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Lotus

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (1) Autophagy (1) Bacterial (1) Beclin1 (1) Biochemical Assay Reagents (1) Drug Derivative (1) EGFR (1) Endogenous Metabolite (1) ERK (1) Fluorescent Dye (1) Glycosidase (1) HSP (1) NO Synthase (1) Potassium Channel (1) Small Interfering RNA (siRNA) (2) Tyrosinase (1)
By Research Areas:	Cancer (2) Infection (2) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-133685

N-Hexanoyl-L-homoserine lactone C6-HSL	Bacterial	Infection Metabolic Disease
N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis .

HY-N1073

Wighteone 1 Publications Verification 6-Isopentenylgenistein; Erythrinin B	Apoptosis EGFR HSP ERK Akt	Infection Cancer
Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR ^L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR ^L858R/T790M mutation, and fungal infections .

HY-NP070

Lotus tetragonolobus lectin LTL		Inflammation/Immunology
Lotus tetragonolobus lectin (LTL) is a plant lectin that specifically recognizes and binds to α-L-fucopyranosyl residues, a sugar structure serving as the key terminal glycosyl group of human blood type O antigen (H antigen). Lotus tetragonolobus lectin exerts macrophage migration inhibitory activity in monomeric form. Lotus tetragonolobus lectin labels and identifies renal proximal tubular epithelial cells to evaluate histopathological changes of sepsis-induced acute kidney injury. Lotus tetragonolobus lectin is applicable to studies in glycobiology, immunology and renal pathology .

HY-NP0135

Lotus Tetragonolobus Lectin (Fluorescein) LTL (Fluorescein)	Fluorescent Dye	Others
Lotus Tetragonolobus Lectin (LTL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lotus Tetragonolobus Lectin (LTL) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-N7511

O-Nornuciferine	Potassium Channel Endogenous Metabolite	Metabolic Disease
O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor .

HY-156261

Beef extract	Biochemical Assay Reagents	Others
Beef extract is a common ingredient in the preparation of biological culture media .

HY-N8742

Geraldol	Others	Others
Geraldol is a Flavonoids product that can be isolated from the herbs of Lotus corniculatus L. .

HY-NP153

Lotus Tetragonolobus Lectin (Biotinylated) LTL (Biotinylated)	Glycosidase	Others
Lotus Tetragonolobus Lectin (LTL) (Biotinylated) is a biotinylated derivative of Lotus Tetragonolobus Lectin (HY-NP070), with both sugar-binding specificity and biotin labeling. Lotus Tetragonolobus Lectin (Biotinylated) is used to detect proteins, glycoproteins and lectins on nitrocellulose membranes .

HY-N3182

N-Methylnuciferine	Others	Neurological Disease
N-Methylnuciferine, an alkaloid from Lotus Plumule, ameliorate lipopolysaccharide-induced depression-like behavior .

HY-N13222

Lotus Leaf Extract	Others	Others
Lotus Leaf Extract is the extract of Lotus Leaf, with content of 2% , 3% Nuciferine HPLC.

HY-N7655

7-O-Methylbiochanin A 4',7-Dimethoxy-5-hydroxyisoflavone	Others	Others
7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos .

HY-N3182A

N-Methylnuciferine iodide	NO Synthase Beclin1 Autophagy	Neurological Disease
N-Methylnuciferine iodide, an alkaloid from Lotus Plumule, ameliorate lipopolysaccharide-induced depression-like behavior .

HY-RS03197

CRTAC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CRTAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for CRTAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CRTAC1 Human Pre-designed siRNA Set A CRTAC1 Human Pre-designed siRNA Set A

HY-158235

Tyrosinase-IN-27	Tyrosinase	Others
Tyrosinase-IN-27 (compound 6f) is a tyrosinase (TYR) inhibitor (IC₅₀: 0.88 μM) that statically quenches TYR. Tyrosinase-IN-27 increases the hydrophobicity of the enzyme microenvironment by binding to TYR, reducing the content of α-helices in the enzyme and changing its secondary structure. Tyrosinase-IN-27 can be used in the food industry to effectively inhibit the browning of lotus root slices. .

HY-RS20542

Crtac1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Crtac1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Crtac1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Crtac1 Mouse Pre-designed siRNA Set A Crtac1 Mouse Pre-designed siRNA Set A

HY-N19047

Saussurea involucrata extract	Others	Others
Saussurea Involucrata Extract is the active ingredient obtained from the Compositae plant snow lotus, and the main active ingredient is rutin. It has a variety of beauty effects.

