28148-89-2
Chemical Structure
Peonidin-3-O-galactoside chloride
- CAS No.: 28148-89-2
- Formula:C22H23ClO11
- Molecular Weight:498.86
IUPAC Name: 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chromenylium chloride
InChIKey: VDTNZDSOEFSAIZ-HVOKISQTSA-N
SMILES: COC1=CC(C2=C(O[C@H]3[C@@H]([C@H]([C@H]([C@@H](CO)O3)O)O)O)C=C4C(C=C(O)C=C4O)=[O+]2)=CC=C1O.[Cl-]
Biological Activity: Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties and blood-brain barrier permeability. Peonidin-3-O-galactoside chloride inhibits pancreatic lipase, with an IC50 value of 23.2 μg/mL against porcine pancreatic lipase. Peonidin-3-O-galactoside chloride mediates neuroprotection, regulates glucose metabolism, protects cells from high glucose-induced damage, promotes glucose uptake and increases ATP production. Peonidin-3-O-galactoside (chloride) can be used in the research of obesity and neurodegenerative diseases[1][2][3][4].
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Peonidin-3-O-galactoside chloride | 97.07% | Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties and blood-brain barrier permeability. Peonidin-3-O-galactoside chloride inhibits pancreatic lipase, with an IC50 value of 23.2 μg/mL against porcine pancreatic lipase. Peonidin-3-O-galactoside chloride mediates neuroprotection, regulates glucose metabolism, protects cells from high glucose-induced damage, promotes glucose uptake and increases ATP production. Peonidin-3-O-galactoside (chloride) can be used in the research of obesity and neurodegenerative diseases. | ||||||||||||||||||||
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- [1]. Xie L, et al. Discovery of anthocyanins from cranberry extract as pancreatic lipase inhibitors using a combined approach of ultrafiltration, molecular simulation and spectroscopy. Food & Function, 2020, 11(10): 8606-8618.
- [2]. Tulio AZ, et al. Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits[J]. Food Chemistry, 2014, 164: 158-166.
- [3]. Liaudanskas M, et al. Determination of Biologically Active Compounds and Antioxidant Capacity In Vitro in Fruit of Small Cranberries (Vaccinium oxycoccos L.) Growing in Natural Habitats in Lithuania. Antioxidants (Basel). 2024 Aug 28;13(9):1045.
- [4]. Liu X, et al. Pharmacokinetics, Tissue Distribution, and Metabolic Profile of Cyanidin 3-O-β-Galactoside Purified From Black Chokeberry. Mol Nutr Food Res. 2025;69(21):e70219. [Content Brief]
Keywords
