21 Results for "

L-Selectin

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "L-Selectin" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-106139
CAS No.: 187269-40-5
Purity:  98.82%
Synonyms: TBC-1269
Research Areas:  

Inflammation/Immunology

Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects .
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1
1 Cited Publications
Cat. No.: HY-108610A
CAS No.: 70641-51-9
Purity:  ≥99.0%
Synonyms: ET-18-OCH3
Edelfosine (ET-18-OCH3) is an orally active lipid raft modulator and apoptosis inducer that alters membrane fluidity and preferentially inserts into tumor cell membranes. Edelfosine recruits death receptor ligands (FasL/CD95L, TRAIL) and Bid to lipid rafts to form death-inducing signaling complexes, thereby initiating mitochondria-dependent apoptosis and inducing cytochrome c release. Edelfosine also exerts anti-inflammatory effects, promotes L-Selectin shedding, and causes no gastrointestinal or organ toxicity. In addition, Edelfosine inhibits nucleic acid and protein synthesis in Leishmania donovani and exhibits antiproliferative activity. Edelfosine can be used in research on multiple myeloma, inflammatory bowel diseases (such as ulcerative colitis and Crohn's disease), and visceral leishmaniasis .
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1
1 Cited Publications
Cat. No.: HY-W020790
CAS No.: 98603-84-0
Synonyms: sLeX
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .
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1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule (Indian blood group) antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody; HCELL antibody; hematopoietic cell E- and L-Selectin ligand antibody; Heparan sulfate proteoglycan antibody; Hermes antigen antibody; homing function and Indian blood group system antibody; HSA antibody; HUTCH-I antibody; HUTCH1 antibody; Hyaluronate receptor antibody; IN antibody; MC56 antibody; MDU2 antibody; MDU3 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-136888
CAS No.: 65144-34-5
Purity:  99.73%
Synonyms: Elastase Inhibitor III
MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor that simultaneously inhibits Cathepsin G and Proteinase 3. MeOSuc-AAPV-CMK blocks the shedding of FcgRIIIb on the surface of human neutrophils. MeOSuc-AAPV-CMK reverses the elastase-mediated reduction in proinflammatory cytokine production by immune cells, partially restores IL-1β levels in immune cell co-culture systems, and prevents elastase-mediated adiponectin cleavage .
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Cat. No.: HY-P99443
CAS No.: 395639-53-9
Synonyms: HuDreg-55

Target:  

P-selectin

Research Areas:  

Inflammation/Immunology

Aselizumab (HuDreg-55) is an humanized IgG4 mAb against L-selectin. However, L-selectin (CD62L) is a cell adhesion molecule expressed on circulating neutrophils. It regulates migrating cells to chemotaxis towards the site of injury. Aselizumab may be account for a high rate of infections and leucopenia after truma .
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Cat. No.: HY-P990201
Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) is an anti-mouse L-Selectin/CD62L IgG2a monoclonal antibody. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can significantly inhibit the migration of T cells and B cells. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can block initial lymphocyte homing. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can be used for researches on inflammation, metabolic and infection conditions such as diabetes and parasitic infections .
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Cat. No.: HY-106139A
CAS No.: 187269-60-9
Synonyms: TBC-1269Z
Target:  

P-selectin

Research Areas:  

Inflammation/Immunology

Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects .
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Cat. No.: HY-P991794

Target:  

L-Selectin

Research Areas:  

Inflammation/Immunology Cancer

Anti-Rat L-selectin Antibody (OX-85) reacts with rat L-selectin (CD62L). Anti-Rat L-selectin Antibody (OX-85) inhibits L-selectin in vivo and in vitro. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-106139R
CAS No.: 187269-40-5
Synonyms: TBC-1269 (Standard)
Research Areas:  

Inflammation/Immunology

Bimosiamose (Standard) is the analytical standard of Bimosiamose. This product is intended for research and analytical applications. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects .
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Cat. No.: HY-P74767
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: L-Selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1
Species:  
Source:  
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Cat. No.: HY-P74766
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: L-Selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1
Species:  
Source:  
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Cat. No.: HY-P74768
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: L-Selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1
Species:  
Source:  
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Cat. No.: HY-P77483
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: L-Selectin; Sell; CD62 antigen-like family member L; LECAM1; CD62L; LAM-1
Species:  
Source:  
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Cat. No.: HY-P70312
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuL-Selectin, His; L-Selectin; Sell; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; CD62L
Species:  
Source:  
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Cat. No.: HY-P76638
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: L-Selectin; LAM-1; LECAM1; TQ1; gp90-MEL; CD62L; SELL; LNHR; LYAM1
Species:  
Rat
Source:  
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Cat. No.: HY-P85001
Synonyms: TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1; L-Selectin; LECAM-1; SELL; LAM-1; TQ-1; MEL-14; CD62L nanobody;

Host:  

Mouse

Application:  

ELISA, FC

Reactivity:  

Human

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Cat. No.: HY-RS24218
Research Areas:  

Others

Sell Rat Pre-designed siRNA Set A contains three designed siRNAs for Sell gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992212

Target:  

L-Selectin

Research Areas:  

Inflammation/Immunology

Anti-CD62L Antibody (DREG-200) is a human monoclonal antibody targeting CD62L/L-selectin. Anti-CD62L Antibody (DREG-200) binds to residues 45, 46 and 47 of L-selectin, and blocks L-selectin-mediated interactions, neutrophil rolling, adhesion, aggregation, secondary anchoring, as well as leukocyte rolling on ligands. Anti-CD62L Antibody (DREG-200) reduces myocardial necrosis, coronary endothelial dysfunction, and neutrophil migration driven by neutrophil microparticles. Anti-CD62L Antibody (DREG-200) exerts cardioprotective effects in feline models. Anti-CD62L Antibody (DREG-200) can be used in studies related to myocardial ischemia-reperfusion injury. The recommended isotype control is Mouse IgG1 kappa (HY-P99977) .
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Cat. No.: HY-P811085
Synonyms: CD62L, Lnhr, Ly-22, Ly22, Sell, L-Selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, Lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen, LAM-1, LECAM1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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