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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
P22
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "P22" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
THX-B is a potent and non-peptidic p75 NTR (neurotrophin receptor p75) antagonist. THX-B can be used in the research of diabetic kidney disease, neurodegenerative and inflammatory disorders .
Synonyms: DAQ B1; L-783281; Dimethylasterriquinone
Target:
Insulin Receptor Akt NO Synthase NADPH Oxidase JAK STAT FOXO DNA/RNA Synthesis ERK Flavivirus
Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology
Demethylasterriquinone B1 (DAQ B1; L-783281) is an orally active insulin receptor (insulin receptor) agonist and AKT activator. By activating AKT, Demethylasterriquinone B1 upregulates the expression and activity of eNOS to increase NO production, while downregulating the expression of the NADPH oxidase subunit p22phox to reduce oxidative stress and improve vascular endothelial dysfunction in hypertensive rats. Demethylasterriquinone B1 combind with an AKT inhibitor targets the insulin signaling pathway to activate two antiviral pathways, RNA interference and JAK/STAT, in mosquitoes, thereby reducing Zika virus infection .
Cat. No.: HY-P99620
CAS No.: 1443004-15-6
Synonyms: CT-P22; CT120
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Cat. No.: HY-P11040
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NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells .
Cat. No.: HY-165116
CAS No.: 206059-98-5
Synonyms: 18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)
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1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.
Cat. No.: HY-157695
CAS No.: 799268-64-7
Synonyms: C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC
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1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.
Cat. No.: HY-156425
CAS No.: 2648709-79-7
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NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells .
Cat. No.: HY-N16527
CAS No.: 233690-85-2
Cat. No.: HY-172733S
CAS No.: 3052146-54-7
Cat. No.: HY-RS02652
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CHP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10408
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PHB2 Human Pre-designed siRNA Set A contains three designed siRNAs for PHB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1331
CAS No.: 76622-26-9
Synonyms: Bovine adrenal medulla-22P
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Cat. No.: HY-RS04082
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DYNC1H1 Human Pre-designed siRNA Set A contains three designed siRNAs for DYNC1H1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
