29 Results for "

PEPT1

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "PEPT1" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B1190
CAS No.: 50370-12-2
Synonyms: BL-S 578
Target:  

Bacterial Antibiotic EAAT

Research Areas:  

Infection Neurological Disease

Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain [1] .
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5
5 Cited Publications
Cat. No.: HY-B1190A
CAS No.: 66592-87-8
Synonyms: BL-S 578 hydrate
Target:  

Bacterial Antibiotic EAAT

Research Areas:  

Infection Neurological Disease

Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain [1] .
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1
1 Cited Publications
Cat. No.: HY-B1258
CAS No.: 56-91-7
Synonyms: Aminomethylbenzoic acid; α-Amino-p-toluic acid
Research Areas:  

Cancer

4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity [1].
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1
1 Cited Publications
Cat. No.: HY-111956B
CAS No.: 2703746-41-0
Purity:  98.77%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) [1] .
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Cat. No.: HY-W010162
CAS No.: 1948-31-8
Synonyms: L-Alanyl-L-alanine; Ala-Ala
H-Ala-Ala-OH is a substrate of human intestinal oligopeptide transporter (PEPT1/SLC15A1), with an IC50 of 0.25 mM and an EC50 of 0.08 mM against human PEPT1. When used as a dipeptide linker in antibody-drug conjugates (ADCs) loaded with glucocorticoid receptor regulator payloads, H-Ala-Ala-OH enables efficient intracellular payload release [1] .
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Cat. No.: HY-Y1080
CAS No.: 19764-30-8
Synonyms: N-Acetyl-D-leucine
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC50 of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies [1] .
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Cat. No.: HY-W011165
CAS No.: 52123-30-5
Synonyms: L-Lysyl-L-lysine dihydrochloride
Lysyllysine dihydrochloride (L-Lysyl-L-lysine dihydrochloride) is an orally active PepT1 substrate. Lysyllysine dihydrochloride enhances whole-body protein synthesis, improves intestinal structure, alleviates intestinal mucosal inflammation, and exhibits higher lysine bioavailability in neonatal piglets with PN-induced intestinal atrophy. Lysyllysine dihydrochloride inhibits the growth of axenic cyanobacterial strains and induces their cell lysis. Lysyllysine dihydrochloride can be used in studies related to intestinal atrophy and metabolism [1] .
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Cat. No.: HY-111956
CAS No.: 375822-19-8
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) [1] .
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Cat. No.: HY-W327145
CAS No.: 45234-02-4
Target:  

Endogenous Metabolite

Research Areas:  

Infection

Lysylglutamic acid is a dipeptide formed by combining two amino acids, Lysine (Lys) and Glutamic acid (Glu). The Ki value of the membrane transporter PEPT1 was 1.3 mM [1].
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Cat. No.: HY-B1190R
CAS No.: 50370-12-2
Synonyms: BL-S 578 (Standard)
Cefadroxil (Standard) is the analytical standard of Cefadroxil (HY-B1190). This product is intended for research and analytical applications. Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain [1] .
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Cat. No.: HY-105040C
CAS No.: 635318-26-2
Purity:  ≥98.0%
Synonyms: LY2140023 hydrochloride
Target:  

mGluR

Research Areas:  

Neurological Disease

Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research [1] .
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Cat. No.: HY-120791
CAS No.: 13184-13-9
Synonyms: L-Lysyl-L-lysine
Lysyllysine (L-Lysyl-L-lysine ) is an orally active PepT1 substrate. Lysyllysine enhances whole-body protein synthesis, improves intestinal structure, alleviates intestinal mucosal inflammation, and exhibits higher lysine bioavailability in neonatal piglets with PN-induced intestinal atrophy. Lysyllysine inhibits the growth of axenic cyanobacterial strains and induces their cell lysis. Lysyllysine can be used in studies related to intestinal atrophy and metabolism [1] .
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Cat. No.: HY-111956A
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) [1] .
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Cat. No.: HY-B1190S
CAS No.: 1426174-38-0
Synonyms: BL-S 578-d4 hydrate
Cefadroxil-d4 (hydrate) is the deuterium labeled Cefadroxil hydrate (HY-B1190A). Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain [1] .
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Cat. No.: HY-P703219
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PEPT1
Species:  
Source:  
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Cat. No.: HY-117110
CAS No.: 2418-69-1
Synonyms: H-Arg-Pro-OH
Target:  

Proton Pump

Research Areas:  

Metabolic Disease

Arginylproline (H-Arg-Pro-OH) is a dipeptide consisted of arginine and proline. Arginylproline reduces intracellular triglyceride (TG) levels stimulated by Oleic acid (HY-N1446), through the peptide transporter 1 (PepT1) pathway [1].
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Cat. No.: HY-B1258S
Synonyms: Aminomethylbenzoic acid-13C2,15N; α-Amino-p-toluic acid-13C2,15N
Intermediate of tranexamic Acid- 13C2, 15N (Aminomethylbenzoic acid- 13C2, 15N) is 13C and 15N labeled 4-(Aminomethyl)benzoic acid. 4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity [1].
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Cat. No.: HY-P4296
CAS No.: 57836-11-0
Research Areas:  

Others

H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation [1] .
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Cat. No.: HY-B2072AR
CAS No.: 102039-86-1
Research Areas:  

Infection

Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil (hydrate). This product is intended for research and analytical applications. Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 [1] .
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Cat. No.: HY-184037
CAS No.: 643755-41-3
Research Areas:  

Others

Alanyl ornithine is a PEPT1 (mammalian H +/peptide cotransporter) ligand with a binding affinity for this transporter (Ki = 0.97 mM). Alanyl ornithine serves as a reference molecule for studies on the substrate recognition mechanism of PEPT1 [1].
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