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Cat. No.: HY-123277

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IMB-10

IMB-10 is an α_Mβ₂ integrin ligand. IMB-10 inhibits α_Mβ₂-dependent migration and inflammation-induced neutrophil emigration.

For research use only. We do not sell to patients.

CAS No.: 307525-40-2
Formula: C₁₉H₁₅NOS₂
Molecular Weight:337.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

IMB-10 Chemical Structure

CAS No.: 307525-40-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

IMB-10 is an α_Mβ₂ integrin ligand. IMB-10 inhibits α_Mβ₂-dependent migration and inflammation-induced neutrophil emigration^[1].

All Integrin Isoforms :

Chemical Information

CAS No. 307525-40-2
Molecular Weight 337.46
Formula C₁₉H₁₅NOS₂
SMILES

O=C1N(C(S/C1=C\C=C\C2=CC=CC=C2)=S)C3=CC=CC=C3C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Björklund M, et al. Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment. Biochemistry. 2006 Mar 7;45(9):2862-71. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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IMB-10

All Integrin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

IMB-10 Related Classifications

HY-123277 Related Classifications