1. Immunology/Inflammation
  2. Interleukin Related
  3. Satralizumab

Satralizumab 

Cat. No.: HY-P99112

Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.

For research use only. We do not sell to patients.

Satralizumab Chemical Structure

Satralizumab Chemical Structure

CAS No. : 1535963-91-7

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Description

Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].

IC50 & Target

IL-6

 

In Vivo

Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rattus norvegicus (forty, male, 10-week-old, four equal groups)[1]
Dosage: 120 mg
Administration: Subcutaneously, once every 2 weeks, for 4 weeks
Result: Prevented dTAA (descending thoracic aorta aneurysm) formation and progression.
CAS No.
SMILES

[Satralizumab]

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Satralizumab
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