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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
SCC
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "SCC" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation.
2
2 Cited Publications
Synonyms: Gumarontinib; SCC244
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Research Areas:
Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, TyrO3. Antitumor activity .
2
2 Cited Publications
Cat. No.: HY-P81223
Synonyms: Cholesterol 20 22 desmolase antibody
Cholesterol desmolase antibody;
Cholesterol monooxygenase (side chain cleaving) antibody;
Cholesterol side chain cleavage enzyme antibody;
Cholesterol side chain cleavage enzyme mitochondrial antibody;
Cholesterol side-chain cleavage enzyme antibody;
CP11A_HUMAN antibody;
CYP11A antibody;
CYP11A1 antibody;
CYPXIA1 antibody;
Cytochrome P450 11A1 antibody;
Cytochrome P450 11A1 mitochondrial antibody;
Cytochrome P450 family 11 subfamily A polypeptide 1 antibody;
Cytochrome P450 subfamily XIA antibody;
Cytochrome P450(SCC) antibody;
Cytochrome P450C11A1 antibody;
mitochondrial antibody;
P450SCC antibody;
Steroid 20 22 lyase antibody;
Cat. No.: HY-172526
CAS No.: 3082361-42-7
4A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection .
Cat. No.: HY-10984A
CAS No.: 202271-89-4
Synonyms: (S)-CC-4047
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Research Areas:
(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies .
Cat. No.: HY-W127393
CAS No.: 177158-21-3
Cat. No.: HY-101595
CAS No.: 96558-24-6
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RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance .
Cat. No.: HY-P10780
Synonyms: Neuropeptide NPVF (mouse)
Research Areas:
Cat. No.: HY-125049
CAS No.: 78798-08-0
Synonyms: Sch 25663
Target:
Cat. No.: HY-170843
Antitumor agent-198 (Compound A3) exhibits cytotoxicity in head and neck squamous cell carcinoma (HNSCC) cells, that inhibits the proliferation of CAL27, HN6, HN30, SCC9 and SCC25 with IC50 of 4 nM-77 nM. Antitumor agent-198 inhibits the HNSCC cell migration, arrests the cell cycle, and induces apoptosis .
Cat. No.: HY-RS12711
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SERPINB3 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINB3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990159
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Cat. No.: HY-15495B
CAS No.: 2517855-91-1
Synonyms: (3S)-CC-930 hydrochloride
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(3S)-Tanzisertib (hydrochloride) ((3S)-CC-930 (hydrochloride)) is an orally active JNK inhibitor (IC50 values for JNK1, JNK2, and JNK3 are 61, 7, and 6 nM, respectively). (3S)-Tanzisertib (hydrochloride) selectively inhibits ERK1, p38α, and EGFR (IC50 = 0.48, 3.4, and 0.38 μM, respectively). (3S)-Tanzisertib (hydrochloride) inhibits LPS-induced TNFα production in an acute rat PK-PD model. (3S)-Tanzisertib (hydrochloride) can be used in idiopathic pulmonary fibrosis (IPF) research .
Cat. No.: HY-178029
Research Areas:
RSK2/TOP2-IN-1 is a RSK2/TOP2 dual inhibitor. RSK2/TOP2-IN-1 targets key tumor progression enzymes including ribosomal S6 kinase 2 and topoisomerases IIα/IIβ. RSK2/TOP2-IN-1 shows selectivity index > 2 against all squamous cell carcinoma (SCC) cell lines. RSK2/TOP2-IN-1 can induce cell apoptosis, autophagy and ROS production. RSK2/TOP2-IN-1 can be used for the research of cancer, such as squamous cell carcinoma .
Cat. No.: HY-RS17479
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Research Areas:
Cyp11a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cyp11a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81402A
Synonyms: SA 2; SA-2; SA2; SCC3 homolog 2; SCC3B; stag2; Stromal antigen 2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
