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Isoforms Recommended: IL-17
Results for "

IL17F

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

2

Peptides

1

MCE Kits

6

Inhibitory Antibodies

20

Recombinant Proteins

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99280
    Bimekizumab
    1 Publications Verification

    CDP4940; UCB-4940

    		 Interleukin Related Inflammation/Immunology
    Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation .
    Bimekizumab
  • HY-P1924
    IRBP(651-670) human, mouse

    		Lipocalin Family Interleukin Related Inflammation/Immunology
    IRBP (651-670) human, mouse is an epitope and uveitis inducer naturally processed from the conserved region of native IRBP. IRBP (651-670) human, mouse increases the levels of proinflammatory cytokines in ocular tissues (IL-1β, IL-6, TNFα, IL-17A and IL-17F). IRBP (651-670) human, mouse is a IRBP fragment conserved among human, mouse and bovine species. IRBP (651-670) human, mouse induces experimental autoimmune uveitis. IRBP (651-670) human, mouse is applicable to research related to experimental autoimmune uveitis .
    IRBP(651-670) human, mouse
  • HY-P99397
    Sonelokimab

    ALX 0761; M 1095

    		 Interleukin Related MMP Inflammation/Immunology
    Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .
    Sonelokimab
  • HY-P99424
    Afasevikumab

    RG 7624; RO 5553110; NI-1401

    		 Interleukin Related Inflammation/Immunology
    Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .
    Afasevikumab
  • HY-124686
    ER-464195-01

    		STAT Interleukin Related TNF Receptor Inflammation/Immunology
    ER-464195-01 is an orally active calreticulin (CRT) and integrin α subunits (ITGAs) binding inhibitor. ER-464195-01 inhibits leukocyte infiltration and subsequent inflammatory cascade reactions by dissociating the binding between CRT and ITGA. ER-464195-01 down-regulates the expression of pro-inflammatory genes (such as TNF-α, IL-1β, IL-6, IL-17f) induced by DSS (HY-116282C), and inhibit the phosphorylation of STAT3 and the production of serum amyloid A (SAA). ER-464195-01 can be used for the study of inflammatory bowel disease (IBD) .
    ER-464195-01
  • HY-P990221
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9)

    		Interleukin Related Infection Neurological Disease Cancer
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse IL-17F. Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) can neutralize IL-17. Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) can be used for the researches of cancer, infection and neurological disease, such as Alzheimer’s disease (AD) and pancreatic cancer .
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9)
  • HY-RS17703
    Il17f Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Il17f Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il17f gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il17f Mouse Pre-designed siRNA Set A
    Il17f Mouse Pre-designed siRNA Set A
  • HY-RS06701
    IL17F Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    IL17F Human Pre-designed siRNA Set A contains three designed siRNAs for IL17F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IL17F Human Pre-designed siRNA Set A
    IL17F Human Pre-designed siRNA Set A
  • HY-P1924A
    IRBP(651-670) human, mouse TFA

    		Lipocalin Family Interleukin Related Inflammation/Immunology
    IRBP (651-670) human, mouse TFA is an epitope and uveitis inducer naturally processed from the conserved region of native IRBP. IRBP (651-670) human, mouse TFA increases the levels of proinflammatory cytokines in ocular tissues (IL-1β, IL-6, TNFα, IL-17A and IL-17F). IRBP (651-670) human, mouse TFA is a IRBP fragment conserved among human, mouse and bovine species. IRBP (651-670) human, mouse TFA induces experimental autoimmune uveitis. IRBP (651-670) human, mouse TFA is applicable to research related to experimental autoimmune uveitis .
    IRBP(651-670) human, mouse TFA
  • HY-RS24167
    Il17f Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Il17f Rat Pre-designed siRNA Set A contains three designed siRNAs for Il17f gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il17f Rat Pre-designed siRNA Set A
    Il17f Rat Pre-designed siRNA Set A
  • HY-168971
    Paeoniflorin-6′-O-benzene sulfonate

    CP-25

    		 IFNAR STAT TNF Receptor Interleukin Related CXCR JAK G Protein-coupled Receptor Kinase (GRK) Inflammation/Immunology
    Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .
    Paeoniflorin-6′-O-benzene sulfonate
  • HY-P991146
    Lecankitug

    LZM-012; XKH004

    		 Interleukin Related Inflammation/Immunology
    Lecankitug is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A) and interleukin 17F (IL-17F). Lecankitug specifically binds to IL-17A and IL-17F, blocking their signal transduction, thus exerting immunosuppressive and anti-inflammatory activities. Lecankitug is promising for research of autoimmune and inflammatory diseases, such as psoriasis and rheumatoid arthritis .
    Lecankitug
  • HY-P992236
    Anti-IL-17F Antibody

    		Interleukin Related Inflammation/Immunology
    Anti-IL-17F Antibody is a monoclonal antibody that targets IL-17F. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-17F Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-IL-17F Antibody
  • HY-153276
    Androgen receptor-IN-5

    		Androgen Receptor Cancer
    Androgen receptor-IN-5 is an androgen receptor inhibitor with potent anticancer effects. Androgen receptor-IN-5 also inhibits the production of IL-17A, IL- 17F and INF-γ (WO2023281097A1,Example 1/1) .
    Androgen receptor-IN-5
  • HY-183370
    JAK2/STAT3-IN-2

    		JAK STAT Interleukin Related Inflammation/Immunology
    JAK2/STAT3-IN-2 is an orally active JAK2/STAT3 inhibitor. JAK2/STAT3-IN-2 inhibits the phosphorylation of tyrosine residues in JAK2 and STAT3, blocks downstream signal transduction, disrupts the dimerization and nuclear translocation of STAT3, and suppresses pro-inflammatory transcriptional activity. JAK2/STAT3-IN-2 inhibits the expression of IL-17A and IL-17F, reduces immune cell infiltration, and inhibits the production of NO simultaneously. JAK2/STAT3-IN-2 exerts a protective effect in a mouse model of ulcerative colitis induced by DSS (HY-116282C). JAK2/STAT3-IN-2 can be used for the research of ulcerative colitis .
    JAK2/STAT3-IN-2

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