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Results for "

Natural product derivatives

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (3) ADC Payload (1) Akt (1) Apoptosis (2) ATM/ATR (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (4) Caspase (1) CDK (1) ClpP (1) COX (1) Drug Derivative (3) Drug Intermediate (3) Endogenous Metabolite (2) Hedgehog (1) Interleukin Related (1) JNK (1) Microtubule/Tubulin (1) NF-κB (1) NOD-like Receptor (NLR) (1) p38 MAPK (1) Photosensitizer (1) Reactive Oxygen Species (ROS) (2) Reference Standards (9) Sodium Channel (1) STAT (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (4)

By Targets:

Amino Acid Derivatives (3)

ADC Payload (1)

Akt (1)

Apoptosis (2)

ATM/ATR (1)

Autophagy (1)

Bacterial (1)

Biochemical Assay Reagents (4)

Caspase (1)

CDK (1)

ClpP (1)

COX (1)

Drug Derivative (3)

Drug Intermediate (3)

Endogenous Metabolite (2)

Hedgehog (1)

Interleukin Related (1)

JNK (1)

Microtubule/Tubulin (1)

NF-κB (1)

NOD-like Receptor (NLR) (1)

p38 MAPK (1)

Photosensitizer (1)

Reactive Oxygen Species (ROS) (2)

Reference Standards (9)

Sodium Channel (1)

STAT (1)

By Research Areas:

Cancer (8)

Cardiovascular Disease (2)

Infection (1)

Inflammation/Immunology (6)

Metabolic Disease (3)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Targets Recommended: Amino Acid Derivatives

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-112624H

Dextran T2 (MW 2,000) Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)	Biochemical Assay Reagents	Others
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-112624E

Dextran T0.8 (MW 800) Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)	Biochemical Assay Reagents	Others
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-N10902

Methyl pheophorbide a	Photosensitizer Reactive Oxygen Species (ROS) Caspase Apoptosis	Cancer
Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives. Methyl pheophorbide a is a photosensitizer that produces singlet oxygen and reactive oxygen species (ROS) under light of specific wavelength, thereby leading to cell death .

HY-N8344

Frangulin A	Others	Others
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .

HY-W035904

Tropone Cycloheptatrienone	Drug Intermediate	Others
Tropone (Cycloheptatrienone) is a non-benzene aromatic natural product and a derivative of a tropane-type compound. Tropone is the direct precursor of various tropane-type natural products, such as Tropolone (HY-N7135) and Tropodithietic acid (HY-N6705), and can be used as a drug intermediate in their biosynthesis .

HY-W094994

α-Carboline alpha-Carboline	Drug Intermediate	Others
α-carboline (alpha-Carboline) is a promising scaffold compound for medicinal chemistry. α-carboline natural products and their derivatives possess diverse bioactivities .

HY-W142618

D-Glucal	Biochemical Assay Reagents	Others
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-N4012

Indole-3-glyoxylamide 3-Indoleglyoxamide	Others	Others
Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine	Amino Acid Derivatives	Cancer
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .

HY-N0139R

Troxerutin (Standard) Trihydroxyethylrutin (Standard)	Reference Standards NOD-like Receptor (NLR)	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Troxerutin (Standard) is the analytical standard of Troxerutin. This product is intended for research and analytical applications. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.

HY-N1181R

Tamarixetin (Standard) 4'-O-Methyl Quercetin (Standard)	Reference Standards Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species (ROS)	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC₅₀ of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .

HY-N2099A

(Z)-Onjisaponin B (Z)-Senegin III	Drug Derivative	Neurological Disease Metabolic Disease Inflammation/Immunology
(Z)-Onjisaponin B ((Z)-Senegin III) is a derivative of Onjisaponin B (HY-N2099). Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB .

HY-N3553

Catechin 3-O-α-L-rhamnopyranoside	Others	Others
Catechin 3-O-α-L-rhamnopyranoside is a natural product that can be isolated from the twigs of Artocarpus lakoocha .

HY-N12418

(20S)-18,19-Dehydrocamptothecin	Others	Cancer
(20S)-18,19-Dehydrocamptothecin is a natural product that can be isolated from Nothapodytes Foetida .

