PTS

By Targets:	Bacterial (2) Biochemical Assay Reagents (1) COX (1) DNA/RNA Synthesis (2) Endogenous Metabolite (1) Interleukin Related (1) NO Synthase (2) PPAR (1) Renin (1) Small Interfering RNA (siRNA) (3) TNF Receptor (1) Topoisomerase (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (4) Metabolic Disease (3)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-178872

Allyl thiosulfate Sodium 2-propenyl thiosulfate; 2PTS	COX	Inflammation/Immunology Cancer
Allyl thiosulfate (Sodium 2-propenyl thiosulfate) is found in Allium plants such as garlic and onion. Allyl thiosulfate can inhibit COX activity and reduce GSH concentration in platelets. Allyl thiosulfate exhibits anti-aggregatory and anti-cancer effects. Allyl thiosulfate can be used for the researches of cancer, inflammation and cardiovascular disease .

HY-106031

F-14512	Topoisomerase DNA/RNA Synthesis	Cancer
F-14512 is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 can be used to study breast cancer .

HY-147062

N-Acetyl-D-galactosamine-6-phosphate	Biochemical Assay Reagents	Metabolic Disease
N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate can be hydrolyze by NagA .

HY-P10230

Sublancin	Bacterial	Infection
Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .

HY-RS11455

PTS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTS Human Pre-designed siRNA Set A contains three designed siRNAs for PTS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTS Human Pre-designed siRNA Set A PTS Human Pre-designed siRNA Set A

HY-106031A

F-14512 hydrochloride	Topoisomerase DNA/RNA Synthesis	Cancer
F-14512 hydrochloride is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 hydrochloride enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 hydrochloride exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 hydrochloride demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 hydrochloride could be used to study breast cancer .

HY-116259

PT-S58	PPAR	Metabolic Disease
PT-S58, a GSK0660 derivative, is a PPARβ/δ full antagonist with an IC₅₀ value of 98 nM. PT-S58 inhibits the agonist-induced transcriptional activity of PPARβ/δ in vitro .

HY-RS26752

Pts Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pts Rat Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pts Rat Pre-designed siRNA Set A Pts Rat Pre-designed siRNA Set A

HY-RS20244

Pts Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pts Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pts Mouse Pre-designed siRNA Set A Pts Mouse Pre-designed siRNA Set A

HY-143456

Anti-inflammatory agent 18	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC₅₀ of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-143457

Anti-inflammatory agent 19	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC₅₀ of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-W601362

N-Acetyl-D-galactosamine-6-phosphate disodium	Endogenous Metabolite	Metabolic Disease
N-Acetyl-D-galactosamine-6-phosphate disodium is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate disodium can be hydrolyze by NagA .

HY-N19420

Theasinensin C	Renin Bacterial Interleukin Related TNF Receptor	Cardiovascular Disease Inflammation/Immunology
Theasinensin C is an orally effective renin inhibitor and gut microbiota modulator, with an IC₅₀ of 40.21 μM against renin activity. Theasinensin C selectively enriches Akkermansia muciniphila in the gut microbiota, enhances the Akkermansia muciniphila-mediated hydrolysis of the PTS domain of mucin, drives the accumulation of luminal glutamine and serine, and regulates the gut-kidney-liver glutamine/serine metabolic signaling pathway to promote creatine biosynthesis. Theasinensin C improves cognitive function, reduces pro-inflammatory cytokines, alleviates neuropathological changes and restores intestinal barrier integrity. Theasinensin C can be used in research related to hypertension and neuroinflammation induced by high-fructose diet .

Cat. No.	Product Name	Target	Research Area

HY-P10230

Sublancin	Bacterial	Infection
Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N19420

Theasinensin C	Structural Classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Renin Bacterial Interleukin Related TNF Receptor
Theasinensin C is an orally effective renin inhibitor and gut microbiota modulator, with an IC₅₀ of 40.21 μM against renin activity. Theasinensin C selectively enriches Akkermansia muciniphila in the gut microbiota, enhances the Akkermansia muciniphila-mediated hydrolysis of the PTS domain of mucin, drives the accumulation of luminal glutamine and serine, and regulates the gut-kidney-liver glutamine/serine metabolic signaling pathway to promote creatine biosynthesis. Theasinensin C improves cognitive function, reduces pro-inflammatory cytokines, alleviates neuropathological changes and restores intestinal barrier integrity. Theasinensin C can be used in research related to hypertension and neuroinflammation induced by high-fructose diet .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73684

	PTS Protein, Human (His) 6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; PTPS; PTS	Human	E. coli
	PTS proteins are critical in the biosynthesis of tetrahydrobiopterin, an important cofactor for aromatic amino acid hydroxylase. It catalyzes the conversion of 7,8-dihydroneopterin triphosphate to 6-pyruvoyltetrahydropterin, a key step in the biosynthetic pathway. PTS Protein, Human (His) is the recombinant human-derived PTS protein, expressed by E. coli , with N-His labeled tag.

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Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Mouse (2) Rat (2) Monkey (2) Dog (2)
Application:	IHC-P (2) ICC/IF (2) IP (2) WB (4) FC (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Phosphorylated (1) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88602

	PEX5 Antibody (YA8286) PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5	WB, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	PEX5 Antibody (YA8286) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEX5.

HY-P82891

	*Phospho-PTS* (Ser19) Antibody (YA2636)** PTPS	WB, IHC-P, IP	Human
	Phospho-PTS (Ser19) Antibody (YA2636) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTS (Ser19).

HY-P88602A

	PEX5 Antibody (YA8286)(PBS only) PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5	WB, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	PEX5 Antibody (YA8286) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEX5.

HY-P82891A

	*Phospho-PTS* (Ser19) Antibody (YA2636)(PBS only)** PTPS	WB, IHC-P, IP	Human
	Phospho-PTS (Ser19) Antibody (YA2636) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTS (Ser19).

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Conjugation
Clonality
Immunogen
Appearance
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Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS11455

PTS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTS Human Pre-designed siRNA Set A contains three designed siRNAs for PTS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS26752

Pts Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Pts Rat Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS20244

Pts Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Pts Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pts gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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