IL6R

By Targets:	Interleukin Related (10) Acyltransferase (2) Apoptosis (1) mRNA (1) Small Interfering RNA (siRNA) (2) STAT (3)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (9)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) mRNA (1) Human Pre-designed siRNA Sets (1) Interleukin & Receptors (1) siRNAs (2)

Targets Recommended: Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9917

Tocilizumab 40+ Cited Publications Anti-Human IL6R, Humanized Antibody; RG-1569; rhPM-1	Interleukin Related	Inflammation/Immunology Cancer
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .

HY-P990211

*Anti-Mouse IL-6R* Antibody (15A7)**	Interleukin Related	Inflammation/Immunology Cancer
Anti-Mouse IL-6R Antibody (15A7) is a rat-derived anti-mouse *IL-6R* IgG2b κ type antibody inhibitor. Anti-Mouse IL-6R Antibody (15A7) blocks IL-6 binding to IL-6Rα and inhibits both IL-6 classic and trans-signaling. Anti-Mouse IL-6R Antibody (15A7) can be used for the researches of cancer and inflammation, such as triple-negative breast cancer .

HY-P99112

Satralizumab RG-6168; SA-237	Interleukin Related	Inflammation/Immunology Cancer
Satralizumab is a humanized monoclonal antibody that targets *IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus*. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research .

HY-P9916

Sarilumab Anti-Human IL6Rα, Human Antibody	Interleukin Related STAT Apoptosis	Inflammation/Immunology Cancer
Sarilumab is a monoclonal antibody targeting *IL6* that binds to *IL6R* and blocks the binding of *IL6, thereby inhibiting the activation of the downstream STAT3* phosphorylation signaling pathway. In tumor cells with active *IL6/STAT3* signaling pathways, Sarilumab induces Apoptosis and inhibits cell growth. Sarilumab is applicable to research related to prostate cancer, lung cancer and rheumatoid arthritis .

HY-P99385

Vobarilizumab ALX-0061	Interleukin Related	Inflammation/Immunology
Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (K_d: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .

HY-P10284

S7	Interleukin Related	Cancer
S7 is an IL-6 receptor antagonist and inhibits the binding between IL-6 and IL-6R. S7 can inhibit angiogenesis and tumor growth .

HY-177063

IL-6-IN-2	Interleukin Related	Infection Inflammation/Immunology
IL-6-IN-2 is an *interleukin-6* (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via π-π, π-alkyl, hydrogen bond, and hydrophobic interactions to block *IL-6/IL-6R* heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19 .

HY-P99702

Levilimab BCD-089	Interleukin Related	Inflammation/Immunology
Levilimab (BCD-089) is a fully humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody. Levilimab is an inflammation-alleviating antibody. Levilimab can be used for the research of rheumatoid .

HY-RS06777

IL6R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL6R Human Pre-designed siRNA Set A contains three designed siRNAs for IL6R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL6R Human Pre-designed siRNA Set A IL6R Human Pre-designed siRNA Set A

HY-RS23587

Il6r Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il6r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il6r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il6r Rat Pre-designed siRNA Set A Il6r Rat Pre-designed siRNA Set A

HY-174599

*Human IL6R* mRNA**	mRNA	Inflammation/Immunology
Human IL6R mRNA encodes the human interleukin 6 receptor (IL6R) protein, a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response.

HY-P991602

NI-1201 TZLS-501	Interleukin Related	Cancer
NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both *IL-6* cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R .

HY-P991519

VDJ001	Interleukin Related	Inflammation/Immunology
VDJ001 is a high-affinity humanized anti-IL-6R monoclonal antibody. VDJ001 can be used for the study of rheumatoid arthritis .

HY-182273

DM243	STAT Acyltransferase	Others
DM243 is an EPAC1 activator and STAT3 modulator with an pIC₅₀ of 4.769 for EPAC1. DM243 increases GTP-bound Rap1 levels in EPAC1-expressing cells. DM243 reduces *IL-6/IL-6Rα-evoked STAT3* phosphorylation in endothelial cells. DM243 suppresses TGF-β1-induced fibroblast-to-myofibroblast transition, reducing α-smooth muscle actin and Collagen I levels in lung fibroblasts. DM243 exhibits minimal cytotoxicity in normal human lung fibroblasts .

HY-182274

DM245	Acyltransferase STAT	Others
DM245 is an EPAC1 activator and STAT3 phosphorylation inhibitor with a target pIC₅₀ of 4.801. DM245 activates EPAC1 to increase Rap1-GTP levels, with no activation of EPAC2 or PKA. DM245 reduces IL-6/IL-6Rα-evoked STAT3 phosphorylation in endothelial cells. DM245 suppresses TGF-β1-induced fibroblast-to-myofibroblast transition, reducing αSMA and Collagen I levels. DM245 exhibits minimal cytotoxicity in normal human lung fibroblasts, with negligible loss of intact nuclei after 72 h exposure .

