade BET bromodomains. HPP-9 has antitumor activity [1[.
loading...
    loading...
Cat. No.: HY-P991210
CAS No.: 2746354-58-3
Synonyms: ALXN-1850

Target:  

Phosphatase

Research Areas:  

Cardiovascular Disease

Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
loading...
    loading...
Cat. No.: HY-114545
CAS No.: 105624-86-0
Research Areas:  

Cancer

5HPP-33 is an inhibitor for tubulin polymerization with IC50 of 8.1 μM. 5HPP-33 inhibits the proliferation of leukemia cell and multiple myeloma cells with IC50 of 1-10 μM, arrests the cell cycle at G2/M phase, and induces apoptosis .
loading...
    loading...
Cat. No.: HY-RS13729
Research Areas:  

Others

SPTA1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPTA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-118768
CAS No.: 302556-51-0
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

FMS586 free base is a selective neuropeptide Y Y5 receptor antagonist with oral activity. FMS586 can completely block the significant increase in adrenocorticotropic hormone (ACTH) and cortisol caused by the Y(5) selective agonist hPP. FMS586 also reversed the significant upregulation of adrenocorticotropic hormone (CRF) and antidiuretic hormone (AVP) mRNA expression induced by central injection of hPP. FMS586 provides the first evidence that selective stimulation of Y(5) receptors triggers activation of the HPA axis .
loading...
    loading...
Cat. No.: HY-112597
CAS No.: 942594-93-6
Synonyms: REN001 free acid; HPP593 free acid; Pparδ agonist
Target:  

PPAR

Research Areas:  

Metabolic Disease

Mavodelpar free acid is a PPARδ agonist extracted from patent US20180071304, compound example 10. Mavodelpar (free acid) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
Cat. No.: HY-P88846
Synonyms: CT120.2; HPP1; TENB2; TPEF; TR; TR-2

Host:  

Mouse

Application:  

ICC/IF, FC

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-P88846A
Synonyms: CT120.2; HPP1; TENB2; TPEF; TR; TR-2

Host:  

Mouse

Application:  

ICC/IF, FC

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-P82290
Synonyms: TMEFF2; HPP1; TPEF; TR-2; Tomoregulin; TENB2; Tomoregulin-2; CT120.2

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P82386
Synonyms: NEDD8 activating enzyme E1 subunit 1; HPP1; ula-1; APPBP1; A-116A10.1

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P82386A
Synonyms: NEDD8 activating enzyme E1 subunit 1; HPP1; ula-1; APPBP1; A-116A10.1

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P700470
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TMEFF2; transmembrane protein with EGF like and two follistatin like domains 2; TR; HPP1; TPEF; TR-2; TENB2; CT120.2; tomoregulin-2; cancer/testis antigen family 120, member 2; hyperplastic polyposis protein 1; transmembrane protein TENB2; transmembrane protein with EGF-like and two follistatin-like domains
Species:  
Source:  
loading...
    loading...
  • 1