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Satralizumab

(Synonyms: RG-6168; SA-237)
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Based on 1 Customer Validation

Satralizumab is a humanized monoclonal antibody that targets IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.

For research use only. We do not sell to patients.

  • Purity: 99.82%
  • CAS No.: 1535963-91-7
  • Molecular Weight:144.5 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Satralizumab Chemical Structure
    Satralizumab Chemical Structure
CAS No.: 1535963-91-7
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Satralizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Satralizumab Chemical Structure
    1/16
  • Satralizumab
  • Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.
  • Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).