81 Results for "

PSI

" in MedChemExpress (MCE) Product Catalog:
Products (81)

81 Results for "PSI" in MCE Product Catalog:

Cat. No.: HY-P1258
CAS No.: 158442-41-2
Synonyms: Proteasome Inhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO
Target:  

Proteasome

Research Areas:  

Infection Cancer

PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas .
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120
120 Publications Verification
Cat. No.: HY-15005
CAS No.: 1190307-88-0
Purity:  99.97%
Synonyms: GS-7977; PSI-7977
Target:  

HCV

Research Areas:  

Infection Cancer

Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM .
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9
9 Cited Publications
Cat. No.: HY-15526
CAS No.: 851546-61-7
Purity:  99.79%
Synonyms: P-Selectin Inhibitor
Target:  

P-selectin

Research Areas:  

Cancer

PSI-697 is an oral P-selectin inhibitor with an IC50 of 125 μM .
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8
8 Cited Publications
Cat. No.: HY-15745A
CAS No.: 1621884-22-7
Purity:  99.31%
Target:  

HCV

Research Areas:  

Infection

PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
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7
7 Cited Publications
Cat. No.: HY-10240
CAS No.: 940908-79-2
Purity:  99.07%
Synonyms: RG 7128; R-7128; PSI 6130 diisobutyrate
Target:  

HCV

Research Areas:  

Infection

Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
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3
3 Cited Publications
Cat. No.: HY-15236
CAS No.: 863329-66-2
Purity:  99.89%
Synonyms: RO 2433; GS-331007
Target:  

HCV

Research Areas:  

Infection

PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.
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2
2 Cited Publications
Cat. No.: HY-10165
CAS No.: 817204-33-4
Purity:  99.39%
Synonyms: R 1656
Target:  

HCV

Research Areas:  

Infection

PSI-6130 is a potent and selective inhibitor of HCV NS5B polymerase, and inhibits HCV replication with a mean IC50 of 0.6 μM.
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1
1 Cited Publications
Cat. No.: HY-15005S1
CAS No.: 1868135-06-1
Purity:  98.35%
Synonyms: PSI-7977-d6; GS-7977-d6
Sofosbuvir-d6 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
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1
1 Cited Publications
Cat. No.: HY-15005R
CAS No.: 1190307-88-0
Synonyms: GS-7977 (Standard); PSI-7977 (Standard)
Target:  

Reference Standards HCV

Research Areas:  

Infection

Sofosbuvir (Standard) is the analytical standard of Sofosbuvir. This product is intended for research and analytical applications. Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM .
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Cat. No.: HY-153079
Purity:  97.00%
Target:  

mRNA

Research Areas:  

Others

eGFP mRNA (N1-Me-Pseudo UTP) will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response.
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Cat. No.: HY-P2389
CAS No.: 957780-54-0
Research Areas:  

Others

Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
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Cat. No.: HY-P2407
CAS No.: 1000164-43-1
Research Areas:  

Others

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
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Cat. No.: HY-P2402
CAS No.: 1262308-49-5
Research Areas:  

Others

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a protected amino acid derivative and building block. Fmoc-Gly-Thr(psi(Me,Me)pro)-OH can be used in peptide synthesis .
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Cat. No.: HY-15745
CAS No.: 1015073-42-3
Target:  

HCV

Research Areas:  

Cancer

PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV.
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Cat. No.: HY-P2405
CAS No.: 1095952-22-9
Research Areas:  

Others

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a side-chain protected amino acid building block. Fmoc-Gly-Ser(psi(Me,Me)pro)-OH can be used for peptide synthesis .
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Cat. No.: HY-P2410
CAS No.: 1147996-34-6
Research Areas:  

Others

Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide.
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Cat. No.: HY-P2399
CAS No.: 957780-56-2
Research Areas:  

Others

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide building block containing a pseudoproline, which is used in studies related to Fmoc solid-phase peptide synthesis. Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH inhibits premature β-sheet aggregation during solid-phase peptide synthesis .
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Cat. No.: HY-15005A
CAS No.: 1190308-01-0
Purity:  98.24%
Target:  

HCV

Research Areas:  

Infection

PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
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Cat. No.: HY-14391
CAS No.: 1231747-08-2
Synonyms: GS-558093
Target:  

HCV

Research Areas:  

Infection

PSI-353661 (GS-558093) is a purine nucleotide NS5B polymerase inhibitor against HCV infection. PSI-353661 shows EC90s of 8 nM and 11 nM for wild type and S282T resistant replicons of HCV. PSI-353661 can produce high concentrations of the active triphosphate in primary human hepatocytes .
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Cat. No.: HY-P2398
CAS No.: 878797-01-4
Research Areas:  

Others

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is a pseudo-proline dipeptide building block corresponding to positions 27-28 of the teduglutide sequence. Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is applied in solid-phase peptide synthesis. Fmoc-Phe-Ser(psi(Me,Me)pro)-OH can be used for the research of teduglutide synthesis .
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