25 Results for "

POMC

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "POMC" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-P0252
CAS No.: 581-05-5
Synonyms: α-Melanocyte-Stimulating Hormone
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .
loading...
    loading...
24
24 Publications Verification
Cat. No.: HY-P0252A
CAS No.: 171869-93-5
Synonyms: α-Melanocyte-Stimulating Hormone TFA
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC) .
loading...
    loading...
17
17 Cited Publications
Cat. No.: HY-N6733
CAS No.: 38966-21-1
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P2281A
Synonyms: Atrial natriuretic peptide (1-28) TFA
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
loading...
    loading...
Cat. No.: HY-117787
CAS No.: 1390641-90-3
TUG-905 is a potent GPR40 agonist with an pEC50 value of 7.03. TUG-905 increases hypothalamic cell proliferation and survival. TUG-905 reduces body mass and increases the POMC mRNA expression .
loading...
    loading...
Cat. No.: HY-P1922
CAS No.: 799841-81-9
Target:  

Melanocortin Receptor

Research Areas:  

Endocrinology

γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands .
loading...
    loading...
Cat. No.: HY-P4779
CAS No.: 1815617-98-1
Target:  

Androgen Receptor

Research Areas:  

Neurological Disease

Acetyl-ACTH (2-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
loading...
    loading...
Cat. No.: HY-P4786
CAS No.: 1815618-01-9
Target:  

Androgen Receptor

Acetyl-ACTH (7-24) (human, bovine, rat) causes a marked decrease of ACTH-evoked corticosterone and aldosterone release .
loading...
    loading...
Cat. No.: HY-121859
CAS No.: 74915-64-3
Research Areas:  

Metabolic Disease

RU28362 is a potent and selective glucocorticoid agonist. RU28362 increases the Bnip3 mRNA levels in neurons. RU28362 inhibits adrenocorticotrophic hormone (ACTH) and corticosterone secretion . RU28362 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...
Cat. No.: HY-RS10865
Research Areas:  

Others

POMC Human Pre-designed siRNA Set A contains three designed siRNAs for POMC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS17248
Research Areas:  

Others

Pomc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pomc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS23702
Research Areas:  

Others

Pomc Rat Pre-designed siRNA Set A contains three designed siRNAs for Pomc gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-N6733R
CAS No.: 38966-21-1
Aphidicolin (Standard) is the analytical standard of Aphidicolin. This product is intended for research and analytical applications. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
loading...
    loading...
Cat. No.: HY-P4782
CAS No.: 1815617-99-2
Target:  

Androgen Receptor

Research Areas:  

Neurological Disease

Acetyl-ACTH (3-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
loading...
    loading...
Cat. No.: HY-P4784
CAS No.: 1815618-00-8
Target:  

Androgen Receptor

Research Areas:  

Neurological Disease

Acetyl-ACTH (4-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
loading...
    loading...
Cat. No.: HY-P2281
CAS No.: 91917-63-4
Synonyms: Atrial natriuretic peptide (1-28)
Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
loading...
    loading...
Cat. No.: HY-P4985
CAS No.: 72629-64-2
Target:  

Melanocortin Receptor

Research Areas:  

Neurological Disease

γ3-MSH is derived from the N-terminal segment of pro-opiomelanocortin (POMC). γ3-MSH stimulates aldosterone secretion by human adrenal tumor cells in culture .
loading...
    loading...
Cat. No.: HY-P3658
CAS No.: 78859-45-7
Target:  

Peptides

Research Areas:  

Others

[Lys0]γ1-MSH is a γ1-melanotropin-like peptide, one of 1600-dalton γ-MSHs. [Lys0]γ1-MSH can be isolated from bovine neurointermediate pituitary lobes .
loading...
    loading...
Cat. No.: HY-P1210
CAS No.: 156159-18-1
Target:  

Melanocortin Receptor

Research Areas:  

Endocrinology

Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .
loading...
    loading...
Cat. No.: HY-P1210A
Target:  

Melanocortin Receptor

Research Areas:  

Endocrinology

Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .
loading...
    loading...