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Results for "

PyM

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

1

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W009641
    1-Pyrenemethanol

    PyM; 1-HMP

    		 Biochemical Assay Reagents Others
    1-Pyrenemethanol is an organic compound that can be used to prepare graphene films with excellent thermal conductivity, flexibility and mechanical properties. 1-Pyrenemethanol binds to graphene oxide sheets through hydrogen bonds and π-π interactions to form GO-PyM films, increasing the dispersion and stability of the material .
    1-Pyrenemethanol
  • HY-RS11494
    PYM1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PYM1 Human Pre-designed siRNA Set A contains three designed siRNAs for PYM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PYM1 Human Pre-designed siRNA Set A
    PYM1 Human Pre-designed siRNA Set A
  • HY-P11581
    MNP2

    		NOD-like Receptor (NLR) Interleukin Related Caspase Amyloid-β Tau Protein α-synuclein Pyroptosis Neurological Disease
    MNP2 is a NLRP3-ASC interaction inhibitor. MNP2 selectively binds to the PYD domain of ASC (Ka=149 nM) and blocks ASC-PYM binding (Ka=58 nM), thereby inhibiting the interaction between ASC and NLRP3 and suppressing the formation of the NLRP3 inflammasome. MNP2 inhibits IL-1β release and caspase-1 maturation, and reduces the efflux of potassium and chloride ions. MNP2 prevents mitochondrial damage and reactive oxygen species production, and significantly decreases NLRP3 inflammasome formation in neurodegenerative pathologies induced by β-amyloid, Tau protein and α-synuclein. MNP2 is applicable for the research of neurodegenerative diseases .
    MNP2

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