HY-W065053

trans-N-Methyl-4-methoxyproline	Amino Acid Derivatives	Others
trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative .

HY-135170R

Myristoyl-L-carnitine chloride (Standard)	Amino Acid Derivatives Reference Standards	Others
Myristoyl-L-carnitine chloride (Standard) is the analytical standard of Myristoyl-L-carnitine chloride (HY-135170). This product is intended for research and analytical applications. Myristoyl-L-Carnitine Chloride is a natural long-chain glycoline, amino acid derivative.

HY-15459R

Cabazitaxel (Standard) XRP6258 (Standard); RPR-116258A (Standard); taxoid XRP6258 (Standard)	Reference Standards Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-N7650

Dihydroseselin	Biochemical Assay Reagents	Others
Dihydroseselin is a derivative of 7-hydroxycoumarin (HY-N0573). 7-hydroxycoumarin, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent

HY-A0126AR

Epoprostenol sodium (Standard) Prostaglandin I2 sodium salt (Standard); Prostacyclin sodium salt (Standard); Flolan (Standard)	Reference Standards Endogenous Metabolite	Cardiovascular Disease
Epoprostenol (sodium) (Standard) is the analytical standard of Epoprostenol (sodium). This product is intended for research and analytical applications. Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH) . Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation .

HY-N0446R

10-Methoxycamptothecin (Standard)	ADC Payload Reference Standards	Cancer
10-Methoxycamptothecin (Standard) is the analytical standard of 10-Methoxycamptothecin. This product is intended for research and analytical applications. 10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines .

HY-N6954R

Garcinone C (Standard)	Reference Standards ATM/ATR STAT CDK Hedgehog	Inflammation/Immunology Cancer
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .

HY-N1295

Serratenediol diacetate	Others	Others
Serratenediol diacetate is a serratane-type triterpenoid compound, mainly used as a derivative of natural triterpenoids in natural product chemistry research and potential bioactivity screening. Serratenediol diacetate can be prepared from serratenediol isolated from Lycopodium complanatum L. (a plant of the Lycopodiaceae family, genus Lycopodium) .

HY-N17531

4-(β-D-Glucopyranosyloxy)benzenepropanoic acid	Drug Derivative	Others
4-(β-D-Glucopyranosyloxy) benzenepropanoic acid is a phenolic acid glycoside natural product, which has an O-β-D-glucoside structure formed by a phenylpropanoic acid derivative and glucose .

HY-W035904R

Tropone (Standard) Cycloheptatrienone (Standard)	Drug Intermediate Reference Standards	Others
Tropone (Standard) is the analytical standard of Tropone (HY-W035904). This product is intended for research and analytical applications. Tropone (Cycloheptatrienone) is a non-benzene aromatic natural product and a derivative of a tropane-type compound. Tropone is the direct precursor of various tropane-type natural products, such as Tropolone (HY-N7135) and Tropodithietic acid (HY-N6705), and can be used as a drug intermediate in their biosynthesis .

HY-N9836

8,9-Dehydrothymol isobutyrate	Drug Derivative	Others
8,9-Dehydrothymol isobutyrate is a thymol (HY-N6810) derivative that can be naturally extracted from the essential oil of the trunk bark of Tetraclinis articulata (Vahl) Mast. This plant essential oil exhibits certain cytotoxicity and can be used as a research subject in the fields of natural product chemistry and the active components of plant essential oils .

HY-N20631

Dihydro-α-norcurcumenic acid	Others	Others
Dihydro-α-norcurcumenic acid, a sesquiterpenoid, is a hydrogenated derivative of α-santalic acid and terpenoic acid that can be found in East Indian sandalwood. Terpenoids are the most abundant and structurally diverse class of natural products found in many plants. In vitro, preclinical, and clinical studies have demonstrated that terpenoids exhibit broad and significant pharmacological properties in the treatment of cancer, malaria, inflammation, and various infectious diseases .

