46 Results for "

Natural product derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "Natural product derivatives" in MCE Product Catalog:

Cat. No.: HY-78004S
CAS No.: 94371-89-8
1,2-Diphenylethane-d14 is the d14-labeled Bibenzyl (HY-78004). Bibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities .
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Cat. No.: HY-112624H
CAS No.: 9004-54-0
Synonyms: Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
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Cat. No.: HY-112624E
CAS No.: 9004-54-0
Synonyms: Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Cat. No.: HY-N10902
CAS No.: 5594-30-9
Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives. Methyl pheophorbide a is a photosensitizer that produces singlet oxygen and reactive oxygen species (ROS) under light of specific wavelength, thereby leading to cell death .
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Cat. No.: HY-W010542S
CAS No.: 169297-53-4
Research Areas:  

Infection

Azepan-2-one-d10 is the deuterated-labeled Azepan-2-one (HY-W010542). Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research .
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Cat. No.: HY-N8344
CAS No.: 521-62-0
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .
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Cat. No.: HY-W094994
CAS No.: 244-76-8
Synonyms: alpha-Carboline
Target:  

Drug Intermediate

Research Areas:  

Others

α-carboline (alpha-Carboline) is a promising scaffold compound for medicinal chemistry. α-carboline natural products and their derivatives possess diverse bioactivities .
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Cat. No.: HY-W142618
CAS No.: 13265-84-4
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
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Cat. No.: HY-N4012
CAS No.: 5548-10-7
Synonyms: 3-Indoleglyoxamide
Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .
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Cat. No.: HY-W039102
CAS No.: 1569103-64-5
Research Areas:  

Cancer

N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .
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Cat. No.: HY-78004
CAS No.: 103-29-7
Synonyms: s-Diphenylethane; Dibenzyl
Bibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities .
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Cat. No.: HY-Y0519R
CAS No.: 289-95-2
Pyrimidine (Standard) is the analytical standard of Pyrimidine (HY-Y0519). This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound that serves as a scaffold for numerous natural and synthetic derivatives. As a pharmacophore, pyrimidine interacts with the synthesis and function of nucleic acids. Pyrimidine derivatives are used in research related to pancreatic cancer, triple-negative breast cancer, colon cancer, and leukemia .
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Cat. No.: HY-N0139R
CAS No.: 7085-55-4
Synonyms: Trihydroxyethylrutin (Standard)
Troxerutin (Standard) is the analytical standard of Troxerutin. This product is intended for research and analytical applications. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
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Cat. No.: HY-N1181R
CAS No.: 603-61-2
Synonyms: 4'-O-Methyl Quercetin (Standard)
Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
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Cat. No.: HY-W010542
CAS No.: 105-60-2
Target:  

Drug Intermediate

Research Areas:  

Infection

Azepan-2-one is a seven-membered lactam (cyclic amide) scaffold found in the natural product Capuramycin. It serves as the core structural component required for the CB2 agonist activity of 4-(1,2,4-oxadiazol-5-yl) azepan-2-one derivatives. Azepan-2-one is used in tuberculosis research .
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Cat. No.: HY-W587784
CAS No.: 542-40-5
Norbixin is an orally active natural product with multiple activities such as retinal protection and oxidative stress regulation. Norbixin scavenges ROS, chelates metal ions, regulates plasmid and genomic DNA breakage, inhibits H2O2-induced mutagenesis, activates PPAR-α, modulates lipid levels, restores or regulates antioxidant enzyme activity, and alters NO levels. Norbixin prevents A2E accumulation and protects photoreceptor cells and retinal pigment epithelial cells. Norbixin is a derivative of Bixin (HY-N6884). Norbixin can be used in research related to diseases such as macular degeneration and diabetes, and also serves as a natural textile dye .
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Cat. No.: HY-N2099A
CAS No.: 162681-53-0
Synonyms: (Z)-Senegin III
(Z)-Onjisaponin B ((Z)-Senegin III) is a derivative of Onjisaponin B (HY-N2099). Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB .
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Cat. No.: HY-N3553
CAS No.: 103630-03-1
Catechin 3-O-α-L-rhamnopyranoside is a natural product that can be isolated from the twigs of Artocarpus lakoocha .
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Cat. No.: HY-W065053
CAS No.: 131559-49-4
trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative .
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Cat. No.: HY-15459R
CAS No.: 183133-96-2
Synonyms: XRP6258 (Standard); RPR-116258A (Standard); taxoid XRP6258 (Standard)
Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
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