Cat. No.	Product Name	Target	Research Area

HY-P10284

S7	Interleukin Related	Cancer
S7 is an IL-6 receptor antagonist and inhibits the binding between IL-6 and IL-6R. S7 can inhibit angiogenesis and tumor growth .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9917

Tocilizumab 40+ Cited Publications Anti-Human IL6R, Humanized Antibody; RG-1569; rhPM-1	Interleukin Related	Inflammation/Immunology Cancer
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .

HY-P990211

*Anti-Mouse IL-6R* Antibody (15A7)**	Interleukin Related	Inflammation/Immunology Cancer
Anti-Mouse IL-6R Antibody (15A7) is a rat-derived anti-mouse *IL-6R* IgG2b κ type antibody inhibitor. Anti-Mouse IL-6R Antibody (15A7) blocks IL-6 binding to IL-6Rα and inhibits both IL-6 classic and trans-signaling. Anti-Mouse IL-6R Antibody (15A7) can be used for the researches of cancer and inflammation, such as triple-negative breast cancer .

HY-P99112

Satralizumab RG-6168; SA-237	Interleukin Related	Inflammation/Immunology Cancer
Satralizumab is a humanized monoclonal antibody that targets *IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus*. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research .

HY-P9916

Sarilumab Anti-Human IL6Rα, Human Antibody	Interleukin Related STAT Apoptosis	Inflammation/Immunology Cancer
Sarilumab is a monoclonal antibody targeting *IL6* that binds to *IL6R* and blocks the binding of *IL6, thereby inhibiting the activation of the downstream STAT3* phosphorylation signaling pathway. In tumor cells with active *IL6/STAT3* signaling pathways, Sarilumab induces Apoptosis and inhibits cell growth. Sarilumab is applicable to research related to prostate cancer, lung cancer and rheumatoid arthritis .

HY-P99385

Vobarilizumab ALX-0061	Interleukin Related	Inflammation/Immunology
Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (K_d: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .

HY-P99702

Levilimab BCD-089	Interleukin Related	Inflammation/Immunology
Levilimab (BCD-089) is a fully humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody. Levilimab is an inflammation-alleviating antibody. Levilimab can be used for the research of rheumatoid .

HY-P991602

NI-1201 TZLS-501	Interleukin Related	Cancer
NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both *IL-6* cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R .

HY-P991519

VDJ001	Interleukin Related	Inflammation/Immunology
VDJ001 is a high-affinity humanized anti-IL-6R monoclonal antibody. VDJ001 can be used for the study of rheumatoid arthritis .

Recombinant Proteins Recommended:

IL-6R

Species:	Human (8) Rhesus Macaque (1) Rat (4) Mouse (5) Canine (1)
Tag:	His (12) Tag Free (2) Avi (4) Fc (6)
Source:	HEK293 (17) CHO (1) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78472

	IL-6R alpha Protein, Human (HEK293, His-Avi) IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; IL6R; CD126; IL6RQ; gp80	Human	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-P365) is soluble form and expressed by HEK293 cells with a C-Terminal Avi-tag and a C-Terminal His-tag.

HY-P78852

	IL-6R alpha Protein, Mouse (Biotinylated, HEK293, His-Avi) IL6R; CD126; IL-6R-1; IL-6RA; IL6RA; IL-6R-alpha; IL6RQ; gp80	Mouse	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha, Mouse consists of 460 amino acids (M1-R460) with two fibronectin type-III-like domains contained in the N-terminal part (109-214 a.a, 215-313 a.a). Soluble IL-6R (sIL-6R) can be detected in the cerebrospinal fluid, conducts trans signaling by binding IL-6 and dimerized gp130, and exhibits a immune tissue expression property. IL-6R alpha, Mouse (L20-E357) is soluble form and produced in HEK293 cells with a C-Terminal His- and Avi-tag.

HY-P7223

	IL-6R alpha Protein, Human (CHO) 2 Publications Verification rHuIL-6R; IL-6RA; IL-6R 1; CD126; Membrane glycoprotein 80	Human	CHO
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-P365) is soluble form and expressed by CHO cells with a full length of the sequence of 346 amino acids.

HY-P70515

	IL-6R alpha Protein, Human (HEK293, His) Interleukin-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6R 1; Membrane glycoprotein 80; gp80; CD126	Human	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems.IL-6R alpha Protein, Human (HEK293, His) is soluble form and produced in HEK293 cells with a C-Terminal His-tag.

HY-P72388

	IL-6R alpha Protein, Human (Biotinylated, HEK293, Avi-His) Interleukin-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6R 1; Membrane glycoprotein 80; gp80; CD126	Human	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-P365) is soluble and biotinylated recombinant protein expressed by HEK293 cells with a C-Terminal Avi-tag and a C-Terminal His-tag.

HY-P705048

	IL-6R alpha Protein, Human (Biotinylated, HEK293, Fc-Avi) Interleukin-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6R 1; Membrane glycoprotein 80; gp80; CD126	Human	HEK293

HY-P73221

	IL-6R Protein, Canine (HEK293, His) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; gp80; CD126	Canine	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha, Canine consists of 462 amino acids (M1-R462) and is produced in HEK293 cells with a C-Terminal His-tag.