HY-179445

Nav1.7-IN-20	Sodium Channel	Neurological Disease Inflammation/Immunology
Nav1.7-IN-20 (Compound 3AG) is an orally active Nav1.7 channel inhibitor with an IC₅₀ of 3.1 μM. Nav1.7-IN-20 demonstrates analgesic efficacy in a complete Freund's adjuvant (CFA) inflammatory pain model. Nav1.7-IN-20 can be used for pain research .

HY-108039R

Bezisterim (Standard) HE 3286 (Standard); NE-3107 (Standard)	Reference Standards NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Bezisterim (Standard) is the analytical standard of Bezisterim (HY-108039). This product is intended for research and analytical applications. Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	상품명

HY-L021M

Natural Product and Natural Product-Like Compound Library	5,019 compounds
From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research. MCE provides a unique collection of 5,019 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

Natural Product and Natural Product-Like Compound Library

5,019 compounds

From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research.

MCE provides a unique collection of 5,019 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

HY-L253

Fungal-Sourced Compound Library	88 compounds
For thousands of years, natural products have always been an important source for drug discovery. Fungi, due to their unique and diverse secondary metabolic capabilities, have become a valuable resource for natural active molecules. Since the discovery of penicillin, natural products derived from fungi have demonstrated significant application value in areas such as anti-infection, anti-tumor, immune regulation, and metabolic disease research. A large number of clinical drugs, such as antibiotics, immunosuppressants, and lipid-lowering drugs, are derived from fungal metabolites or their structurally optimized derivatives. MCE fungal-derived compound library contains 88 structurally diverse and bioactive fungal natural products and their derivatives. It can be widely applied in various research fields such as antibacterial, anti-tumor, anti-inflammatory, immune regulation, epigenetics, and cell signaling pathways, providing high-quality tools for natural product drug development and high-throughput screening.

Fungal-Sourced Compound Library

88 compounds

For thousands of years, natural products have always been an important source for drug discovery. Fungi, due to their unique and diverse secondary metabolic capabilities, have become a valuable resource for natural active molecules. Since the discovery of penicillin, natural products derived from fungi have demonstrated significant application value in areas such as anti-infection, anti-tumor, immune regulation, and metabolic disease research. A large number of clinical drugs, such as antibiotics, immunosuppressants, and lipid-lowering drugs, are derived from fungal metabolites or their structurally optimized derivatives.

MCE fungal-derived compound library contains 88 structurally diverse and bioactive fungal natural products and their derivatives. It can be widely applied in various research fields such as antibacterial, anti-tumor, anti-inflammatory, immune regulation, epigenetics, and cell signaling pathways, providing high-quality tools for natural product drug development and high-throughput screening.

HY-L0094V

Chinese National Compound Library	1,398,968 compounds
The Chinese National Compound Library (CNCL) composes 1.4 million compounds possessing diversified structures. Coupled with this library will be advanced sample handling, information management and quality control systems. Most compounds in the library are drug-like, conforming to “Lipinski’s Rule of Five”, such as MW < 500, logP < 5, Hydrogen Bond Donors < 5.

HY-L939

Antibacterial Lead-like compound library	10855 compounds
The rising prevalence of multidrug-resistant and extensively drug-resistant bacteria, combined with emerging resistance mechanisms and the limitations of existing antibacterial drugs, creates an urgent need for novel antibacterial agents. Antibacterial compound libraries serve as key tools to support antibacterial drug screening and development. This library features structurally diverse compounds, including small-molecule scaffolds and natural product derivatives, and exhibits diverse antibacterial mechanisms of action. For example, these compounds exert antibacterial effects by disrupting bacterial cell structures, interfering with bacterial metabolic processes, and inhibiting nucleic acid synthesis. The derivation of scaffold structures enhances their activity against drug-resistant bacteria and their selectivity against different types of bacteria. This library can be used for the high-throughput screening of novel antibacterial drug candidates and the identification of potent compounds against drug-resistant and multidrug-resistant bacteria. Additionally, it provides a reference for compound structural modification, enabling further in-depth research on the structure-activity relationships(SARs) of antibacterial drugs. It can also be applied to the exploration of bacterial resistance mechanisms and reversal strategies, as well as the discovery of antibacterial molecules that inhibit efflux pumps and restore drug susceptibility. The library contains 10855 structurally diverse drug-like compounds. Its core compound sources include analogs of known antifungal active moleculeswith a similarity score of ≥ 0.6. MCE has collected more than 1900 antibacterial molecules. All screened compounds conform to lead-like physicochemical properties, providing valuable support for the research and development of novel antibacterial drugs.

