1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MMAE-SMCC

MMAE-SMCC 

Cat. No.: HY-135660
Handling Instructions

MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate.

For research use only. We do not sell to patients.

MMAE-SMCC Chemical Structure

MMAE-SMCC Chemical Structure

CAS No. : 2021179-11-1

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Description

MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].

IC50 & Target[1]

Auristatin

 

Molecular Weight

1140.43

Formula

C₅₈H₈₉N₇O₁₄S

CAS No.

2021179-11-1

SMILES

O[[email protected]@H](C1=CC=CC=C1)[[email protected]@H](C)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]@]([[email protected]@H](C)CC)([H])N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)C(CCSC(C3)C(N(CC4CCC(C(ON5C(CCC5=O)=O)=O)CC4)C3=O)=O)=O)=O)=O)=O)OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MMAE-SMCCDrug-Linker Conjugates for ADCcancertoxinlinkerInhibitorinhibitorinhibit

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