HY-P73224

	IL-6R Protein, Rat (HEK293, His) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; gp80; CD126	Rat	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha, Rat consists of 462 amino acids (M1-R462) with a fibronectin type-III-like domain contained in the N-terminal part (215-313 a.a) and a transmembrane domain (365-385 a.a). Soluble IL-6R (sIL-6R) interacts with SORL1 to conduct internalization and binds IL-6 and dimerized gp130 to deliver trans signalin. IL-6R alpha, Rat (I44-E357) is soluble form and produced in HEK293 cells with a C-Terminal His-tag.

HY-P73876

	IL-6R Protein, Rat (HEK293, Fc) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; gp80; CD126	Rat	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. with a fibronectin type-III-like domain contained in the N-terminal part and a transmembrane domain. Soluble IL-6R (sIL-6R) interacts with SORL1 to conduct internalization and binds IL-6 and dimerized gp130 to deliver trans signalin. IL-6R alpha, Rat is soluble form and produced in HEK293 cells with a C-Terminal hFc-tag.

HY-P73222

	IL-6R alpha Protein, Human (HEK293, Fc) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; gp80; CD126	Human	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (M1-P365) is soluble form and produced in HEK293 cells with a C-Terminal hFc-tag.

HY-P73225

	IL-6R Protein, Rhesus Macaque (HEK293, His) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; gp80; CD126	Rhesus Macaque	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha, Rhesus Macaque consists of 365 amino acids (M1-P365) and is produced in HEK293 cells with a C-Terminal His-tag.

HY-P72538

	IL-6R alpha Protein, Mouse (HEK293, His) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; sIL6R; CD126	Mouse	HEK293
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha, Mouse consists of 460 amino acids (M1-R460) with two fibronectin type-III-like domains contained in the N-terminal part (109-214 a.a, 215-313 a.a). Soluble IL-6R (sIL-6R) can be detected in the cerebrospinal fluid, conducts trans signaling by binding IL-6 and dimerized gp130, and exhibits a immune tissue expression property. IL-6R alpha Protein, Mouse (HEK293, His) is soluble form and produced in HEK293 cells with a C-Terminal His-tag.

HY-P704718

	IL-6R alpha Protein, Mouse (HEK293, Fc) Interleukin-6 receptor subunit alpha; IL-6R-alpha; IL-6R 1; sIL6R; CD126	Mouse	HEK293

HY-P7377

	IL-6R alpha Protein, Human (sf9) rHuIL-6 Receptor α; gp80; CD126	Human	Sf9 insect cells
	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-D358) is soluble form and expressed by sf9 insect cells

HY-P705639

	*IL-6/IL-6R* alpha Protein, Human (HEK293, His)** Interleukin-6 receptor subunit alpha; L-6R subunit alpha; IL-6R-alpha; IL-6R 1; Membrane glycoprotein 80; gp80; CD126; IL-6/IL-6R alpha Chimera Protein	Human	HEK293

HY-P76370

	gp130/IL6ST Protein, Mouse (HEK293, Fc) Interleukin-6 receptor subunit beta; IL-6R-beta; IL-6RB; gp130; CD130	Mouse	HEK293
	Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Mouse (HEK293, Fc) is a recombinant protein with a Fc labe.

HY-P76371

	gp130/IL6ST Protein, Mouse (HEK293, His) Interleukin-6 receptor subunit beta; IL-6R-beta; IL-6RB; gp130; CD130	Mouse	HEK293
	Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Mouse (617a.a, HEK293, His) is a recombinant protein with a His label and is produced by HEK293 cells.

HY-P76374

	gp130/IL6ST Protein, Rat (HEK293, His) Interleukin-6 receptor subunit beta; IL-6R-beta; IL-6RB; gp130; CD130	Rat	HEK293
	Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rat (HEK293, His) is a recombinant protein with a His label that consists of 614 amino acids (M4-E618) and is produced by HEK293 cells.

HY-P76375

	gp130/IL6ST Protein, Rat (HEK293, His-Fc) Interleukin-6 receptor subunit beta; IL-6R-beta; IL-6RB; gp130; CD130	Rat	HEK293
	Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. gp130/IL6ST Protein, Rat (HEK293, His-Fc) is produced by HEK293 cells.

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Species
Source
Tag
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Storage & Stability
Shipping
Free Sample	Yes No
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Host:	Mouse (2)
Reactivity:	Human (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (2) WB (2) FC (2) ELISA (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2) Biotin (3)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81629

	IL-6R Antibody CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse
	IL-6R Antibody is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-6R.

HY-P81629A

	IL-6R Antibody(PBS only) CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse
	IL-6R Antibody is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-6R.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS06777

IL6R Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
IL6R Human Pre-designed siRNA Set A contains three designed siRNAs for IL6R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23587

Il6r Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Il6r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il6r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174599

*Human IL6R* mRNA**		mRNA Interleukin & Receptors
Human IL6R mRNA encodes the human interleukin 6 receptor (IL6R) protein, a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response.

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Oligonucleotides