90 Results for "

Pancreatic Lipase

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "Pancreatic Lipase" in MCE Product Catalog:

37
37 Publications Verification
Cat. No.: HY-B0218
CAS No.: 96829-58-2
Synonyms: Tetrahydrolipstatin; Ro-18-0647
Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity . Anti-atherosclerotic effect .
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2
2 Cited Publications
Cat. No.: HY-N7072
CAS No.: 84929-27-1
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells .
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2
2 Cited Publications
Cat. No.: HY-N8599
CAS No.: 531-58-8
Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against α-amylase, α-glucosidase, pancreatic lipase and DPP-IV, with IC50 values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y14R (IC50 = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .
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1
1 Cited Publications
Cat. No.: HY-14471
CAS No.: 282526-98-1
Purity:  ≥98.0%
Synonyms: ATL-962
Target:  

Lipase

Research Areas:  

Metabolic Disease

Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively .
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1
1 Cited Publications
Cat. No.: HY-Y1422B
CAS No.: 9001-62-1
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner. Lipase (MS grade) is involved in a variety of biological processes, from fat metabolism to cell signaling and inflammation, and can be used to study diseases such as pancreatic insufficiency, celiac disease and cystic fibrosis .
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1
1 Cited Publications
Cat. No.: HY-N4167
CAS No.: 6665-74-3
Synonyms: Galangin 3-methyl ether; 3-Methylgalangin
3-O-Methylgalangin (Galangin 3-methyl ether) is a natural flavonoid compound from the rhizome of Alpinia officinarum (AO) with antibacterial activities, which also inhibits pancreatic lipase .
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1
1 Cited Publications
Cat. No.: HY-P75978
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PNLIP; Triacylglycerol Lipase; Pancreatic Lipase; PTL; PL; Triacylglycerol Acylhydrolase; Pancreatic Triacylglycerol Lipase; PNLIPD
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-B0998
CAS No.: 145-41-5
Synonyms: Dehydrocholate sodium
Dehydrocholic acid (Dehydrocholate) sodium is an orally active hydrocholeretic agent. Dehydrocholic acid sodium modulates Autophagy, reduces serum amylase and lipase levels. Dehydrocholic acid sodium has the effects of promoting choleretic function, protecting the liver, reducing pancreatic damage, and regulating cholesterol metabolism. Dehydrocholic acid sodium can be used in the study of acute biliary pancreatitis and obstructive jaundice .
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Cat. No.: HY-W013168
CAS No.: 1492-30-4
Synonyms: 4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp
Target:  

Lipase

Research Areas:  

Others

4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate) is a chromogenic substrate for lipases and esterases. Upon enzymatic hydrolysis, 4-Nitrophenyl palmitate releases p-nitrophenol, which can be quantified by colorimetric detection at 410 nm as a measure of enzymatic activity. 4-Nitrophenyl palmitate is used to characterize the activity of various bacterial and mammalian enzymes, including those from Burkholderia and porcine pancreatic lipase .
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Cat. No.: HY-126411
CAS No.: 28148-89-2
Purity:  96.75%
Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties and blood-brain barrier permeability. Peonidin-3-O-galactoside chloride inhibits pancreatic lipase, with an IC50 value of 23.2 μg/mL against porcine pancreatic lipase. Peonidin-3-O-galactoside chloride mediates neuroprotection, regulates glucose metabolism, protects cells from high glucose-induced damage, promotes glucose uptake and increases ATP production. Peonidin-3-O-galactoside (chloride) can be used in the research of obesity and neurodegenerative diseases .
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Cat. No.: HY-117095
CAS No.: 18323-58-5
Purity:  99.68%
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm) .
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Cat. No.: HY-B1393
CAS No.: 81-23-2
Synonyms: Dehydrocholate
Target:  

Autophagy Amylases Lipase

Research Areas:  

Metabolic Disease

Dehydrocholic acid (Dehydrocholate) is an orally active hydrocholeretic agent. Dehydrocholic acid modulates Autophagy, reduces serum amylase and lipase levels. Dehydrocholic acid has the effects of promoting choleretic function, protecting the liver, reducing pancreatic damage, and regulating cholesterol metabolism. Dehydrocholic acid can be used in the study of acute biliary pancreatitis and obstructive jaundice .
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Cat. No.: HY-110390
CAS No.: 263890-70-6
Purity:  99.61%
GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis .
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Cat. No.: HY-77817
CAS No.: 1003-29-8
Synonyms: 2-Formylpyrrole
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) is a heterocyclic organic compound that serves as a scaffold for the synthesis of various bioactive compounds .
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Cat. No.: HY-W099648
CAS No.: 20671-66-3
Target:  

Lipase

Research Areas:  

Others

4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase .
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Cat. No.: HY-B0218R
CAS No.: 96829-58-2
Synonyms: Tetrahydrolipstatin (Standard); Ro-18-0647 (Standard)
Orlistat (Standard) is the analytical standard of Orlistat. This product is intended for research and analytical applications. Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity . Anti-atherosclerotic effect .
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Cat. No.: HY-W127730
CAS No.: 992-42-7
Pyridoxine 3,4-dipalmitate is a Pyridoxine (HY-B1328) derivative. Pyridoxine exerts its antioxidant effects .
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Cat. No.: HY-W013807
CAS No.: 109-43-3
Synonyms: Dibutyl decanedioate
Research Areas:  

Others

Dibutyl sebacate (Dibutyl decanedioate) is a PVC eco-friendly plasticizer. Dibutyl sebacate plasticizes Eudragit RS 30D, reducing the glass transition temperature and minimum film-forming temperature for sustained-release coatings, with no aging effect .
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Cat. No.: HY-135297
Purity:  97.50%
Research Areas:  

Others

Mono-and diglycerides is formed by triglycerides being broken down by pancreatic lipase in the gastrointestinal lumen. Mono-and diglycerides is a food additive used as a nonionic emulsifier and mainly present in food fats .
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Cat. No.: HY-119741
CAS No.: 200399-47-9
Salacinol, compound found in Salacia reticulata, is an orally active α-glucosidase/lipase inhibitor. Salacinol inhibits enzymatic activity of intestinal maltase (IC50 = 3.2 μg/mL, Ki = 0.31 μg/mL), sucrase (IC50 = 0.84 μg/mL, Ki = 0.32 μg/mL), and isomaltase (IC50 = 0.59 μg/mL, Ki = 0.47 μg/mL), and inhibits increases in serum glucose levels in sucrose-loaded rats. Salacinol also inhibits pancreatic lipase and lipoprotein lipase. Salacinol can be used for the research of diabetes mellitus .
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