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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
IRAP
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "IRAP" in MCE Product Catalog:
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1 Cited Publications
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HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2.01 μM .
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Aminopeptidase-IN-1 is an insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used for the research of memory impairments .
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Aminopeptidase N (rat) (APN/CD13) is a Zn 2+-dependent membrane-bound exopeptidase that preferentially degrades proteins and peptides with N-terminal neutral amino acids. Aminopeptidase N (rat) is inhibited by angiotensin IV and participates in the regulation of angiotensin IV half-life in the rat striatum .
Cat. No.: HY-160239
CAS No.: 1110650-74-2
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HFI-437 is a potent non-peptidic insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 20 nM. HFI-437 is a cognitive enhancer .
Cat. No.: HY-163714
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IRAP-IN-1 (compound 3) is a potent and selective insulin regulated aminopeptidase (IRAP) inhibitor with an IC50 value of 157 nM .
Cat. No.: HY-168181
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ERAP1-IN-2 (compound 3f) is an inhibitor of ERAP1 (endoplasmic reticulum aminopeptidase 1). ERAP1-IN-2 has an IC50 value of 1.72 μM against hERAP1 .
Cat. No.: HY-173022
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BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC50 of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively .
Cat. No.: HY-RS07730
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LNPEP Human Pre-designed siRNA Set A contains three designed siRNAs for LNPEP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06727
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IL1RN Human Pre-designed siRNA Set A contains three designed siRNAs for IL1RN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P700197AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Il1rn; Il-1raInterleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; IL1 inhibitor
Cat. No.: HY-P11643
CAS No.: 75808-66-1
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Cat. No.: HY-P700110AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICIL-1RA; IRAP; IL-1RN
Cat. No.: HY-179625
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GSK235 is an orally active, selective and allosteric endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor with pIC50 values of 8.45 and 7.59 for human and mouse ERAP1, respectively. GSK235 exhibits over 1000-fold selectivity for the two most homologous enzymes, ERAP2 and IRAP. GSK235 can regulate the immunopeptidome of cancer cells and enhance cancer cell antigenicity. GSK235 can be used for the study of colorectal cancer and arthritis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
