16 Results for "

PICK1

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "PICK1" in MCE Product Catalog:

Cat. No.: HY-117772
CAS No.: 1215849-96-9
Purity:  99.84%
Target:  

iGluR

FSC231 is a PSD‐95/DLG/ZO‐1 (PDZ) domain inhibitor of PICK1. FSC231 has analgesic effects [1].
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Cat. No.: HY-RS10479
Research Areas:  

Others

PICK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PICK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23656
Research Areas:  

Others

Pick1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pick1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-180197
PICK1 PDZ-IN-1 (Compound 6b) is a selective and brain-penetrant protein interacting with C kinase 1 (PICK1) PDZ domain inhibitor with a Ki of 27.73 μM. PICK1 PDZ-IN-1 can competitively inhibit the interaction between PICK1 and the GluA2 subunit of AMPA receptors. PICK1 PDZ-IN-1 can increase the survival rate of HT22 cells and primary cortical neuron cells induced by glutamate and inhibit ROS production. PICK1 PDZ-IN-1 exhibits neuroprotective effect and reduces the area of cerebral infarction. PICK1 PDZ-IN-1 can be used for the research of ischemic stroke [1].
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Cat. No.: HY-RS17204
Research Areas:  

Others

Pick1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pick1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1054
CAS No.: 1315378-67-6
Synonyms: YNVYGIEEVKI
Target:  

PKC

Research Areas:  

Neurological Disease

pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression [1].
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Cat. No.: HY-P2298
Target:  

PKC

Research Areas:  

Neurological Disease

TAT-P4-(DATC5)2 is a high-affinity peptide inhibitor of the PICK1 (protein interacting with C kinase-1) PDZ domain, with a Ki of 1.7 nM. TAT-P4-(DATC5)2 can inhibit addiction in rats [1].
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Cat. No.: HY-P2298A
Target:  

PKC

Research Areas:  

Neurological Disease

TAT-P4-(DATC5)2 TFA is a high-affinity peptide inhibitor of the PICK1 (protein interacting with C kinase-1) PDZ domain, with a Ki of 1.7 nM. TAT-P4-(DATC5)2 TFA can inhibit addiction in rats [1].
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Cat. No.: HY-P81887
Synonyms: PICK 1; PICK1; PRKCABP

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81887A
Synonyms: PICK 1; PICK1; PRKCABP

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P1057
CAS No.: 243843-43-8
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity [1] [2] [3] [4] [5] [6].
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Cat. No.: HY-P810487
Synonyms: PICK 1, PICK1, PRKCABP

Host:  

Rabbit

Application:  

WB, FC, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P1055
CAS No.: 1315378-76-7
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ 3H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD [1] [2] [3] [4] [5].
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Cat. No.: HY-P703269
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PRKCABP
Species:  
Source:  
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Cat. No.: HY-P1059
CAS No.: 1315378-69-8
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep2-AVKI is a selective peptide inhibitor of the binding of the AMPA receptor subunit (GluR2) at the C-terminal PDZ site to C-kinase (PICK1). Pep2-AVKI does not affect the binding of (AMPA-type glutamate receptor) GluA2 to GRIP or ABP. Pep2-AVKI does not increase the amplitude of AMPA currents. pep2-AVKI can be used to study neurological diseases [1] .
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Cat. No.: HY-P1056
CAS No.: 328944-75-8
Target:  

iGluR

Research Areas:  

Neurological Disease

pep2-SVKI is a selective peptide inhibitor. pep2-SVKI inhibits the binding of AMPA-type glutamate receptor (GluA2) (C-terminal PDZ site) to glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP), and C-kinase interacting protein (PICK1). pep2-SVKI increases the amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD). pep2-SVKI can be used to study neurological diseases [1] .
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