67 Results for "

Near-infrared fluorescent probe

" in MedChemExpress (MCE) Product Catalog:
Products (67)

67 Results for "Near-infrared fluorescent probe" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-D1063
CAS No.: 207399-07-3
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
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2
2 Cited Publications
Cat. No.: HY-133884
CAS No.: 1686147-55-6
Purity:  99.91%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye .
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1
1 Cited Publications
Cat. No.: HY-D1041
CAS No.: 1622335-40-3
Synonyms: ICG-OSu
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
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1 Cited Publications
Cat. No.: HY-D1464
CAS No.: 1622250-38-7
CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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1 Cited Publications
Cat. No.: HY-W088089
CAS No.: 181934-09-8
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
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1 Cited Publications
Cat. No.: HY-D1719
CAS No.: 95837-47-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .
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1 Cited Publications
Cat. No.: HY-D1719A
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues .
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1 Cited Publications
Cat. No.: HY-D1464A
CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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Cat. No.: HY-103242
CAS No.: 1193447-34-5
Purity:  ≥98.0%
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

CRANAD-2 is a specific near-infrared (NIR) fluorescent probe for detecting plaques (unbound to Aβ: Ex=640 nm; Em=805 nm; after binding: Em=715 nm). CRANAD-2 penetrates the blood-brain barrier and has high affinity for Aβ aggregates, with a Kd value of 38 nM. CRANAD-2 is applicable to research related to Alzheimer's disease and neurodegenerative diseases .
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Cat. No.: HY-145746
CAS No.: 1782950-80-4
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
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Cat. No.: HY-D2365
CAS No.: 304014-13-9
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
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Cat. No.: HY-D2312
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
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Cat. No.: HY-DY1072
CAS No.: 1622335-40-3
Synonyms: ICG-OSu (solution)
ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
Solvent and concentration: DMSO: 10 mM
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Cat. No.: HY-D2864
Aza-CyBz is a NaCl-responsive near-infrared heptamethine cyanine fluorescent probe. Aza-CyBz has an excitation wavelength of 740 nm and detects signals in the range of 760-900 nm. NaCl induces Aza-CyBz to form ordered aggregates, resulting in fluorescence quenching. Aza-CyBz shows no obvious response to interfering substances such as plant carbohydrates, hormones, PEG and ROS. Aza-CyBz can enter plant mitochondria and reflect changes in their salt concentration, and can be used for visual imaging of salt stress in Arabidopsis thaliana root tips and living plants .
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Cat. No.: HY-151890
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
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Cat. No.: HY-D2315
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
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Cat. No.: HY-D2345
GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors .
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Cat. No.: HY-N16309
CAS No.: 3091879-31-8
Category:  

Lipids

Target:  

Fluorescent Dye

Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
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Cat. No.: HY-D0921
CAS No.: 162411-29-2
Synonyms: ADS 815EI
Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
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Cat. No.: HY-W115607
CAS No.: 24991-53-5
Synonyms: Poly(ethylene glycol)-bis-amine 4000
PEG4000-bis-amine (Poly(ethylene glycol)-bis-amine 4000) is a diamine-terminated polyethylene glycol that acts as a linker for conjugate synthesis. PEG4000-bis-amine facilitates the development of MUC1 aptamer-based near-infrared fluorescent probes, and also conjugates folic acid with the near-infrared dye ICG-Der-01 to form a tumor-targeting probe. PEG4000-bis-amine supports the synthesis of folic acid-PEG-DSPE conjugates for the preparation of folic acid-targeted biliposomes. PEG4000-bis-amine is widely used in studies related to breast cancer, non-small cell lung cancer, hepatocellular carcinoma, rheumatoid arthritis, and tumors with high folate receptor expression .
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