TAT-P4-(DATC5)2
TAT-P4-(DATC5)2 is a high-affinity peptide inhibitor of the PICK1 (protein interacting with C kinase-1) PDZ domain, with a Ki of 1.7 nM. TAT-P4-(DATC5)2 can inhibit addiction in rats.
For research use only. We do not sell to patients.
- Formula: C150H246N52O32
- Molecular Weight:3289.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ki: 1.7 nM (PICK1 PDZ domain)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (250-300 g) [1]
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Dosage:0.99 μg/kg, 9.9 μg/kg
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Administration:Infused intravenously, 45 min prior to an acute injection of cocaine (10 mg/kg, i.p.)
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Result:Attenuated the reinstatement of cocaine seeking in rats.
Chemical Information
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Molecular Weight 3289.95
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Formula C150H246N52O32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)