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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
PTH1R
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "PTH1R" in MCE Product Catalog:
Cat. No.: HY-P4385
CAS No.: 129622-68-0
Target:
Research Areas:
Cat. No.: HY-176946
CAS No.: 3106619-54-6
Target:
Research Areas:
PTH1R agonist 4 (Example 63) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value greater than 7. PTH1R agonist 4 can be used for the study of bone diseases, such as osteoporosis [1].
Cat. No.: HY-RS11395
Target:
Research Areas:
PTH1R Human Pre-designed siRNA Set A contains three designed siRNAs for PTH1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176944
CAS No.: 3106850-44-3
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PTH1R agonist 2 (example 3) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 2 can be used for research of hypoparathyroidism and osteoporosis [1].
Cat. No.: HY-176945
CAS No.: 3106619-38-6
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Research Areas:
PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis [1].
Cat. No.: HY-P3075
CAS No.: 112540-82-6
Synonyms: PTHrP (1-34)
Target:
PTHR PKA PKC PI3K Akt ERK NADPH Oxidase Reactive Oxygen Species (ROS) TGF-beta/Smad Caspase Apoptosis NO Synthase
Research Areas:
pTH-Related Protein (1-34) (human,mouse,rat) (pTHrP (1-34)) is a parathyroid hormone-related protein fragment. Binding of pTH-Related Protein (1-34) (human,mouse,rat) to PTH1R triggers cAMP/PKA and PKC signaling, PI3K-mediated Akt and ERK1/2 phosphorylation, NADPH oxidase-dependent ROS generation, and TGF-beta1 and p47phox expression. pTH-Related Protein (1-34) (human,mouse,rat) induces fibronectin upregulation, osteoblast differentiation, osteoclastic bone resorption, bone formation, eNOS/NO-mediated vasodilation, and sensitization of type II pneumocytes to ultraviolet-induced apoptosis (apoptosis) via caspase 3. pTH-Related Protein (1-34) (human,mouse,rat) can be used in research on diabetic nephropathy, breast cancer, acute lung injury, humoral hypercalcemia of malignancy, osteoporosis, and cartilage degeneration [1] .
Cat. No.: HY-176943
CAS No.: 3106336-35-7
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PTH1R agonist 1 (Example 2) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 1 can be used for research of hypoparathyroidism and osteoporosis [1].
Cat. No.: HY-RS17667
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Research Areas:
Pth1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pth1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-131206
CAS No.: 2460353-87-9
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DS37571084 is an orally active competitive antagonist of parathyroid hormone receptor 1 (PTH1R) with an IC50 value of 0.17 μM. DS37571084 is applicable to the research of bone diseases and calcium metabolism disorders associated with primary hyperparathyroidism [1] .
Cat. No.: HY-RS24128
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Research Areas:
Pth1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Pth1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705968
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTH1R; PTH/PTHr Receptor; Prev. PTHR1; Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor; Prev. PTHR; Seven Transmembrane Helix Receptor; Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor; EKNS; PTH/PTHrP Type I Receptor; PFE
Species:
Rat
Source:
HEK293
Cat. No.: HY-P71244
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTH1R; PTH/PTHr Receptor; Prev. PTHR1; Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor; Prev. PTHR; Seven Transmembrane Helix Receptor; Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor; EKNS; PTH/PTHrP Type I Receptor; PFE
Species:
Human
Source:
HEK293
Cat. No.: HY-179356
CAS No.: 1413439-62-9
Target:
Research Areas:
Octadecyl β-D-glucopyranosiduronic acid (Compound 9) is a parathyroid hormone 1 receptor (PTH1R) activator, with a pEC50 value > 9. Octadecyl β-D-glucopyranosiduronic acid can be used for research on hypoparathyroidism [1].
Cat. No.: HY-P705535
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTH1R; PTH/PTHr Receptor; Prev. PTHR1; Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor; Prev. PTHR; Seven Transmembrane Helix Receptor; Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor; EKNS; PTH/PTHrP Type I Receptor; PFE
Species:
Cynomolgus
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
