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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Norbornene
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Norbornene" in MCE Product Catalog:
Cat. No.: HY-W013021
CAS No.: 498-66-8
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Cat. No.: HY-W440896
DSPE-PEG2000-SH is an amphiphilic thiol-functionalized DSPE-PEG molecule. DSPE-PEG2000-SH inserts into extracellular vesicle (EV) bilayer membranes via hydrophobic interactions, displaying surface thiol groups to form EV-SH crosslinkers.DSPE-PEG2000-SH enables crosslinking of EV-SH with 8-arm PEG-norbornene via thiol-ene photochemistry to construct hydrogels, with hydrogel mechanical properties tunable via PEG segment molecular weight variation.DSPE-PEG2000-SH can be used to encapsulate agents for drug delivery system, such as mRNA vaccine .
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Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation .
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Poly (ethylene glycol) dithiol (Mn 3400) is a bifunctional thiol-terminated PEG crosslinking and polymerization reagent. The terminal thiol groups of Poly (ethylene glycol) dithiol (Mn 3400) can undergo thiol-ene photochemical click reactions with norbornene groups, thereby crosslinking to form hydrogel networks; it can also serve as a dithiol monomer in the step-growth polymerization of hexahydrotriazine (HT) to form poly (thioaminal) polymers containing dynamic thioacetal bonds. Poly (ethylene glycol) dithiol (Mn 3400) is applicable for hydrogel construction, biomanufacturing, and dynamic covalent polymer research .
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ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research .
Cat. No.: HY-151742
CAS No.: 1986791-87-0
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Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine .
Cat. No.: HY-151682
CAS No.: 1378916-76-7
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H-L-Lys(Norbornene-methoxycarbonyl)-OH is a Norbornene (HY-W013021)-derivatized lysine that can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .
Cat. No.: HY-151682A
CAS No.: 2560614-20-0
Cat. No.: HY-128478
CAS No.: 11076-17-8
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Cat. No.: HY-W013021R
CAS No.: 498-66-8
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Cat. No.: HY-182840A
Cat. No.: HY-182840B
Cat. No.: HY-W1048695A
Cat. No.: HY-W1048695B
Cat. No.: HY-W1048695C
Cat. No.: HY-W1048695E
Cat. No.: HY-W022007
CAS No.: 95-10-3
Synonyms: JBP
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5-Norbornene-2-methylamine (JBP) is a hydrophobic tag. 5-Norbornene-2-methylamine can be used for the synthesis of HyT degraders, such as PARP1 degrader-2 (HY-181460) .
Cat. No.: HY-181908
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5-Norbornene-2-methylamine-C10-NH2 is a Keap1-targeting hydrophobic tag (HyT)-linker conjugates, containing a HyT (HY-W022007) and a linker (HY-W014831). 5-Norbornene-2-methylamine-C10-NH2 can be used for synthesis of NBE5 (HY-181907) .
Cat. No.: HY-D2957
CAS No.: 3074567-08-8
Synonyms: NorBG; SNAP-Nor
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