HY-W647305

4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol	Others	Others
4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol is a Lignans product that can be isolated from the herbs of Diospyros lotus .

HY-N10337

Norjuziphine (-)-Norjuziphine	Drug Derivative	Cancer
Norjuziphine ((-)-Norjuziphine) is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC₅₀=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases .

Cat. No.	Product Name	Type

HY-NP070

Lotus tetragonolobus lectin LTL	Biochemical Assay Reagents
Lotus tetragonolobus lectin (LTL) is a plant lectin that specifically recognizes and binds to α-L-fucopyranosyl residues, a sugar structure serving as the key terminal glycosyl group of human blood type O antigen (H antigen). Lotus tetragonolobus lectin exerts macrophage migration inhibitory activity in monomeric form. Lotus tetragonolobus lectin labels and identifies renal proximal tubular epithelial cells to evaluate histopathological changes of sepsis-induced acute kidney injury. Lotus tetragonolobus lectin is applicable to studies in glycobiology, immunology and renal pathology .

Lotus tetragonolobus lectin

LTL

Biochemical Assay Reagents

Lotus tetragonolobus lectin (LTL) is a plant lectin that specifically recognizes and binds to α-L-fucopyranosyl residues, a sugar structure serving as the key terminal glycosyl group of human blood type O antigen (H antigen). Lotus tetragonolobus lectin exerts macrophage migration inhibitory activity in monomeric form. Lotus tetragonolobus lectin labels and identifies renal proximal tubular epithelial cells to evaluate histopathological changes of sepsis-induced acute kidney injury. Lotus tetragonolobus lectin is applicable to studies in glycobiology, immunology and renal pathology .

HY-NP0135

Lotus Tetragonolobus Lectin (Fluorescein) LTL (Fluorescein)	Biochemical Assay Reagents
Lotus Tetragonolobus Lectin (LTL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lotus Tetragonolobus Lectin (LTL) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-156261

Beef extract	Biochemical Assay Reagents
Beef extract is a common ingredient in the preparation of biological culture media .

HY-NP153

Lotus Tetragonolobus Lectin (Biotinylated) LTL (Biotinylated)	Biochemical Assay Reagents
Lotus Tetragonolobus Lectin (LTL) (Biotinylated) is a biotinylated derivative of Lotus Tetragonolobus Lectin (HY-NP070), with both sugar-binding specificity and biotin labeling. Lotus Tetragonolobus Lectin (Biotinylated) is used to detect proteins, glycoproteins and lectins on nitrocellulose membranes .

Wighteone 1 Publications Verification 6-Isopentenylgenistein; Erythrinin B	Leguminosae Genista ephedroides DC. Plants Isoflavones Source Classification	Apoptosis EGFR HSP ERK Akt
Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR ^L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR ^L858R/T790M mutation, and fungal infections .

O-Nornuciferine	Alkaloids Monophenols other families Classification of Application Fields Phenols Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Potassium Channel Endogenous Metabolite
O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor .

Geraldol	Flavonoids Lotus corniculatus L. Plants Fabaceae Source Classification	Others
Geraldol is a Flavonoids product that can be isolated from the herbs of Lotus corniculatus L. .

N-Methylnuciferine	Alkaloids other families Quinoline Alkaloids Plants Source Classification	Others
N-Methylnuciferine, an alkaloid from Lotus Plumule, ameliorate lipopolysaccharide-induced depression-like behavior .

7-O-Methylbiochanin A 4',7-Dimethoxy-5-hydroxyisoflavone	Flavonoids Monophenols Classification of Application Fields Other Diseases Phenols Nelumbo nucifera Gaertn. Plants Disease Research Fields Nymphaeaceae Isoflavones Source Classification	Others
7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos .

Saussurea involucrata extract	Structural Classification Extract	Others
Saussurea Involucrata Extract is the active ingredient obtained from the Compositae plant snow lotus, and the main active ingredient is rutin. It has a variety of beauty effects.

4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol	Ebenaceae Lignans Phenylpropanoids Plants Diospyros lotus L. Source Classification	Others
4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol is a Lignans product that can be isolated from the herbs of Diospyros lotus .

Norjuziphine (-)-Norjuziphine	Alkaloids Nelumbo nucifera Gaertn. Quinoline Alkaloids Plants Nymphaeaceae Source Classification	Drug Derivative
Norjuziphine ((-)-Norjuziphine) is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC₅₀=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases .

CRTAC1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CRTAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for CRTAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Crtac1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Crtac1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Crtac1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Lotus

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Biochemical Assay Reagents

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