70 Results for "

IL3

" in MedChemExpress (MCE) Product Catalog:
Products (70)

70 Results for "IL3" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P70576
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3
Species:  
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3
3 Cited Publications
Cat. No.: HY-B1402
CAS No.: 2203-97-6
Synonyms: Hydrocortisone 21-hemisuccinate
Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers [3].
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3
3 Cited Publications
Cat. No.: HY-B1402B
CAS No.: 125-04-2
Synonyms: Hydrocortisone 21-hemisuccinate sodium
Hydrocortisone hemisuccinate sodium is an orally active physiological glucocorticoid. Hydrocortisone hemisuccinate sodium inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate sodium can be used for the research of ulcerative colitis (UC) .
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3
3 Cited Publications
Cat. No.: HY-B1402A
CAS No.: 83784-20-7
Synonyms: Hydrocortisone 21-hemisuccinate hydrate
Hydrocortisone hemisuccinate hydrate (Hydrocortisone 21-hemisuccinate hydrate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate hydrate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate hydrate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers [3].
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3
3 Cited Publications
Cat. No.: HY-P70685
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-3; IL-3; Hematopoietic growth factor; Multipotential colony-stimulating factor; P-cell-stimulating factor; IL3; IL-3; Mast cell growth factor; MCGF
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1
1 Cited Publications
Cat. No.: HY-P99395
CAS No.: 1826831-79-1
Synonyms: JNJ 56022473; CSL 362

Target:  

Interleukin Related

Research Areas:  

Cancer

Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models [3] .
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1
1 Cited Publications
Cat. No.: HY-P70765
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3
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1
1 Cited Publications
Cat. No.: HY-P7040A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
Species:  
Source:  
CHO
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Cat. No.: HY-P99234
CAS No.: 2234335-84-1

Research Areas:  

Cancer

Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate (ADC). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN) .
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Cat. No.: HY-P990094
CAS No.: 2643974-98-3
Synonyms: CSL311

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology

Trabikibart (CSL311) is a specific inhibitor targeting the βc receptor (CSF2RB) that inhibits signal transduction mediated by GM-CSF, IL-5, and IL-3. Trabikibart exhibits significant anti-inflammatory and anti-edema effects, reduces myeloid cell infiltration, and inhibits inflammatory cell survival. Trabikibart also possesses antiviral immune functions, which alleviate pulmonary inflammation, reverse airway dysfunction and fibrosis, and thereby restore impaired pulmonary function. Trabikibart can be used in research on related diseases such as acute respiratory distress syndrome, viral pneumonia, asthma, and chronic rhinosinusitis with nasal polyps [3] .
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Cat. No.: HY-P1111
CAS No.: 222018-18-0
Target:  

Src Interleukin Related

Research Areas:  

Inflammation/Immunology

Lyn peptide inhibitor (YGYRLRRKWEEKIPNP-NH2) is a potent, cell-permeable Lyn kinase inhibitor that inhibits Lyn-coupled signaling pathways associated with the IL-5 receptor while preserving the integrity of other signals. Lyn peptide inhibitor blocks the activation of Lyn and inhibits the binding of Lyn tyrosine kinase to the βc subunit of the IL-3/GM-CSF/IL-5 receptor. Lyn peptide inhibitor can be used in the research of eosinophilic diseases such as asthma and allergy .
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Cat. No.: HY-P991699
CAS No.: 3035710-69-8
Synonyms: AZD9829 antibody; INT-020

Research Areas:  

Cancer

Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML) . The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-B1402R
CAS No.: 2203-97-6
Synonyms: Hydrocortisone 21-hemisuccinate (Standard)
Hydrocortisone hemisuccinate (Standard) is the analytical standard of Hydrocortisone hemisuccinate. This product is intended for research and analytical applications. Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-in ammatory agent (SAID). Hydrocortisone hemisuccinate inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate can be used for the research of ulcerative colitis (UC).
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Cat. No.: HY-RS06751
Research Areas:  

Others

IL3 Human Pre-designed siRNA Set A contains three designed siRNAs for IL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06752
Research Areas:  

Others

Il3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174610
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL3 mRNA encodes the human interleukin 3 (IL3) protein, a potent growth promoting cytokine. IL3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
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Cat. No.: HY-RS06753
Research Areas:  

Others

Il3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-126619
CAS No.: 71968-02-0
Target:  

Bacterial Apoptosis

Research Areas:  

Infection

Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that is initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.2 Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s=0.49 and 1.9 μg/mL, respectively).
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Cat. No.: HY-P990214
Anti-Mouse IL-3 Antibody (MP2-8F8) is an anti-mouse IL-3 IgG1 monoclonal antibody. Anti-Mouse IL-3 Antibody (MP2-8F8) relieves joint inflammation by reducing synovial leukocyte infiltration and cytokine levels. Anti-Mouse IL-3 Antibody (MP2-8F8) can reduce the accumulation of basophils. Anti-Mouse IL-3 Antibody (MP2-8F8) can be used for researches on inflammation or infection conditions such as arthritis and parasitic infections [3].
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Cat. No.: HY-RS06764
Research Areas:  

Others

IL3RA Human Pre-designed siRNA Set A contains three designed siRNAs for IL3RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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