50 Results for "

OX40L

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "OX40L" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99434
CAS No.: 2378692-15-8
Synonyms: KY1005; SAR445229

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Amlitelimab () is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Amlitelimab inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis .
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1
1 Cited Publications
Cat. No.: HY-P78189
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD134; OX40; OX40L receptor; TNFRSF4; ACT-135; Ly-70; OX40 homologue;  TXGP1L; IMD16
Species:  
Source:  
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Cat. No.: HY-P99408
CAS No.: 1186098-83-8
Synonyms: R 4930; huMAb OX 40L; Ro 49-89991

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma .
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Cat. No.: HY-P990907
CAS No.: 2834733-45-6
Synonyms: F-027300252; SAR-442970

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Brivekimig (F-027300252; SAR-442970) is a bispecific nanobody targeting TNF/OX40L. Brivekimig is applicable to research related to hidradenitis suppurativa.
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Cat. No.: HY-P99249
CAS No.: 1638935-72-4
Synonyms: Pogalizumab; MOXR 0916

Research Areas:  

Cancer

Vonlerolizumab (Pogalizumab; MOXR 0916) is a humanized IgG1 monoclonal antibody targeting OX40 (CD134). Pogalizumab partially blocks the interaction between OX40 and its natural ligand OX40L upon binding, thereby activating the NF-κB signaling pathway. Pogalizumab enhances T cell activation and proliferation and has shown antitumor activity in mouse models .
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Cat. No.: HY-P990175
Anti-Mouse OX40L/CD134L Antibody (RM134L) is an anti-mouse OX40L/CD134L IgG2b monoclonal antibody. Anti-Mouse OX40L/CD134L Antibody (RM134L) reduces immune response by inhibiting the OX40/OX40L signaling pathway. Anti-Mouse OX40L/CD134L Antibody (RM134L) can inhibit plasma cell differentiation and antibody secretion. Anti-Mouse OX40L/CD134L Antibody (RM134L) can prolong the survival time of cell transplantation by inhibiting CD4 + T cells. Anti-Mouse OX40L/CD134L Antibody (RM134L) can be used for researches on inflammation and cancer such as graft versus host disease (GVHD), allergic reaction, lupus nephritis and hepatocellular carcinoma (HCC) .
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Cat. No.: HY-P99836
CAS No.: 2244739-29-3
Synonyms: IBI101
Cudarolimab (IBI101) is a completely human anti-OX40 (CD134, a co stimulating molecule expressed by activated immune cells) antibody. Cudarolimab inhibits the binding of OX40 to its ligand OX40L. Cudarolimab has antitumor activity and can be used in cancer related research .
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Cat. No.: HY-P991614

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

IBI356 is a humanized monoclonal antibody inhibitor targeting OX40L/CD134L/CD252. IBI356 can be used to study chronic inflammatory skin diseases, such as atopic dermatitis .
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Cat. No.: HY-P700306
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: OX40L; OX-40L; OX4OL; CD252; TNFSF4; OX40 Ligand; CD134 ligand; CD134L;  TXGP1; Glycoprotein Gp34
Species:  
Source:  
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Cat. No.: HY-P704291
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: OX40L; OX-40L; OX4OL; CD252; TNFSF4; OX40 Ligand; CD134 ligand; CD134L;  TXGP1; Glycoprotein Gp34
Species:  
Source:  
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Cat. No.: HY-P78504
Purity:  ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: OX40L; OX-40L; OX4OL; CD252; TNFSF4; OX40 Ligand; CD134 ligand; CD134L;  TXGP1; Glycoprotein Gp34
Species:  
Source:  
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Cat. No.: HY-P99911
CAS No.: 1635395-27-5
Synonyms: MEDI-6383
Efizonerimod alfa (MEDI-6383) is a recombinant human OX40L IgG4P Fc fusion protein that assembles into a hexameric structure and exerts potent agonist activity upon binding to OX40. The activity of Efizonerimod alfa is enhanced by Fcγ receptor-mediated aggregation. Efizonerimod alfa binds to OX40 on the surface of activated T cells, induces NF-κB promoter activity in OX40-expressing T cells, and triggers the production of Th1-type cytokines, T cell proliferation, and resistance to regulatory T cell (Treg)-mediated suppression. Efizonerimod alfa enhances the cytolytic activity of tumor-reactive T cells and slows tumor growth in immunodeficient mice. Efizonerimod alfa induces the proliferation of CD4, CD8, and B cells in the peripheral blood of healthy non-human primates. Efizonerimod alfa can be used in the research of advanced solid malignancies and melanoma .
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Cat. No.: HY-P81730
Synonyms: TNFSF4; TXGP1; Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; CD antigen CD252

Host:  

Rabbit

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P810813
Synonyms: CD252, TXGP1, TNFSF4, Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, TAX transcriptionally-activated glycoprotein 1, OX40L

Host:  

Mouse

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P77460
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD134L; CD252; Glycoprotein Gp34; OX40 antigen ligand; OX40L; TXGP1
Species:  
Source:  
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Cat. No.: HY-P704832
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD134L; CD252; Glycoprotein Gp34; OX40 antigen ligand; OX40L; TXGP1
Species:  
Rat
Source:  
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Cat. No.: HY-P77458
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD134L; CD252; Glycoprotein Gp34; OX40 antigen ligand; OX40L; TXGP1
Species:  
Source:  
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Cat. No.: HY-P77459
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD134L; CD252; Glycoprotein Gp34; OX40 antigen ligand; OX40L; TXGP1
Species:  
Source:  
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Cat. No.: HY-P74660
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD134L; CD252; Glycoprotein Gp34; OX40 antigen ligand; OX40L; TXGP1
Species:  
Rat
Source:  
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Cat. No.: HY-P992435

Target:  

TNF Receptor

Research Areas:  

Cancer

OX118 is a fully human, ADCC-enhanced monoclonal antibody targeting OX40L, the recommended isotype control is HY-P99001. OX118 blocks OX40L, suppresses effector T-cell proliferation, expands regulatory T-cell populations, and reduces bystander activation across natural killer cells, B cells, and CD14+ monocytes. OX118 can be used for the research of graft-versus-host disease .
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