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Results for "

HePTP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (1) ERK (1) Phosphatase (7) Small Interfering RNA (siRNA) (4) Tyrosinase (1)
By Research Areas:	Cancer (6) Inflammation/Immunology (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-178297

VHR-IN-7	Phosphatase	Cancer
VHR-IN-7 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC₅₀ of 71 nM. VHR-IN-7 shows very weaker inhibitory activity against MKP-1 (IC₅₀ = 0.47 μM), CD45 (IC₅₀ = 0.3 μM), Cdc25A (IC₅₀ = 3.4 μM), PTP1B (IC₅₀ = 0.59 μM), and HePTP (IC₅₀ = 1.2 μM). VHR-IN-7 inhibits the proliferation of HeLa cells. VHR-IN-7 can be used for the research of cervical cancer .

HY-178296

VHR-IN-6	Phosphatase	Cancer
VHR-IN-6 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC₅₀ of 74 nM. VHR-IN-6 shows very weaker inhibitory activity against MKP-1 (IC₅₀ = 0.52 μM), CD45 (IC₅₀ = 0.50 μM), Cdc25A (IC₅₀ = 2.8 μM), PTP1B (IC₅₀ = 0.42 μM), and HePTP (IC₅₀ = 0.87 μM). VHR-IN-6 inhibits the proliferation of HeLa cells. VHR-IN-6 can be used for the research of cervical cancer .

HY-178301

VHR-IN-9	Phosphatase	Cancer
VHR-IN-9 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC₅₀ of 270 nM. VHR-IN-9 shows very weaker inhibitory activity against MKP-1 (IC₅₀ = 2.8 μM), CD45 (IC₅₀ = 1.8 μM), Cdc25A (IC₅₀ = > 10 μM), PTP1B (IC₅₀ = 2.2 μM), and HePTP (IC₅₀ = 2.4 μM). VHR-IN-9 inhibits the proliferation of HeLa cells. VHR-IN-9 can be used for the research of cervical cancer .

HY-RS24883

Ptpn7 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptpn7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn7 Rat Pre-designed siRNA Set A Ptpn7 Rat Pre-designed siRNA Set A

HY-127178

ML120 analog 1	Phosphatase	Cancer
ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for Hematopoietic protein tyrosine phosphatase (HePTP) .

HY-RS11430

PTPN7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTPN7 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPN7 Human Pre-designed siRNA Set A PTPN7 Human Pre-designed siRNA Set A

HY-RS11432

PTPRA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTPRA Human Pre-designed siRNA Set A contains three designed siRNAs for PTPRA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPRA Human Pre-designed siRNA Set A PTPRA Human Pre-designed siRNA Set A

HY-178295

VHR-IN-5	Phosphatase	Cancer
VHR-IN-5 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC₅₀ of 78 nM. VHR-IN-5 shows very weaker inhibitory activity against MKP-1 (IC₅₀ = 0.78 μM), CD45 (IC₅₀ = 0.61 μM), Cdc25A (IC₅₀ = 3.4 μM), PTP1B (IC₅₀ = 1.8 μM), and HePTP (IC₅₀ = 1.5 μM). VHR-IN-5 inhibits the proliferation of HeLa cells. VHR-IN-5 can be used for the research of cervical cancer .

HY-RS18402

Ptpn7 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptpn7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn7 Mouse Pre-designed siRNA Set A Ptpn7 Mouse Pre-designed siRNA Set A

HY-182634

NCGC00063279	DNA/RNA Synthesis Phosphatase	Cancer
NCGC00063279 is a reversible Werner Syndrome Helicase-Nuclease (WRN) helicase inhibitor with modest selectivity over BLM and FANCJ helicases, and does not inhibit WRN exonuclease activity at active concentrations. NCGC00063279 inhibits Hematopoietic Protein Tyrosine Phosphatase (HePTP) and reduces proliferation of cancer cells. NCGC00063279 can be used for the research of osteosarcoma .

HY-182299

LYP-IN-5	Phosphatase Tyrosinase ERK	Inflammation/Immunology
LYP-IN-5 is a lymphoid tyrosine phosphatase (LYP) inhibitor with an IC₅₀ value of 20.6 μM. LYP-IN-5 enhances the phosphorylation of ZAP70 and ERK1/2 following TCR stimulation, and promotes T cell activation. LYP-IN-5 can be used in the research of autoimmune diseases .

Host:	Mouse (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88909

	*PTPN7 (HePTP) Antibody (YA8593)* BPTP-4; HePTP; LC-PTP; LPTP; PTPNI	IHC-P, ICC/IF	Human, Mouse, Rat
	PTPN7 (HePTP) Antibody (YA8593) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPN7 (HePTP).

HY-P88909A

	*PTPN7 (HePTP) Antibody (YA8593)(PBS only)* BPTP-4; HePTP; LC-PTP; LPTP; PTPNI	IHC-P, ICC/IF	Human, Mouse, Rat
	PTPN7 (HePTP) Antibody (YA8593) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPN7 (HePTP).

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Ptpn7 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ptpn7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPN7 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTPN7 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPRA Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTPRA Human Pre-designed siRNA Set A contains three designed siRNAs for PTPRA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn7 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ptpn7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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