Antibacterial Lead-like compound library

10855 compounds

The rising prevalence of multidrug-resistant and extensively drug-resistant bacteria, combined with emerging resistance mechanisms and the limitations of existing antibacterial drugs, creates an urgent need for novel antibacterial agents. Antibacterial compound libraries serve as key tools to support antibacterial drug screening and development.

This library features structurally diverse compounds, including small-molecule scaffolds and natural product derivatives, and exhibits diverse antibacterial mechanisms of action. For example, these compounds exert antibacterial effects by disrupting bacterial cell structures, interfering with bacterial metabolic processes, and inhibiting nucleic acid synthesis. The derivation of scaffold structures enhances their activity against drug-resistant bacteria and their selectivity against different types of bacteria. This library can be used for the high-throughput screening of novel antibacterial drug candidates and the identification of potent compounds against drug-resistant and multidrug-resistant bacteria. Additionally, it provides a reference for compound structural modification, enabling further in-depth research on the structure-activity relationships(SARs) of antibacterial drugs. It can also be applied to the exploration of bacterial resistance mechanisms and reversal strategies, as well as the discovery of antibacterial molecules that inhibit efflux pumps and restore drug susceptibility.

The library contains 10855 structurally diverse drug-like compounds. Its core compound sources include analogs of known antifungal active moleculeswith a similarity score of ≥ 0.6. MCE has collected more than 1900 antibacterial molecules. All screened compounds conform to lead-like physicochemical properties, providing valuable support for the research and development of novel antibacterial drugs.

Cat. No.	상품명	Type

HY-112624H

Dextran T2 (MW 2,000) Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)	Biochemical Assay Reagents
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

Dextran T2 (MW 2,000)

Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

Biochemical Assay Reagents

Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-112624E

Dextran T0.8 (MW 800) Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)	Biochemical Assay Reagents
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

Dextran T0.8 (MW 800)

Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)

Biochemical Assay Reagents

Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-W142618

D-Glucal	Biochemical Assay Reagents
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

N-Fmoc-N,O-dimethyl-L-serine	Amino Acid Derivatives	Cancer
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .

trans-N-Methyl-4-methoxyproline	Amino Acid Derivatives	Others
trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative .

Methyl pheophorbide a	Alkaloids Pyrrole Alkaloids Pterocarpus soyauxii Taub. Plants Compositae Source Classification	Photosensitizer Reactive Oxygen Species (ROS) Caspase Apoptosis
Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives. Methyl pheophorbide a is a photosensitizer that produces singlet oxygen and reactive oxygen species (ROS) under light of specific wavelength, thereby leading to cell death .

Frangulin A	Ventilago leiocarpa Benth. Quinones Anthraquinones Plants Rhamnaceae Source Classification	Others
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .

Tropone Cycloheptatrienone	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields Source Classification	Drug Intermediate
Tropone (Cycloheptatrienone) is a non-benzene aromatic natural product and a derivative of a tropane-type compound. Tropone is the direct precursor of various tropane-type natural products, such as Tropolone (HY-N7135) and Tropodithietic acid (HY-N6705), and can be used as a drug intermediate in their biosynthesis .

Indole-3-glyoxylamide 3-Indoleglyoxamide	Structural Classification Alkaloids Solanum melongena L. Solanaceae Plants Indole Alkaloids Source Classification	Others
Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .

Troxerutin (Standard) Trihydroxyethylrutin (Standard)	Flavonoids other families Neurological Disease Classification of Application Fields Phenols Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Source Classification	Reference Standards NOD-like Receptor (NLR)
Troxerutin (Standard) is the analytical standard of Troxerutin. This product is intended for research and analytical applications. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.

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