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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
SMCC
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "SMCC" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: DM1-SMCC
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SMCC-DM1 (DM1-SMCC) is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody agent conjugate (ADC) .
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7 Cited Publications
Cat. No.: HY-P9921A
CAS No.: 1018448-65-1
Synonyms: Ado-Trastuzumab emtansine (solution); PRO132365 (solution); T-DM 1 (solution)
5
5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
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1 Cited Publications
Cat. No.: HY-42360
CAS No.: 64987-85-5
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SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
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1 Cited Publications
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Doxorubicin-SMCC is a agent-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin .
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1 Cited Publications
Synonyms: Lys-Nε-MCC-DM1
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Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer .
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MMAE-SMCC is a agent-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody agent conjugate.
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DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker .
Cat. No.: HY-150043A
Purity: 95.64%
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MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.
Cat. No.: HY-P99685
CAS No.: 1622327-37-0
Synonyms: IMGN-289; J2898A-SMCC-DM1
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Cat. No.: HY-159774
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ADC Control human IgG1-DM1 is the ADC control, which is composed of Human IgG1 kappa, Isotype Control (HY-P99001) and the linker-payload conjugate SMCC-DM1 (HY-101070) .
Cat. No.: HY-164763
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SHR-A1201 is a HER2-targeting antibody-drug conjugate (ADC). SHR-A1201 is composed of a humanized anti-HER2 antibody (HY-P9907), a linker SMCC (HY-42360), and a microtubulin inhibitor payload Mertansine (HY-19792). SHR-A1201 can be used for research in HER2-positive breast cancer .
Cat. No.: HY-101982A
Purity: 98.18%
Synonyms: (Rac)-Lys-Nε-MCC-DM1
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(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1 .
Cat. No.: HY-150043
CAS No.: 2102021-49-6
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MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-D2396
Synonyms: Sulfo SMCC R-PE
Cat. No.: HY-W123007
CAS No.: 125559-00-4
Synonyms: Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate)
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LC-SMCC (Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate)) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-135125
CAS No.: 615538-48-2
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DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC). DC4 can be used for the targeted treatment of cancer .
Cat. No.: HY-155791
CAS No.: 2451934-98-6
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SMCC-NH-CH2-triazole-PEG8-oxydiacetamide-Lys(MTT)-PAB (Page 7, Compound C) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
