Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Integrin β2
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Integrin β2" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 μM) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury [2].
Target:
Cat. No.: HY-175288
Research Areas:
αMβ2 integrin agonist-1 (Compound 8) is a highly selective αMβ2 integrin agonist with anti-inflammatory activity (EC50=1.4 nM). αMβ2 integrin agonist-1 activates integrin-mediated cell adhesion and JNK/ERK signaling. αMβ2 integrin agonist-1 induces tumor-associated macrophage repolarization and enhances antitumor T-cell immune responses. αMβ2 integrin agonist-1 is promising for research of cancers and chronic inflammatory diseases (e.g., pancreatic cancer, rheumatoid arthritis) .
Cat. No.: HY-175286
Research Areas:
α4β1 antagonist-1 (Compound 4) is a highly selective α4β1 integrin antagonist (IC50=15 nM). α4β1 antagonist-1 inhibits integrin-mediated cell adhesion and ERK1/2 signaling activation. α4β1 antagonist-1 also exhibits partial agonism toward αMβ2 integrin (EC50=23 nM). α4β1 antagonist-1 is promising for research of chronic inflammatory diseases (e.g., rheumatoid arthritis, multiple sclerosis) and cancers .
Cat. No.: HY-177318
CAS No.: 579526-88-8
Target:
Research Areas:
αLβ2 integrin-IN-1 (example 1) is an αLβ2 integrin mediated cell adhesion inhibitor that can be used for the study of αLβ2 integrin mediated inflammatory conditions .
Cat. No.: HY-123277
CAS No.: 307525-40-2
Target:
Research Areas:
IMB-10 is an αMβ2 integrin ligand. IMB-10 inhibits αMβ2-dependent migration and inflammation-induced neutrophil emigration .
Cat. No.: HY-P991604
Synonyms: YFC51.1; LDP-01
Target:
Research Areas:
Cat. No.: HY-139137
CAS No.: 139332-94-8
Synonyms: AGGC
Target:
Research Areas:
N-Acetyl-S-geranylgeranyl-L-cysteine is a Methyltransferase inhibitor. N-Acetyl-S-geranylgeranyl-L-cysteine inhibits beta 2 integrin-induced actin polymerization with an IC50 of 45 nM .
Cat. No.: HY-P991825
Target:
Research Areas:
Cat. No.: HY-P704217
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Integrin alpha L beta 2; LITGAL&ITGB2
Cat. No.: HY-P705545
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Cat. No.: HY-P700758
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: αLβ2; ITGAL&ITGB2; ITGAL; ITGB2
Cat. No.: HY-P700759
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: αMβ2; ITGAM&ITGB2; ITGAM; ITGB2; Mac-1; complement receptor-3 (CR3)
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
