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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
PTS
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "PTS" in MCE Product Catalog:
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Research Areas:
Allyl thiosulfate (Sodium 2-propenyl thiosulfate) is found in Allium plants such as garlic and onion. Allyl thiosulfate can inhibit COX activity and reduce GSH concentration in platelets. Allyl thiosulfate exhibits anti-aggregatory and anti-cancer effects. Allyl thiosulfate can be used for the researches of cancer, inflammation and cardiovascular disease .
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F-14512 is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 can be used to study breast cancer .
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N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate can be hydrolyze by NagA .
Cat. No.: HY-P10230
CAS No.: 207410-26-2
Cat. No.: HY-RS11455
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PTS Human Pre-designed siRNA Set A contains three designed siRNAs for PTS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-106031A
CAS No.: 866874-39-7
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Research Areas:
F-14512 hydrochloride is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 hydrochloride enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 hydrochloride exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 hydrochloride demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 hydrochloride could be used to study breast cancer .
Cat. No.: HY-116259
CAS No.: 1356497-92-1
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PT-S58, a GSK0660 derivative, is a PPARβ/δ full antagonist with an IC50 value of 98 nM. PT-S58 inhibits the agonist-induced transcriptional activity of PPARβ/δ in vitro .
Cat. No.: HY-RS20244
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Research Areas:
Pts Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26752
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Pts Rat Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-143456
CAS No.: 2873386-66-2
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Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC50 of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
Cat. No.: HY-143457
CAS No.: 2873386-63-9
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Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC50 of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
Cat. No.: HY-W601362
CAS No.: 102029-88-9
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Research Areas:
N-Acetyl-D-galactosamine-6-phosphate disodium is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate disodium can be hydrolyze by NagA .
Cat. No.: HY-N19420
CAS No.: 89013-69-4
Cat. No.: HY-184387
CAS No.: 2552327-34-9
Pleuromutilin conjugate T7 is a broad-spectrum antibacterial agent. Pleuromutilin conjugate T7 inhibits bacterial energy uptake, reverses drug efflux, interferes with carbohydrate metabolism, inhibits protein synthesis, disrupts biofilms, impairs cell membrane integrity, and attenuates the functions of virulence and adhesion factors. Pleuromutilin conjugate T7 can be used in studies related to Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) infections, multidrug-resistant Enterococcus faecalis infections, and Gram-negative bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
